10–16 Jun 2018
Dalhousie University
America/Halifax timezone
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*** Withdrawn *** Soma-dendrite interaction enhances noisy signal encoding

11 Jun 2018, 17:30
15m
SUB 302 (cap.40) (Dalhousie University)

SUB 302 (cap.40)

Dalhousie University

Oral (Non-Student) / Orale (non-étudiant(e)) Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB) M3-1 Stochastic Biology (DPMB) I Biologie stochastique (DPMB)

Speaker

Prof. Andre Longtin (University of Ottawa)

Description

Dendrites are often excitable structures involved in the signal processing of almost all neurons.
We find that when an active dendrite has a greater intrinsic variability and a longer refractory period
than the soma, it will determine spike times for weak inputs but be entrained by somatic spikes for
strong inputs. This produces an input-dependent gating of dendritic noise. As a result, populations
of dendrite-soma systems improve transmission of sub- and suprathreshold signals for a large range
of intrinsic dendritic noise. This novel mechanism suggests a functional role for active dendrites.

link.aps.org/pdf/10.1103/PhysRevX.7.031045

Primary authors

Prof. Richard Naud (University of Ottawa) Dr Alexandre Payeur (University of Ottawa) Prof. Andre Longtin (University of Ottawa)

Presentation materials

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