# Fast Timing in Medical Imaging

Jun 3 – 5, 2022
Parador El Saler, Valencia, Spain
Europe/Zurich timezone

## Exploration of the physical limits for Cherenkov PET using tiny crystals and a large cube

Jun 3, 2022, 5:00 PM
15m
Parador El Saler, Valencia, Spain

#### Parador El Saler, Valencia, Spain

System considerations for pushing TOFPET CTR ≤ 100ps

### Speaker

Sofiia Forostenko (ETH Zurich (CH))

### Description

This study is performed within the scope of the SwissPix project, which aims at developing a new photo-sensor for Positron Emission Tomography with ~10 ps FHWM timing resolution, capable of exploiting the prompt nature of Cherenkov radiation. Using Monte Carlo simulations, we estimated the physical limits of timing resolution for two possible detector geometries: a radiator of 3x3x3 mm$^3$ with one photo-sensor attached opposite to the side the gamma enters, and a 25x25x25 mm$^3$ cube with photo-sensors fully covering all six sides. The 25x25x25 mm$^3$ cube required reconstruction of the gamma interaction position that it performed using arrival times and the Cherenkov photons detection positions, minimizing a cost function for the gamma interaction position. Monte Carlo information confirmed the reconstruction of the gamma interaction position inside the cube. We simulated a whole-body PET system with GATE (Geant4 Application for Tomographic Emission). As a result, the spatial resolution in three directions of the point source was obtained reconstruction-less.

### Primary authors

Sofiia Forostenko (ETH Zurich (CH)) Werner Lustermann (ETH Zurich (CH))