Ms
Soo Mee Kim
(Department of Nuclear Medicine, Seoul National University College of Medicine)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Iterative image reconstruction for Compton camera is computationally challenging
since the projection and backprojection are performed on conical surfaces rather
than along straight lines and there is a number of possible combinations of
position and energy measurements. Therefore, computationally efficient
implementation of a projector-backprojector pair without loss of quantitative...
Ms
Leticia Ortega Maynez
(School of Chemical Engineering and Analytical Science at the University of Manchester)
09/05/2006, 14:00
• Image reconstruction and processing
poster
The very high resolution quad-HIDAC PET scanner has four detector banks each with
four planar high density avalanche chambers, forming 16 modules in total. The
scanner has a large field of view (FOV) of 170 mm x 170 mm x 280 mm able to do
whole body rodent imaging. It has many important applications, just one example
being dynamic neuroreceptor imaging in mice. However, detector...
Dr
Shoji Kawatsu
(Kyoritu General Hospital, National Center for Geriatrics and Gerontology)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Traditionally, three dimensional (3-D) positron emission tomography (PET) image
reconstruction is performed with the filtered back projection (FBP) method or the
iterative reconstruction method [1,2]. These methods do not directly apply the
geometrical property of lines of response (LORs) whereby two LORs, which originate
from radioactive isotopes in the same position, lie within a...
Prof.
Hongbing Lu
(Department of Computer Application, Fourth Military Medical University, Shaanxi, China)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Dynamic or gated cardiac SPECT imaging has been playing a major role in evaluation
of chest pain and other cardiac symptoms. Conventionally, the acquired dynamic data
sequences are reconstructed frame by frame, where the temporal correlation among
different frames is not utilized. In this work, we proposed a framework for
analytical reconstruction in the Karhunen-Loeve (KL) domain of...
Mr
Andreas Thon
(Philips Research Laboratories)
09/05/2006, 14:00
• Modeling, sampling strategies
poster
Objectives: The determination of the exact shape of the input function is a
particular challenge in dynamic cardiac 82Rb PET perfusion studies. The dynamic
range of the activity in these studies easily covers two orders of magnitude.
Additionally, the injection bolus has a very sharp peak. The measurement of the
input function depends on both experimental errors (e.g. random noise,...
Mr
Ismael KARIDIOULA
((1) Centre Jean Perrin, Division of Nuclear Medicine, F-63011 Clermont-Ferrand, France, (2)University of Auvergne, Faculty of Medicine, F-63000 Clermont-Ferrand, France, (3)INSERM, U484, F-63000Clermont-Ferrand, France)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Aim:
A new method for the automatic calculation of the mean standardized uptake value
(meanSUV) in pulmonary lesions detected by FDG PET-CT has been developed and
validated.
Materials and methods:
In PET-CT, calculation of FDG meanSUV rests on the delineation of a region of
interest (ROI) around the tumor on a PET section. We propose to draw the ROI by
utilizing the limits of...
Dr
Carole Lartizien
(Creatis laboratory, UMR CNRS 5515 et INSERM U630, Villeurbanne, France)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Objectives: Recent advances in PET systems dedicated to small animal imaging have
provided new ways to perform biologic research. They consecutively increased the need
to develop realistic simulation models that allows optimizing acquisition and
reconstruction protocols in order to improve image quantification and detection.
PET-SORTEO is a Monte Carlo-based simulator that enables the fast...
Mr
Roel Van Holen
(Ghent University ELIS-MEDISIP)
09/05/2006, 14:00
• System simulation, design and implementation
poster
INTRODUCTION
Traditional gamma camera imaging with a parallel hole collimated detector (PH) is
limited by the sensitivity versus spatial resolution tradeoff which is intrinsic to
the design. This results in a reduced contrast for small lesions. The higher
geometrical sensitivity of a rotating slat (RS) collimated strip detector could
improve the image quality considerably.
By means of...
Dr
Keishi Kitamura
(Shimadzu Corporation)
09/05/2006, 14:00
• Image reconstruction and processing
poster
The jPET-D4 is a brain PET scanner composed of 4-layer depth-of-interaction (DOI)
detectors with a large number of GSO crystals, which achieves both high spatial
resolution and high scanner sensitivity. Since the sensitivity of each crystal
elements highly depends on the depth of DOI layers and the energy of an incident
gamma ray, it is difficult to estimate normalization factors and...
Ms
So Hyun AN
(Hanyang University)
09/05/2006, 14:00
• System simulation, design and implementation
poster
The Compton camera, which uses a new concept of collimation, i.e., electronic
collimation, has a bright future as a medical imaging device considering its
simplicity and inherent 3D image capability. Currently, however, the spatial
resolution of the Compton camera is not sufficient for medical imaging. In this
study, we investigated the effect of various parameters in Compton camera on...
Dr
Magdalena Rafecas
(Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia/CSIC)
09/05/2006, 14:00
• System simulation, design and implementation
poster
* Motivation:
High spatial resolution and high sensitivity are mandatory in small animal PET. To
achieve high resolution, pixelated crystal detectors with individual read-out are
often employed. Sensitivity can be improved by reducing the scanner diameter, and
also by lowering the low energy threshold (LET). The latter allows photons which
undergo Compton interactions in the object or in...
Mr
Vyacheslav Pedash
(Institute for scintillation materials NAS of Ukraine)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Gamma-camera use for a breast imaging (Scinti-Mammography) is a quite difficult task
because of specific geometry. Edge artefact is the main problem that should be solved
in imaging system. Reduced FOV near edges relates to scintillation detector non
uniformity and image reconstruction problems. The scale of the “dead zone” usually
corresponds to the half of the PMT size used with detector...
Dr
Vyacheslav Vinogradov
(Institute for Nuclear Reserarch RAS)
09/05/2006, 14:00
• System simulation, design and implementation
poster
There are a lot of tasks in medicine, engineering and industry, where normal and
critical states of some objects can be monitoring, recognized and registered as
event signals in real time for analysis. Event recognition and registration of
abnormal signals can be used to study of objects before and during its abnormal
states or to predict its risk situations. Recognition and...
Mr
Ivan Valastyan
(Institute of Nuclear Research of the Hungarian Academy of Sciences, Debrecen, Hungary Royal Institute of Technology, Stockholm, Sweden)
09/05/2006, 14:00
• Modeling, sampling strategies
poster
Iterative reconstruction methods are commonly used to obtain images with high
resolution and good signal-to-noise ratio in nuclear imaging. The aim of this work
was to develop a scalable, fast, cluster based, fully 3D iterative image
reconstruction package for our small animal PET camera, the miniPET.
The miniPET scanner consists of four detector blocks mounted on a rotatable gantry....
Mr
Nam Young Kim
(Department of Physics, Chung-Ang University, Seoul 156-756, Republic of Korea)
09/05/2006, 14:00
• System simulation, design and implementation
poster
A Compton camera has excellent imaging and spectroscopic characteristics which can
fulfill the requirements in various fields such as biomedical research, nuclear
medicine, astrophysics, and national security. Especially its high imaging
sensitivity is the most fascinating aspect to nuclear medical imaging fields.
According to our previous works related to the performance of a...
Dr
Brigitte Gundlich
(Forschungszentrum Jülich GmbH)
09/05/2006, 14:00
• System simulation, design and implementation
poster
ClearPET(TM) Neuro is a small animal PET scanner dedicated to brain studies on rats
and primates. It belongs to the ClearPET family of small animal PET scanners
that are developed within the Crystal Clear Collaboration (CERN) and use the same
detector block design with LSO and LuYAP crystals in phoswich configuration,
directly coupled with multi-anode photomultiplier tubes. ...
Mr
Yung-Hui Huang
(National Yang-Ming University)
09/05/2006, 14:00
• System performance seen by the users, dose reduction
poster
Cardiovascular diseases are the most common incidence for premature death in
developed countries. A major fraction is attributable to atherosclerotic coronary
artery disease which may result in sudden cardiac failure. A reduction of mortality
caused by myocardial infarction may be achieved if coronary atherosclerosis can be
detected and treated at an early stage before symptoms occur....
Dr
Eiji Yoshida
(National Institute of Radiological Sciences)
09/05/2006, 14:00
• Image reconstruction and processing
poster
In a conventional PET detector, detected events are projected to 2D position
histogram with Anger calculation for a crystal identification. However, the measured
histogram is affected by inter-crystal scatterings (ICS) which occur in a whole
detector. Peaks with projected each crystal in the histogram are blurred, and it
causes ICS’s mispositioning. A depth of interaction (DOI) detector...
Mr
junichi ohi
(shimadzu)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Recently, small animal depth of interaction (DOI) PET systems are being researched
and developed in a variety of laboratories and companies. In this study, we were
conducting basic research on a whole-body DOI-PET system which provides spatial
resolution that is both high and uniform, and also minimizes costs. The detectors
used consist of double-layer 9×10 GSO/GSO crystal blocks, a...
Mr
Nikolaos Efthimiou
(Department of medical instrumentation-Technological educational insitution)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Computer simulation modeling has been proved as a reliable and promising technique
for the evaluation of the performance of medical imaging systems. The purpose of the
present work was to model modern X-ray detection system and to investigate the effect
of scintillator material on the detector's output signal and the image quality. The
scintillators were used in the form of screens...
Mrs
Solene Valton
(CREATIS)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Biological research on small animals is constantly demanding for imaging devices with
higher performances. Innovative micro-scanners are being developed in particular to
enable combined acquisition of anatomical and molecular data. In this framework, we
consider the idea of using the hybrid pixel detectors with the ClearPET (see poster "
PIXSCAN: Pixel Detector CT-Scanner for Small Animal...
Martin Rey
(LPHE, EPFL)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Positron Emission Tomography (PET) applied to small animal imaging is a potentially
important tool in developing new drugs and imaging gene expression. The Crystal Clear
Collaboration (CCC) is developing a new family of small animal PET scanners called
ClearPET, which are based on LSO/LuYAP Depth-Of-Interaction (DOI) sensitive detector
modules. In parallel, GATE, a new Monte Carlo...
Ms
Nathalie DUFOUR
(PhD Student - Centre Léon Bérard)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Heavy charged particles like protons or light atom nuclei like carbon ions have
interesting ballistic properties in cancer therapy. When used as projectiles,
their electromagnetic interaction with matter is characterized with an energy loss
spectrum peaking at a localized penetration depth: the so called Bragg peak.
However, projectile particles used in hadrontherapy have sufficient...
Dr
Dimitrios Nikolopoulos
(Department of medical instrumentation-Tchnological educational insitution)
09/05/2006, 14:00
• System simulation, design and implementation
poster
Radiation transport phenomena have been extensively studied by application of the
Monte Carlo technique. This was proven to be by far the most successful technique for
the simulation of the stochastic processes involved in radiation detection. During
the last decade, various Monte Carlo simulation packages have become commercially
available, however constrained by expediency and...
Dr
Yuemin ZHU
(CREATIS, CNRS UMR5515 & INSERM U630, Lyon)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Partial k-space acquisition is usually employed in magnetic resonance imaging (MRI)
for reducing imaging time while maintaining image quality. In this field, image
reconstruction from the incomplete k-space is an important matter. A number of
reconstruction methods have been reported in the literature, but all these methods
do not cope with truncation artifacts. We present a method...
Dr
Zhi-Feng Huang
(Dept. of Engineering Physics, Tsinghua Univ., China)
09/05/2006, 14:00
• Image reconstruction and processing
poster
X-ray diffraction enhanced imaging (DEI) has extremely high sensitivity and
resolution of weakly absorbing low-Z samples, so it becomes an effective method for
molecular imaging recently, especially in the medical and biological fields. Many
experiments have been performed and high-resolution phase-contrast images of many
elaborate details of the samples, such as human breast cancers...
Dr
Lionel Hervé
(LETI - CEA Recherche Technologique)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Near-infrared fluorescence-enhanced Diffuse Optical Tomography (fDOT) has been
proven to be an efficient tool for image reconstruction of the bio-distribution of
fluorescent markers. By labeling regions of interest such as tumors with target-
specific fluorescing molecular probes, fDOT enables both the three-dimensional (3D)
localization of the targeted areas and the quantization of the...
Ms
Esther Vicente Torrico
(Hopital General Universitario Gregorio Marañón), Mr
Joaquín López Herraiz
(Universidad Complutense de Madrid), Mr
Samuel España Palomares
(Universidad Complutense de Madrid)
09/05/2006, 14:00
• System simulation, design and implementation
poster
PENELOPE is a code for Monte Carlo simulations of the transport in matter of
electrons, positrons and photons with energies from a few hundred of eV to 1 GeV. It
is robust, fast and very accurate, but it may be unfriendly for people not acquainted
with the fortran prograaming language.
We have developed an easy to run application that allows complete simulations for PET
and SPECT with...
Dr
Miklos Emri
(PET Center, University of Debrecen)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Practical engineering aspects of the next generation nuclear medicine detectors with
Ethernet based data transfer entrust the solution of high speed data acquisition,
real time event processing and data storing to software developers. In response to
this challenge, a new cluster based data acquisition library (DAQ) was elaborated
as part of a complex, object oriented, platform...
Dr
Antonello Spinelli
(Policlinico S. Orsola-Malpighi, Bologna, Italy)
09/05/2006, 14:00
• System performance seen by the users, dose reduction
poster
Introduction
The main objective of this work was to characterize the physical performance of a
small animal PET scanner (GE eXplore Vista). The detector modules of the eXplore
Vista consists of an 13 x 13 array of 1.45 mm square “phoswich” elements providing
depth-of-interaction information. Each element is made of two scintillator crystal
layers of Lutetium Yttrium Orthosilicate...
Dr
Dennis R. Schaart
(Delft University of Technology)
09/05/2006, 14:00
• System simulation, design and implementation
poster
In recent years, small-animal positron emission tomography (PET) has gained much
interest. Most current designs use small scintillation crystals coupled to position-
sensitive photomultiplier tubes. It would seem relatively straightforward to increase
the resolution in such designs by decreasing the pixel size. However, this results in
loss of sensitivity because of the increased dead...
Dr
Pedro Guerra
09/05/2006, 14:00
• Image reconstruction and processing
poster
We have studied certain properties of the maximum likelihood expectation
maximization (ML-EM) algorithm for iterative image reconstruction in positron
emission tomography (PET). The principal aim of the work has been the development
and evaluation a new stopping criterion for this algorithm. We developed and used a
software platform based on Monte-Carlo techniques, which simulates the...
Ms
Marie-Charlotte RICOL
(Institut de physique nucléaire de Lyon (IPNL) - Université Claude Bernard Lyon 1 (UCBL))
09/05/2006, 14:00
• System simulation, design and implementation
poster
Heavy charged particles like protons or light atom nuclei like carbon ions have
interesting ballistic properties in cancer therapy. When used as projectiles,
their electromagnetic interaction with matter is characterized with an energy loss
spectrum peaking at a localized penetration depth: the so called Bragg peak. This
feature, combined with a raster scanned beam modulated in energy...
Mr
JOAQUIN LOPEZ HERRAIZ
(UNIVERSIDAD COMPLUTENSE DE MADRID)
09/05/2006, 14:00
• System simulation, design and implementation
poster
The design of current small animal PET tomographs, with open geometries and
extended field of view (FOV), tries to optimize sensitivity, what makes them to be
particularly prone to random coincidences. Particularly in 3D mode, random counts
are an important contribution to measured events.
The effect of accidental coincidences in the noise equivalent counts (NEC) of an
acquisition...
Mr
Niklas Rehfeld
(Section for Biomedical Physics, Radiooncology, University of Tuebingen)
09/05/2006, 14:00
• Image reconstruction and processing
poster
Monte Carlo (MC) simulations in positron emission tomography (PET) play an important
role in detector modeling and algorithm testing. Whereas the simulations are widely
used in a forward projection manner to accomplish this task, ideally they should be
included into the reconstruction process itself. It is therefore desirable to
investigate the convergence properties and the...
Mr
Panagiotis Gonias
(Department of Medical Physics, School of Medicine, university of Patras,Patra,Greece)
09/05/2006, 14:00
• System simulation, design and implementation
poster
The recently developed GATE, a Geant4 Application for Tomographic Emission, is a
Monte Carlo simulation platform developed for PET and SPECT and is freely distributed
by the OpenGATE collaboration. GATE is based on a powerful simulation core, Geant4
toolkit, that includes well-validated physics models, geometry modeling tools and
efficient visualization utilities, and, uses newly developed...
Dr
Elisabetta De Bernardi
(Bioengineering Department, Polytechnic University of Milan, Milan, Italy)
09/05/2006, 14:00
• Image reconstruction and processing
poster
INTRODUCTION: Fourier Rebinning (FORE) [1] is the most widely used algorithm for
the rebinning of 3D PET data into a stack of 2D sinograms. FORE operates into the
sinogram Fourier Transform domain and it is based on the frequency-distance
relation. The validity of this approximation holds at high frequencies; low
angular, k, and radial, ω, frequencies are instead usually rebinned with...
