Dr
Christophe Blanchet
(CNRS IBCP), Mr
Vincent Lefort
(CNRS IBCP)
01/03/2006, 14:00
Life Science
Oral contribution
One of current major challenges in the bioinformatics field is to derive valuable information from the complete
genome sequencing projects, which provide the bioinformatics community with a large number of unknown
sequences. The first prerequisite step in this process is to access up-to-date sequence and 3D-structure
databanks (EMBL, GenBank, SWISS-PROT, Protein Data Bank...) maintained...
Dr
Christophe Blanchet
(CNRS IBCP), Mr
Rémi Mollon
(CNRS IBCP)
01/03/2006, 14:15
Life Science
Oral contribution
Introduction
Biomedical applications are pilot ones in the EGEE project [1][2] and have their own virtual organization: the
“biomed” VO. Indeed, they have common security requirements such as electronic certificate system,
authentication, secured transfer; but they have also specific ones such as fine grain access to data, encrypted
storage of data and anonymity. Certificate system...
Dr
Luciano Milanesi
(National Research Council - Institute of Biomedical Technologies)
01/03/2006, 14:30
Life Science
Oral contribution
Project descriptions
The European Commission promotes the Bioinformatics Grid Application for life
science (BIOINFOGRID) project. The BIOINFOGRID project web site will be available at
http://www.itb.cnr.it/bioinfogrid.
The project aims to connect many European computer centres in order to carry out
Bioinformatics research and to develop new applications in the sector using a...
Silvano Paoli
(ITC-irst)
01/03/2006, 14:45
Life Science
Oral contribution
Abstract
BioDCV is a distributed computing system for the complete validation of gene
profiles. The system is composed of a suite of software modules that allows the
definition, management and analysis of a complete experiment on DNA microarray data.
The BioDCV system is grid-enabled on LCG/EGEE middleware in order to build
predictive
classification models and to extract the most...
Ms
Nadezhda Fialko
(research fellow)
01/03/2006, 15:00
Life Science
Oral contribution
Recently, at the interface of physics, chemistry and biology, a new and rapidly
developing research trend has emerged concerned with charge transfer in
biomacromolecules. Of special interest to researchers is the electron and hole
transfer along a chain of base pairs, since the migration of radicals over a DNA
molecule plays a crucial role in the processes of mutagenesis and...
Mr
Jean Salzemann
(IN2P3/CNRS)
01/03/2006, 15:15
Life Science
Oral contribution
One of the main challenges in molecular biology is the management of data and
databases. A large fraction of the biological data produced is publicly available on
web sites or by ftp protocols. These public databases are internationally known and
play a key role in the majority of public and private research. But their
exponential
growth raises an usage problem. Indeed, scientists need...
Dr
Ying-Ta Wu
(Academia Sinica Genomic Research Center)
01/03/2006, 16:30
Life Science
Oral contribution
The potential for re-emergence of influenza pandemics has been a great threat since
the report of that the avian influenza A virus (H5N1) having acquired the ability to
be transmitted to humans. An increase of transmission incidents suggests the risk of
human-to-human transmission, and the report of development of drug resistance
variants is another potential concern. At present, there are...
Mr
Nicolas Jacq
(CNRS/IN2P3)
01/03/2006, 16:45
Life Science
Oral contribution
Advance in combinatorial chemistry has paved the way for synthesizing large numbers
of diverse chemical compounds. Thus there are millions of chemical compounds
available in the laboratories, but it is nearly impossible and very expensive to
screen such a high number of compounds in the experimental laboratories by high
throughput screening (HTS). Besides the high costs, the hit rate...
Mrs
Livia Torterolo
(Bio-Lab, DIST, University of Genoa)
01/03/2006, 17:00
Life Science
Oral contribution
A voxel based statistical analysis of perfusional medical images may provide
powerful support to the early diagnosis for Alzheimer’s Disease (AD). A Statistical
Parametric Mapping algorithm (SPM), based on the comparison of the candidate with
normal cases, has been validated by the neurological research community to quantify
ipometabolic patterns in brain PET/SPECT studies. Since...
Prof.
Hugues BENOIT-CATTIN
(CREATIS - UMR CNRS 5515 - U630 Inserm)
01/03/2006, 17:15
Life Science
Oral contribution
In this paper, we present a web protal that enables simulation of MRI images on the
grid. Such simulations are done using the SIMRI MRI simulator that is implemented on
the grid using MPI. MRI simulations are useful for better understanding the MRI
physics, for studying MRI sequences (parameterisation), and validating image
processing algorithms. The web portal client/server...
Dr
Ignacio Blanquer
(Universidad Politécnica de Valencia)
01/03/2006, 17:30
Life Science
Oral contribution
The liver is the largest organ of the abdomen and there are a large number of lesions
affecting it. Both benign and malignant tumours arise within it. The liver is also
the target organ for most solid tumours metastasis. Angiogenesis is quite an
important marker of tumour aggressiveness and response to therapy. The blood supply
to the liver is derived jointly from the hepatic arteries and...
Prof.
Victor Lakhno
(IMPB RAS, Russia)
01/03/2006, 17:45
Life Science
Oral contribution
As recently as a few years ago a possibility of constructing a mathematical model of
a life seemed absolutely fantastic. However, at the beginning of 21-th century
several research teams announced creation of a minimum model of life. To be more
specific, not life in general, but an elementary brick of life, that is a living
cell. The most well-known of them are: USA Virtual Cell...
