Description
Chair: Marco Durante (GSI and TU Darmstadt), Rapporteur: Bleddyn Jones (Univ.of Oxford)
Gillies McKenna
(Gray Institute for Radiation Oncology & Biology, Oxford)
02/02/2010, 13:30
Oliver Jaekel
(DKFZ, Heidelberg)
02/02/2010, 14:00
Dr
Gisela Taucher-Scholz
(GSI Biophysics, Darmstadt, Germany)
02/02/2010, 14:30
Radiobiology in therapy and space science
Oral presentations
Double-strand breaks (DBSs) are critical lesions and their spatial distribution is crucial regarding repair capability and biological effects. Ion irradiation leads to streaks of spatially localized damaged chromatin domains across cell nuclei revealed by repair protein immunostaining. Efficient repair after carbon ion irradiation is indicated by loss of the DSB marker H2AX, but repair is...
Dr
Petteri Nieminen
(ESA)
02/02/2010, 14:45
Radiobiology in therapy and space science
Oral presentations
The space radiation environment is a highly variable and dynamic one, with a number of constituent particle sources that need to be individually considered depending on the type of space mission planned. The Galactic Cosmic Rays form a slowly varying higher-energy background over the 11-year solar cycle, on top of which the sporadic, lower-energy, but essentially unpredictable Solar Particle...
Dr
Marco Silari
(CERN)
02/02/2010, 15:00
Radiobiology in therapy and space science
The feasibility is presented of setting-up an experimental facility at CERN, to be made available to European institutes, for research in radiobiology and dosimetry with light-ion beams, with minimum impact on CERN main activities. The possibility is first discussed of injecting and decelerating protons rather than antiprotons in the AD, providing beams with kinetic energies in the range 5–300...
Dr
Giuseppe Battistoni
(INFN MILANO)
02/02/2010, 15:45
Radiobiology in therapy and space science
Biological calculations in tumour therapy with ions depend on a precise description of the radiation field. In carbon ion irradiation, nuclear reactions cause a significant alteration of the radiation field. Therefore, the contribution of secondary fragments needs to be taken into account for accurate planning of the physical and biological dose delivery in the scheduled treatment....
Dr
Michael KRAEMER
(GSI)
02/02/2010, 16:00
Radiobiology in therapy and space science
Oral presentations
A major issue of modern radiotherapy is the delivery of
sufficiently high dose to the target, whereas the exposure
of healthy tissue should be minimized.
Swift light ions offer significant physical and radiobiological advantages
compared to photon radiation.
So far the technologically most advanced project to apply charged particles
in radiotherapy was the GSI pilot project, now followed...
Dr
Andrea Attili
(on behalf of the INFN-TPS collaboration)
02/02/2010, 16:15
Radiobiology in therapy and space science
Oral presentations
Several technologies developed by the Italian institute of nuclear physics (INFN) for fundamental physics have been applied to medical imaging and particle therapy techniques. The partnership with leading industries has always been crucial for successful applications. Within this framework is the implementation of a Treatment Planning System (TPS) for hadrontherapy with C-ion beams, but not...
Dr
Yolanda Prezado
(European synchrotron Radiation Facility)
02/02/2010, 16:30
Radiobiology in therapy and space science
Oral presentations
Synchrotron radiation (SR) therapy is a promising alternative to treat brain tumors, whose management is limited due to the high morbidity of the surrouding healthy tissues. Several approaches are being explored by using SR. The European Synchrotron Radiation Facility (ESRF) in Grenoble (France) has devoted one of its lines to biomedical research, highly focused nowadays to the development of...
