Speaker
Dr
John Prior
(Nuclear Medicine Department, CHUV University Hospital)
Description
This presentation will give an overview of molecular imaging tools (nuclear, optical imaging) and their possible use in the operating room in guiding oncologic abdominal surgery. For instance, the role of surgery in metastatic/recurrent cancer is currently being redefined, as new diagnostic tools and treatments are available: metastasectomy and cytoreductive can be considered viable management in selected cases. Probes sensitive to β+ radiation (positrons) used in combination with specific radiopharmaceuticals offer superior sensitivity for real-time localization of tumoral lesions and the ability to link tumor biological characteristics to preoperative positron emission tomography. Moreover, these probes are exquisitely sensitive and have been reported to detect micro-metastases in lymph nodes missed by conventional histopathological examination or preoperative imaging and only detected when ultrathin histopathological analysis of resected lymph nodes was requested.
Author
Dr
John Prior
(Nuclear Medicine Department, CHUV University Hospital)
Co-authors
Dr
Nicolas Demartines
(Visceral Surgery Department, CHUV University Hospital)
Dr
Vincent Dunet
(Nuclear Medicine Department, CHUV University Hospital)