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Ms Soo Mee Kim (Department of Nuclear Medicine, Seoul National University College of Medicine)09/05/2006, 14:00• Image reconstruction and processingposterIterative image reconstruction for Compton camera is computationally challenging since the projection and backprojection are performed on conical surfaces rather than along straight lines and there is a number of possible combinations of position and energy measurements. Therefore, computationally efficient implementation of a projector-backprojector pair without loss of quantitative...Go to contribution page
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Ms Leticia Ortega Maynez (School of Chemical Engineering and Analytical Science at the University of Manchester)09/05/2006, 14:00• Image reconstruction and processingposterThe very high resolution quad-HIDAC PET scanner has four detector banks each with four planar high density avalanche chambers, forming 16 modules in total. The scanner has a large field of view (FOV) of 170 mm x 170 mm x 280 mm able to do whole body rodent imaging. It has many important applications, just one example being dynamic neuroreceptor imaging in mice. However, detector...Go to contribution page
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Dr Shoji Kawatsu (Kyoritu General Hospital, National Center for Geriatrics and Gerontology)09/05/2006, 14:00• Image reconstruction and processingposterTraditionally, three dimensional (3-D) positron emission tomography (PET) image reconstruction is performed with the filtered back projection (FBP) method or the iterative reconstruction method [1,2]. These methods do not directly apply the geometrical property of lines of response (LORs) whereby two LORs, which originate from radioactive isotopes in the same position, lie within a...Go to contribution page
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Prof. Hongbing Lu (Department of Computer Application, Fourth Military Medical University, Shaanxi, China)09/05/2006, 14:00• Image reconstruction and processingposterDynamic or gated cardiac SPECT imaging has been playing a major role in evaluation of chest pain and other cardiac symptoms. Conventionally, the acquired dynamic data sequences are reconstructed frame by frame, where the temporal correlation among different frames is not utilized. In this work, we proposed a framework for analytical reconstruction in the Karhunen-Loeve (KL) domain of...Go to contribution page
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Mr Andreas Thon (Philips Research Laboratories)09/05/2006, 14:00• Modeling, sampling strategiesposterObjectives: The determination of the exact shape of the input function is a particular challenge in dynamic cardiac 82Rb PET perfusion studies. The dynamic range of the activity in these studies easily covers two orders of magnitude. Additionally, the injection bolus has a very sharp peak. The measurement of the input function depends on both experimental errors (e.g. random noise,...Go to contribution page
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Mr Ismael KARIDIOULA ((1) Centre Jean Perrin, Division of Nuclear Medicine, F-63011 Clermont-Ferrand, France, (2)University of Auvergne, Faculty of Medicine, F-63000 Clermont-Ferrand, France, (3)INSERM, U484, F-63000Clermont-Ferrand, France)09/05/2006, 14:00• Image reconstruction and processingposterAim: A new method for the automatic calculation of the mean standardized uptake value (meanSUV) in pulmonary lesions detected by FDG PET-CT has been developed and validated. Materials and methods: In PET-CT, calculation of FDG meanSUV rests on the delineation of a region of interest (ROI) around the tumor on a PET section. We propose to draw the ROI by utilizing the limits of...Go to contribution page
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Dr Carole Lartizien (Creatis laboratory, UMR CNRS 5515 et INSERM U630, Villeurbanne, France)09/05/2006, 14:00• System simulation, design and implementationposterObjectives: Recent advances in PET systems dedicated to small animal imaging have provided new ways to perform biologic research. They consecutively increased the need to develop realistic simulation models that allows optimizing acquisition and reconstruction protocols in order to improve image quantification and detection. PET-SORTEO is a Monte Carlo-based simulator that enables the fast...Go to contribution page
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Mr Roel Van Holen (Ghent University ELIS-MEDISIP)09/05/2006, 14:00• System simulation, design and implementationposterINTRODUCTION Traditional gamma camera imaging with a parallel hole collimated detector (PH) is limited by the sensitivity versus spatial resolution tradeoff which is intrinsic to the design. This results in a reduced contrast for small lesions. The higher geometrical sensitivity of a rotating slat (RS) collimated strip detector could improve the image quality considerably. By means of...Go to contribution page
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Dr Keishi Kitamura (Shimadzu Corporation)09/05/2006, 14:00• Image reconstruction and processingposterThe jPET-D4 is a brain PET scanner composed of 4-layer depth-of-interaction (DOI) detectors with a large number of GSO crystals, which achieves both high spatial resolution and high scanner sensitivity. Since the sensitivity of each crystal elements highly depends on the depth of DOI layers and the energy of an incident gamma ray, it is difficult to estimate normalization factors and...Go to contribution page
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Ms So Hyun AN (Hanyang University)09/05/2006, 14:00• System simulation, design and implementationposterThe Compton camera, which uses a new concept of collimation, i.e., electronic collimation, has a bright future as a medical imaging device considering its simplicity and inherent 3D image capability. Currently, however, the spatial resolution of the Compton camera is not sufficient for medical imaging. In this study, we investigated the effect of various parameters in Compton camera on...Go to contribution page
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Dr Magdalena Rafecas (Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia/CSIC)09/05/2006, 14:00• System simulation, design and implementationposter* Motivation: High spatial resolution and high sensitivity are mandatory in small animal PET. To achieve high resolution, pixelated crystal detectors with individual read-out are often employed. Sensitivity can be improved by reducing the scanner diameter, and also by lowering the low energy threshold (LET). The latter allows photons which undergo Compton interactions in the object or in...Go to contribution page
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Mr Vyacheslav Pedash (Institute for scintillation materials NAS of Ukraine)09/05/2006, 14:00• System simulation, design and implementationposterGamma-camera use for a breast imaging (Scinti-Mammography) is a quite difficult task because of specific geometry. Edge artefact is the main problem that should be solved in imaging system. Reduced FOV near edges relates to scintillation detector non uniformity and image reconstruction problems. The scale of the “dead zone” usually corresponds to the half of the PMT size used with detector...Go to contribution page
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Dr Vyacheslav Vinogradov (Institute for Nuclear Reserarch RAS)09/05/2006, 14:00• System simulation, design and implementationposterThere are a lot of tasks in medicine, engineering and industry, where normal and critical states of some objects can be monitoring, recognized and registered as event signals in real time for analysis. Event recognition and registration of abnormal signals can be used to study of objects before and during its abnormal states or to predict its risk situations. Recognition and...Go to contribution page
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Mr Ivan Valastyan (Institute of Nuclear Research of the Hungarian Academy of Sciences, Debrecen, Hungary Royal Institute of Technology, Stockholm, Sweden)09/05/2006, 14:00• Modeling, sampling strategiesposterIterative reconstruction methods are commonly used to obtain images with high resolution and good signal-to-noise ratio in nuclear imaging. The aim of this work was to develop a scalable, fast, cluster based, fully 3D iterative image reconstruction package for our small animal PET camera, the miniPET. The miniPET scanner consists of four detector blocks mounted on a rotatable gantry....Go to contribution page
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Mr Nam Young Kim (Department of Physics, Chung-Ang University, Seoul 156-756, Republic of Korea)09/05/2006, 14:00• System simulation, design and implementationposterA Compton camera has excellent imaging and spectroscopic characteristics which can fulfill the requirements in various fields such as biomedical research, nuclear medicine, astrophysics, and national security. Especially its high imaging sensitivity is the most fascinating aspect to nuclear medical imaging fields. According to our previous works related to the performance of a...Go to contribution page
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Dr Brigitte Gundlich (Forschungszentrum Jülich GmbH)09/05/2006, 14:00• System simulation, design and implementationposterClearPET(TM) Neuro is a small animal PET scanner dedicated to brain studies on rats and primates. It belongs to the ClearPET family of small animal PET scanners that are developed within the Crystal Clear Collaboration (CERN) and use the same detector block design with LSO and LuYAP crystals in phoswich configuration, directly coupled with multi-anode photomultiplier tubes. ...Go to contribution page
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Mr Yung-Hui Huang (National Yang-Ming University)09/05/2006, 14:00• System performance seen by the users, dose reductionposterCardiovascular diseases are the most common incidence for premature death in developed countries. A major fraction is attributable to atherosclerotic coronary artery disease which may result in sudden cardiac failure. A reduction of mortality caused by myocardial infarction may be achieved if coronary atherosclerosis can be detected and treated at an early stage before symptoms occur....Go to contribution page
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Dr Eiji Yoshida (National Institute of Radiological Sciences)09/05/2006, 14:00• Image reconstruction and processingposterIn a conventional PET detector, detected events are projected to 2D position histogram with Anger calculation for a crystal identification. However, the measured histogram is affected by inter-crystal scatterings (ICS) which occur in a whole detector. Peaks with projected each crystal in the histogram are blurred, and it causes ICS’s mispositioning. A depth of interaction (DOI) detector...Go to contribution page
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Mr junichi ohi (shimadzu)09/05/2006, 14:00• System simulation, design and implementationposterRecently, small animal depth of interaction (DOI) PET systems are being researched and developed in a variety of laboratories and companies. In this study, we were conducting basic research on a whole-body DOI-PET system which provides spatial resolution that is both high and uniform, and also minimizes costs. The detectors used consist of double-layer 9×10 GSO/GSO crystal blocks, a...Go to contribution page
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Mr Nikolaos Efthimiou (Department of medical instrumentation-Technological educational insitution)09/05/2006, 14:00• System simulation, design and implementationposterComputer simulation modeling has been proved as a reliable and promising technique for the evaluation of the performance of medical imaging systems. The purpose of the present work was to model modern X-ray detection system and to investigate the effect of scintillator material on the detector's output signal and the image quality. The scintillators were used in the form of screens...Go to contribution page
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Mrs Solene Valton (CREATIS)09/05/2006, 14:00• Image reconstruction and processingposterBiological research on small animals is constantly demanding for imaging devices with higher performances. Innovative micro-scanners are being developed in particular to enable combined acquisition of anatomical and molecular data. In this framework, we consider the idea of using the hybrid pixel detectors with the ClearPET (see poster " PIXSCAN: Pixel Detector CT-Scanner for Small Animal...Go to contribution page
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Martin Rey (LPHE, EPFL)09/05/2006, 14:00• System simulation, design and implementationposterPositron Emission Tomography (PET) applied to small animal imaging is a potentially important tool in developing new drugs and imaging gene expression. The Crystal Clear Collaboration (CCC) is developing a new family of small animal PET scanners called ClearPET, which are based on LSO/LuYAP Depth-Of-Interaction (DOI) sensitive detector modules. In parallel, GATE, a new Monte Carlo...Go to contribution page
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Ms Nathalie DUFOUR (PhD Student - Centre Léon Bérard)09/05/2006, 14:00• System simulation, design and implementationposterHeavy charged particles like protons or light atom nuclei like carbon ions have interesting ballistic properties in cancer therapy. When used as projectiles, their electromagnetic interaction with matter is characterized with an energy loss spectrum peaking at a localized penetration depth: the so called Bragg peak. However, projectile particles used in hadrontherapy have sufficient...Go to contribution page
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Dr Dimitrios Nikolopoulos (Department of medical instrumentation-Tchnological educational insitution)09/05/2006, 14:00• System simulation, design and implementationposterRadiation transport phenomena have been extensively studied by application of the Monte Carlo technique. This was proven to be by far the most successful technique for the simulation of the stochastic processes involved in radiation detection. During the last decade, various Monte Carlo simulation packages have become commercially available, however constrained by expediency and...Go to contribution page
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Dr Yuemin ZHU (CREATIS, CNRS UMR5515 & INSERM U630, Lyon)09/05/2006, 14:00• Image reconstruction and processingposterPartial k-space acquisition is usually employed in magnetic resonance imaging (MRI) for reducing imaging time while maintaining image quality. In this field, image reconstruction from the incomplete k-space is an important matter. A number of reconstruction methods have been reported in the literature, but all these methods do not cope with truncation artifacts. We present a method...Go to contribution page
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Dr Zhi-Feng Huang (Dept. of Engineering Physics, Tsinghua Univ., China)09/05/2006, 14:00• Image reconstruction and processingposterX-ray diffraction enhanced imaging (DEI) has extremely high sensitivity and resolution of weakly absorbing low-Z samples, so it becomes an effective method for molecular imaging recently, especially in the medical and biological fields. Many experiments have been performed and high-resolution phase-contrast images of many elaborate details of the samples, such as human breast cancers...Go to contribution page
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Dr Lionel Hervé (LETI - CEA Recherche Technologique)09/05/2006, 14:00• Image reconstruction and processingposterNear-infrared fluorescence-enhanced Diffuse Optical Tomography (fDOT) has been proven to be an efficient tool for image reconstruction of the bio-distribution of fluorescent markers. By labeling regions of interest such as tumors with target- specific fluorescing molecular probes, fDOT enables both the three-dimensional (3D) localization of the targeted areas and the quantization of the...Go to contribution page
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Ms Esther Vicente Torrico (Hopital General Universitario Gregorio Marañón), Mr Joaquín López Herraiz (Universidad Complutense de Madrid), Mr Samuel España Palomares (Universidad Complutense de Madrid)09/05/2006, 14:00• System simulation, design and implementationposterPENELOPE is a code for Monte Carlo simulations of the transport in matter of electrons, positrons and photons with energies from a few hundred of eV to 1 GeV. It is robust, fast and very accurate, but it may be unfriendly for people not acquainted with the fortran prograaming language. We have developed an easy to run application that allows complete simulations for PET and SPECT with...Go to contribution page
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Dr Miklos Emri (PET Center, University of Debrecen)09/05/2006, 14:00• Image reconstruction and processingposterPractical engineering aspects of the next generation nuclear medicine detectors with Ethernet based data transfer entrust the solution of high speed data acquisition, real time event processing and data storing to software developers. In response to this challenge, a new cluster based data acquisition library (DAQ) was elaborated as part of a complex, object oriented, platform...Go to contribution page
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Dr Antonello Spinelli (Policlinico S. Orsola-Malpighi, Bologna, Italy)09/05/2006, 14:00• System performance seen by the users, dose reductionposterIntroduction The main objective of this work was to characterize the physical performance of a small animal PET scanner (GE eXplore Vista). The detector modules of the eXplore Vista consists of an 13 x 13 array of 1.45 mm square “phoswich” elements providing depth-of-interaction information. Each element is made of two scintillator crystal layers of Lutetium Yttrium Orthosilicate...Go to contribution page
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Dr Dennis R. Schaart (Delft University of Technology)09/05/2006, 14:00• System simulation, design and implementationposterIn recent years, small-animal positron emission tomography (PET) has gained much interest. Most current designs use small scintillation crystals coupled to position- sensitive photomultiplier tubes. It would seem relatively straightforward to increase the resolution in such designs by decreasing the pixel size. However, this results in loss of sensitivity because of the increased dead...Go to contribution page
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Dr Pedro Guerra09/05/2006, 14:00• Image reconstruction and processingposterWe have studied certain properties of the maximum likelihood expectation maximization (ML-EM) algorithm for iterative image reconstruction in positron emission tomography (PET). The principal aim of the work has been the development and evaluation a new stopping criterion for this algorithm. We developed and used a software platform based on Monte-Carlo techniques, which simulates the...Go to contribution page
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Ms Marie-Charlotte RICOL (Institut de physique nucléaire de Lyon (IPNL) - Université Claude Bernard Lyon 1 (UCBL))09/05/2006, 14:00• System simulation, design and implementationposterHeavy charged particles like protons or light atom nuclei like carbon ions have interesting ballistic properties in cancer therapy. When used as projectiles, their electromagnetic interaction with matter is characterized with an energy loss spectrum peaking at a localized penetration depth: the so called Bragg peak. This feature, combined with a raster scanned beam modulated in energy...Go to contribution page
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Mr JOAQUIN LOPEZ HERRAIZ (UNIVERSIDAD COMPLUTENSE DE MADRID)09/05/2006, 14:00• System simulation, design and implementationposterThe design of current small animal PET tomographs, with open geometries and extended field of view (FOV), tries to optimize sensitivity, what makes them to be particularly prone to random coincidences. Particularly in 3D mode, random counts are an important contribution to measured events. The effect of accidental coincidences in the noise equivalent counts (NEC) of an acquisition...Go to contribution page
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Mr Niklas Rehfeld (Section for Biomedical Physics, Radiooncology, University of Tuebingen)09/05/2006, 14:00• Image reconstruction and processingposterMonte Carlo (MC) simulations in positron emission tomography (PET) play an important role in detector modeling and algorithm testing. Whereas the simulations are widely used in a forward projection manner to accomplish this task, ideally they should be included into the reconstruction process itself. It is therefore desirable to investigate the convergence properties and the...Go to contribution page
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Mr Panagiotis Gonias (Department of Medical Physics, School of Medicine, university of Patras,Patra,Greece)09/05/2006, 14:00• System simulation, design and implementationposterThe recently developed GATE, a Geant4 Application for Tomographic Emission, is a Monte Carlo simulation platform developed for PET and SPECT and is freely distributed by the OpenGATE collaboration. GATE is based on a powerful simulation core, Geant4 toolkit, that includes well-validated physics models, geometry modeling tools and efficient visualization utilities, and, uses newly developed...Go to contribution page
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Dr Elisabetta De Bernardi (Bioengineering Department, Polytechnic University of Milan, Milan, Italy)09/05/2006, 14:00• Image reconstruction and processingposterINTRODUCTION: Fourier Rebinning (FORE) [1] is the most widely used algorithm for the rebinning of 3D PET data into a stack of 2D sinograms. FORE operates into the sinogram Fourier Transform domain and it is based on the frequency-distance relation. The validity of this approximation holds at high frequencies; low angular, k, and radial, ω, frequencies are instead usually rebinned with...Go to contribution page
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