Speaker
Description
Hadron therapy is an innovative type of radiotherapy for cancer treatment which enables tumour cells to be more effectively destroyed than conventional radiotherapy using photons. The precise knowledge of the lineal energy of particles is used in the field of microdosimetryas a fundamental parameter in the prediction of the relative biological efficiency (RBE) of clinical beams.The access to these experimentally measured quantity is essential for validating simulations and models that are currently used to improve the treatment efficiency. Currently, no such a microdosimetric detector is available on the market for routine clinical use.
Within the frames of this PhD project novel prototypes of solid-state microdosimeters based on single-crystal CVD diamond membranes, for such lineal energy measurements have be developed. Their response to single projectiles was investigated in ion microbeams (IBIC) and compared with theoretical predicted results using Monte Carlo and TCAD simulations, showing very promising results. At this stage, the microdosimeter prototypes of the device are integrated with suitable multi-channel electronics. Finally, their full performance will be evaluated with clinical proton and carbon beams leading to first step for the implementation in radiobiological models.
