Conveners
Applications: 1
- Ralf Hendrik Menk (Elettra Sincrotrone Trieste)
Applications: 2
- Matthieu Boone
Applications: 3
- renata longo (University of Trieste & INFN)
Applications: 4
- Valeria Rosso (University of Pisa, Pisa, Italy)
I will discuss fast optical cameras based on the back-illuminated silicon sensor and Timepix3 data driven readout. The intensified version of the camera is single photon sensitive and since recently has been used for a variety of quantum imaging and other applications. I will talk about recent results and new ideas, focusing on topics of quantum-assisted astronomical interferometers. I will...
The development of direct pixelated detectors has played a key role in the resolution revolution in which structures of macromolecular complexes are obtained at near-atomic resolution by cryo-EM [1]. Monolithic active pixel sensor (MAPS) detectors are currently widely applied for cryo-EM, however, they have their best performance at 300 keV and have relatively low readout speed. The Timepix3,...
The possibility to implement the beneficial outcomes of FLASH effect in clinical practice lately has been object of extensive research activity. From the experimental point of view a significant challenge is related to the monitoring at FLASH intensities of therapeutic beams, since conventional monitors are affected by saturation effects and discharges due to the extremely high instantaneous...
Cancer treatments have been performed with X-rays and ions (e.g., protons and carbon ions) over the years. The high dose conformity that allows better sparing of healthy tissue is a demonstrated advantage of carbon ions over x-rays [1]. This dose conformity can be impacted by to anatomical changes between treatment fractions, which can lead to an increase of the dose to healthy tissue and to a...
Spectral and phase-contrast imaging techniques have been widely exploited at synchrotron radiation facilities. Their implementation requires in many cases the use of crystals either to prepare or to analyze the X-ray beam. For instance, energy dispersive spectral systems make use of multiple or bent crystal monochromators to spatially resolve different energy components at the detector...
New generation of synchrotron and plasma accelerators will produce coherent radiation with extremely high brightness. Photon beams from these machines will greatly extend the present research capabilities and will reveal new opportunities in imaging, spectroscopy, structural and dynamic studies, and other applications. Development of beam diagnostic instrumentation with high precision becomes...
Established methods for high-resolution X-ray structure determination are based on far-field coherent diffractive imaging (CDI). However, in the interaction of light with matter incoherent processes occur, that are sometimes predominant over the coherent ones. They are considered detrimental in the CDI approach. The approach called incoherent diffractive imaging (IDI) opens up fundamentally...
Photon counting detectors can enable increased spatial resolution and improved contrast and/or lower radiation dose. In particular, lower concentrations of iodine can potentially be detected and quantified, which is important in angiography or perfusion imaging. Moreover, beam hardening artefacts will disappear with material base decomposition in the projection domain. Electronic noise can be...
A novel irradiation platform for pre-clinical proton therapy studies foresees proton imaging for positioning and accurate treatment planning [1]. While proton imaging at synchrocyclotron-based proton therapy centers is challenging in single particle tracking mode due to high instantaneous particle fluxes, it is feasible in integration mode. Large-area CMOS sensors allow the determination of a...
Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. The INSIDE system, installed at the National Center of Oncological Hadron therapy (CNAO), has acquired in-beam PET data during several patient proton therapy treatments. Despite the fact that PET treatment monitoring...
Proton and ion beams are commonly used worldwide for radiation therapy, offering advantageous dose distribution and increased relative biological effectiveness (RBE) compared to photons. While the RBE is assumed to vary with linear energy transfer (LET) of particles, currently only the constant RBE is taken into account in treatment planning due to a lack of tools for its experimental...
To study the 'proton Computed Tomography' (pCT) technique the INFN-Prima collaboration has built and successfully tested a 20x5cm2 field of view system based on a silicon microstrip tracker and a YAG:Ce scintillating calorimeter. This apparatus has demonstrated the feasibility of the pCT for objects with size suitable for pre-clinical studies [1]. Recently a possible clinical application of...
At 40 years from its invention, this presentation would like to remember the history of the Semiconductor Drift Detector (SDD) since its conception by E. Gatti and P. Rehak, the technological efforts and studies done in Brookhaven, Milan and Munich to develop the first prototypes, the many different device topologies conceived, the theoretical studies and the many applications in which SDDs...
The Large Hadron Collider (LHC) at CERN will be upgraded to the High-Luminosity LHC (HL-LHC) until 2029. In order to fully exploit the physics potential of the high luminosity era the experiments must undergo major upgrades. In the context of the upgrade of the Compact Muon Solenoid (CMS) Experiment the silicon tracker will be fully replaced. The outer part of the new tracker (Outer Tracker)...
ITk detector, the new ATLAS tracking system at High Luminosity LHC, will be equipped with 3D pixel sensor modules in the innermost layer (L0). The pixel cell dimensions will be either 25x100 ยตm2 (barrel) or 50x50 ยตm2 (endcap), with one read-out electrode at the centre of a pixel and four bias electrodes at the corners. Sensors from pre-production wafers (50x50 ยตm2) produced by FBK have been...
We present the experimental characterization of a fast spectroscopic imager for real-time room-temperature detection of low-density contaminants in food production lines. The presented imager is part of XSpectraยฎ, an innovative inspection technology which combines a fast X-ray detection hardware and neural network processing techniques to improve the current limits in detection systems for...
In this work the properties of 200 ฮผm thick highly pixelated LGAD sensors bonded to a Timepix3 readout ASIC were characterised for the first time. Recent advances in the control of the LGAD fabrication process by Micron Semiconductor Ltd has allowed the manufacture of highly segmented devices where each pixel has an internal gain. Devices with 55 ฮผm pixel with 5 ฮผm Junction Termination Element...
