The requirements to bring non-conventional isotopes to clinical uses - Prof. C. Decristoforo

Curriculum Vitae

Curriculum Vitae Clemens Decristoforo, Univ.Doz, Prof h.c., Mag., Dr.

Personal Data

Date of Birth March 19, 1965

Place of Birth Innsbruck Austria

Nationality Austria Married, 3 children

 

Education and career

1991 M Pharm

1991-1997 Radiopharmacist Clinical Department of Nuclear Medicine Innsbruck, Austria

1997 Dr.rer. nat. (equ Ph.D.)

1997-1998 Post Doc Marie Curie Fellow at the Nuclear Medicine Research Laboratory, St Bartholomews Hospital, QMW college, London.

2001 Habilitation (venia docendi) for Radiopharmacy

Since 1998 Radiopharmacist Clinical Department of Nuclear Medicine Innsbruck, Austria

08/09-03/2010 Radiopharmaceutical Scientist, Industrial Applications and Chemistry Section, Division of Physical and Chemical Sciences, IAEA, Vienna, Austria

March 2010 Radiopharmacist Clinical Department of Nuclear Medicine Innsbruck and Dozent at the Medical University Innsbruck, Austria

October 2014 Honorary Professor Medical University Innsbruck

 

Research interests: Radiopharmaceuticals, Radiometal labeled peptides for diagnosis and therapy, Ga-68, radiolabelled siderophores, targeted radionuclide therapy.

 

Awards Erwin Schrödinger fellowship/1997-98, Marie Curie Fellowship 1997-1998, Pfeiffer Scholarship of the Austrian Society of Nuclear Medicine 1999, British Nuclear Medicine Society Annual Meeting 2000, Pfeiffer Stipendium ÖGN 2004, Mallinckrodt Price OGN 2012, THP Preis 2012+2015, Best non clinical paper EJNMMI 2012

 

Memberships: Editorial Board European Journal of Nuclear Medicine and Molecular Imaging (EJNMMI, Springer),

Editorial Board EJNMMI Research, EJNNMI Radiopharmacy& Chemistry, Clinical Transl.Imaging

Radiopharmacy Committee European Association of Nuclear Medicine,

Member of Expert Group 14 European Pharmacopeia (EDQM, Strasbourg)

 

Teaching: Medical University of Innsbruck: Radiopharmacy, Molecular Imaging, Nuclear Medicine, Postgraduate European Radiopharmacy Course Supervisor: PhD: 9

 

Conferences: Organizer of the 11^th European symposium on Radiopharmacy and Radiopharmaceuticals (ESRR) Innsbruck 15.-18.March 2003 and 18^th ESRR 7.-10. April 2016

Local Organizer 13. Arbeitsttreffen der AG Radiochemie/Radiopharmazie Seefeld Sept 2005

Scientific Committee Member EANM Annual Congress 2008, 2009, ESRR 2003-2016

Scientific Committee 18^th International Symposium on Radiopharmaceutical Sciences 2009

 

Selected Recent Invited Oral Presentations

• Annual Meeting of the Eur. Ass. of Nuclear Medicine, Vienna October 25^th 2015 Highlights Lecture
• ASM Microbe, Boston, June 17^th 2016 Targeted Molecular Imaging of Fungal Infections Using PET
• 11^th Annual fungal update, St.Bartholomews Hospital London, Feb.6^th 2016 Beyond the halo sign – towards pathogen identification using CT-PET
• Annual Meeting of the Eur. Ass. of Nuclear Medicine, Hamburg October 14^th 2015 Highlights Lecture
• Annual Meeting of the Australian and New Zealand Society of Nuclear Medicine, Adelaide, Australia April 27^th 2014, Novel agents for infection imaging - Ga-68 labelled siderophores

 

Cooperations: COST B3, COST B12, COST BM0607, IAEA expert missions and research projects, ERA-Net-Transcan, FP7-MITIGATE

 

Grants: FWF (P30924-B26) Modified Siderophores for “Theranostics” of Aspergillosis 2018

FWF (P25899-B23) Novel radiometal chelators to develop targeted labelled biomolecules for PET 2013

ERA-NET Transcan A novel biomarker for medullary thyroid cancer (GRAN-T-MTC), FWF I 1224-B19 2013

FWF (L676) ⁶⁸Ga-siderophores for diagnosis of aspergillosis with PET 2009

Radiolabelled Nanoparticles for specific molecular targeting in oncology, ProjectNr. 815844: V0208-Z07-BI, Austrian NANO Initiative 2008

 

Reviewer: EJNMMI, JNM, Nucl Med Biol, Biocon Chem, Mol Pharm, Eur J Pharm Sci, EJNMMI research, JLCR, JMC, Nuc Med Commun, Bone, Sci Pharm, Mol Imag, MIB,

DFG, Swiss cancer league, FWO, Dutch cancer Soc

 

Publications:

115 original papers, 11 reviews, 10 letters, 12 book chapters, >200 published abstracts

Selected Publications on radiopharmaceutical regulations:

1. Clemens Decristoforo, Ivan Penuelas, Marianne Patt, Sergio Todde: European rules to bring novel radiopharmaceuticals to the clinic. Quarterly Journal of Nuclear Medicine and Molecular Imaging 01/2017; 61(2)., DOI:10.23736/S1824-4785.17.02965-X
2. Clemens Decristoforo, Marianne Patt: Are we “preparing” radiopharmaceuticals?. 01/2017; 1(1)., DOI:10.1186/s41181-016-0011-7
3. J. Koziorowski, M. Behe, C. Decristoforo, J. Ballinger, P. Elsinga, V. Ferrari, P. Kolenc Peitl, S. Todde, T. L. Mindt: Position paper on requirements for toxicological studies in the specific case of radiopharmaceuticals. 01/2017; 1(1)., DOI:10.1186/s41181-016-0004-6
4. Dariusz Pawlak, Christine Rangger, Petra Kolenc-Peitl, Piotr Garnuszek, Michał Maurin, Laura Ihli, Marko Kroselj, Theodosia Maina, Helmut Maecke, Paola Erba, Leopold Kremser, Alicja Hubalewska-Dydejczyk, Renata Mikołajczak, Clemens Decristoforo: From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial. European Journal of Pharmaceutical Sciences 01/2016; 85., DOI:10.1016/j.ejps.2016.01.023
5. Rogier Lange, Rob ter Heine, Clemens Decristoforo, Iván Peñuelas, Philip H. Elsinga, Monique M L van der Westerlaken, N. Harry Hendrikse: Untangling the web of European regulations for the preparation of unlicensed radiopharmaceuticals. Nuclear Medicine Communications 02/2015; 36(5):1., DOI:10.1097/MNM.0000000000000276
6. Joel Aerts, James R. Ballinger, Martin Behe, Clemens Decristoforo, Philip H. Elsinga, Alain Faivre‐Chauvet, Thomas L. Mindt, Petra Kolenc Peitl, Sergio C. Todde, Jacek Koziorowski: Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: A European perspective. Journal of Labelled Compounds 08/2014; 57(10)., DOI:10.1002/jlcr.3227
7. C Decristoforo, I Penuelas, P Elsinga, J Ballinger, A D Winhorst, A Verbruggen, F Verzijlbergen, A Chiti: Radiopharmaceuticals are special, but is this recognized? The possible impact of the new Clinical Trials Regulation on the preparation of radiopharmaceuticals. European journal of nuclear medicine and molecular imaging 07/2014; 41(11)., DOI:10.1007/s00259-014-2838-z
8. Clemens Decristoforo, Roger D Pickett, Alfons Verbruggen: Feasibility and availability of 68Ga-labelled peptides. European Journal of Nuclear Medicine 03/2012; 39 Suppl 1(S1):S31-40., DOI:10.1007/s00259-011-1988-5
9. Clemens Decristoforo, Sally W. Schwarz: Radiopharmacy: Regulations and legislations in relation to human applications. Drug Discovery Today Technologies 06/2011; 8(s 2–4):e71–e77., DOI:10.1016/j.ddtec.2011.11.012
10. A Decristoforo, I Peñuelas: Towards a harmonized radiopharmaceutical regulatory framework in Europe?. The quarterly journal of nuclear medicine and molecular imaging: official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.. 08/2009; 53(4):394-401.