Conveners
T4-7 Physics of Biosensing (DPMB) | Physique de la biodétection (DPMB)
- Francis Lin (University of Manitoba)
Miniaturized biosensors are essential components of continuous health monitoring systems, which are expected to significantly impact human health management. Biosensors integrate biorecognition elements with transducers to detect the presence, absence, and quantity of biologically-relevant elements. Nanoscale materials play a critical role in enhancing the sensitivity and specificity of these...
Antimicrobial Peptides (AMPs) are small chains of between 10 and 50 amino acids with the ability to kill pathogens such as bacteria, fungus, viruses, and even cancer cells. AMPs are one of many mechanisms that living organism have developed to protect themselves from pathogenic microorganisms. Most research in AMPs is focused on understanding the mechanism or mechanisms that AMPs use to kill...
Bacterial pathogens can be differentiated via an elemental analysis technique known as laser-induced breakdown spectroscopy (LIBS). This technique can be of use in the rapid identification of bacterial pathogens, for which there is a high demand, particularly in a clinical setting. The identification of bacteria with LIBS must therefore be possible with the types and numbers of bacterial cells...
G protein coupled receptors (GPCRs) are a superfamily of membrane receptors known for high signal transduction efficiencies. One of the key aspects of the GPCR signaling mechanism is the coupling interaction between the receptor and the G protein in response to external stimuli. We examined the pre-stimulus receptor-G protein coupling state by single-particle tracking (SPT) of M$_2$ muscarinic...
