Conveners
M3-3 Molecular and Soft Matter Biophysics (DPMB/DCMMP) | Biophysique moléculaire et de la matière molle (DPMB/DPMCM)
- Cornelia Hoehr
In recent years, the drug discovery industry has seen a steady decline in productivity due partially to the difficulty in rationally designing and exploring novel search spaces. At the same time, cutting-edge deep learning techniques offer the possibility of rapidly enhancing design of novel biomolecules, but suffer from a lack of interpretability. By employing physics-based techniques,...
Carbon nanotube field-effect biosensors (CNT-bioFETs) are ultraminiaturized devices that can be used to measure single-molecule kinetics of biomolecules. They monitor time scales going from a few microseconds to several minutes, as demonstrated for nucleic acid folding and enzyme function. The sensitivity of CNT-bioFETs originates from the interplay between the nanotube’s conductance, which is...
In response to the retirement of the NRU Reactor at Chalk River Laboratories, a group of Canadian neutron scatterers, cancer clinicians and researchers, and accelerator physicists are carrying out an initial design of a prototype Canadian compact accelerator-based neutron source (PC-CANS) in Canada. The PC-CANS will help mitigate the challenges to maintain and expand the scientific resources...
Wet adhesion is critical for many engineering, biomedical and dental applications; yet, current man-made glues and cements are ineffective on wet surfaces. Mussels, however, can glue themselves firmly on seashore surfaces using protein-based fibers known as byssal threads, each of which terminates in a small adhesive plaque. The byssal plaque is an important role model for understanding...
