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Dr Christophe Blanchet (CNRS IBCP), Mr Vincent Lefort (CNRS IBCP)01/03/2006, 14:00Life ScienceOral contributionOne of current major challenges in the bioinformatics field is to derive valuable information from the complete genome sequencing projects, which provide the bioinformatics community with a large number of unknown sequences. The first prerequisite step in this process is to access up-to-date sequence and 3D-structure databanks (EMBL, GenBank, SWISS-PROT, Protein Data Bank...) maintained...Go to contribution page
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Dr Christophe Blanchet (CNRS IBCP), Mr Rรฉmi Mollon (CNRS IBCP)01/03/2006, 14:15Life ScienceOral contributionIntroduction Biomedical applications are pilot ones in the EGEE project [1][2] and have their own virtual organization: the โbiomedโ VO. Indeed, they have common security requirements such as electronic certificate system, authentication, secured transfer; but they have also specific ones such as fine grain access to data, encrypted storage of data and anonymity. Certificate system...Go to contribution page
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Dr Luciano Milanesi (National Research Council - Institute of Biomedical Technologies)01/03/2006, 14:30Life ScienceOral contributionProject descriptions The European Commission promotes the Bioinformatics Grid Application for life science (BIOINFOGRID) project. The BIOINFOGRID project web site will be available at http://www.itb.cnr.it/bioinfogrid. The project aims to connect many European computer centres in order to carry out Bioinformatics research and to develop new applications in the sector using a...Go to contribution page
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Silvano Paoli (ITC-irst)01/03/2006, 14:45Life ScienceOral contributionAbstract BioDCV is a distributed computing system for the complete validation of gene profiles. The system is composed of a suite of software modules that allows the definition, management and analysis of a complete experiment on DNA microarray data. The BioDCV system is grid-enabled on LCG/EGEE middleware in order to build predictive classification models and to extract the most...Go to contribution page
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Ms Nadezhda Fialko (research fellow)01/03/2006, 15:00Life ScienceOral contributionRecently, at the interface of physics, chemistry and biology, a new and rapidly developing research trend has emerged concerned with charge transfer in biomacromolecules. Of special interest to researchers is the electron and hole transfer along a chain of base pairs, since the migration of radicals over a DNA molecule plays a crucial role in the processes of mutagenesis and...Go to contribution page
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Mr Jean Salzemann (IN2P3/CNRS)01/03/2006, 15:15Life ScienceOral contributionOne of the main challenges in molecular biology is the management of data and databases. A large fraction of the biological data produced is publicly available on web sites or by ftp protocols. These public databases are internationally known and play a key role in the majority of public and private research. But their exponential growth raises an usage problem. Indeed, scientists need...Go to contribution page
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Dr Ying-Ta Wu (Academia Sinica Genomic Research Center)01/03/2006, 16:30Life ScienceOral contributionThe potential for re-emergence of influenza pandemics has been a great threat since the report of that the avian influenza A virus (H5N1) having acquired the ability to be transmitted to humans. An increase of transmission incidents suggests the risk of human-to-human transmission, and the report of development of drug resistance variants is another potential concern. At present, there are...Go to contribution page
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Mr Nicolas Jacq (CNRS/IN2P3)01/03/2006, 16:45Life ScienceOral contributionAdvance in combinatorial chemistry has paved the way for synthesizing large numbers of diverse chemical compounds. Thus there are millions of chemical compounds available in the laboratories, but it is nearly impossible and very expensive to screen such a high number of compounds in the experimental laboratories by high throughput screening (HTS). Besides the high costs, the hit rate...Go to contribution page
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Mrs Livia Torterolo (Bio-Lab, DIST, University of Genoa)01/03/2006, 17:00Life ScienceOral contributionA voxel based statistical analysis of perfusional medical images may provide powerful support to the early diagnosis for Alzheimerโs Disease (AD). A Statistical Parametric Mapping algorithm (SPM), based on the comparison of the candidate with normal cases, has been validated by the neurological research community to quantify ipometabolic patterns in brain PET/SPECT studies. Since...Go to contribution page
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Prof. Hugues BENOIT-CATTIN (CREATIS - UMR CNRS 5515 - U630 Inserm)01/03/2006, 17:15Life ScienceOral contributionIn this paper, we present a web protal that enables simulation of MRI images on the grid. Such simulations are done using the SIMRI MRI simulator that is implemented on the grid using MPI. MRI simulations are useful for better understanding the MRI physics, for studying MRI sequences (parameterisation), and validating image processing algorithms. The web portal client/server...Go to contribution page
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Dr Ignacio Blanquer (Universidad Politรฉcnica de Valencia)01/03/2006, 17:30Life ScienceOral contributionThe liver is the largest organ of the abdomen and there are a large number of lesions affecting it. Both benign and malignant tumours arise within it. The liver is also the target organ for most solid tumours metastasis. Angiogenesis is quite an important marker of tumour aggressiveness and response to therapy. The blood supply to the liver is derived jointly from the hepatic arteries and...Go to contribution page
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Prof. Victor Lakhno (IMPB RAS, Russia)01/03/2006, 17:45Life ScienceOral contributionAs recently as a few years ago a possibility of constructing a mathematical model of a life seemed absolutely fantastic. However, at the beginning of 21-th century several research teams announced creation of a minimum model of life. To be more specific, not life in general, but an elementary brick of life, that is a living cell. The most well-known of them are: USA Virtual Cell...Go to contribution page
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