21–25 Sept 2009
Institut des Cordeliers 15, rue de l'Ecole de Médecine (Métro Odéon) Paris, France
Europe/Paris timezone
<strong>The deadline for paper submission has been extended to 23 October 2009</strong>

Data acquisition system for a proton imaging apparatus

22 Sept 2009, 11:00
25m
Institut des Cordeliers 15, rue de l'Ecole de Médecine (Métro Odéon) Paris, France

Institut des Cordeliers 15, rue de l'Ecole de Médecine (Métro Odéon) Paris, France

Oral Systems, installation and commissioning Parallel session B1 - Systems, Installation and Commissioning

Speaker

Dr Valeria Sipala (Dipartimento di Fisica - Università degli Studi di Catania & INFN sez Catania)

Description

New developments in the proton-therapy field for cancer treatments, leaded Italian physics researchers to realize a proton imaging apparatus consisting of a silicon microstrip tracker, to reconstruct the proton trajectories, and a calorimeter, to measure their residual energy. For clinical requirements, the detectors used and the data acquisition system should be able to sustain 1 MHz proton rate. The tracker read-out, using an ASICs, acquires the signals detector and sends data in parallel to an FPGA. The YAG:Ce calorimeter generates also the global trigger. The data acquisition system and the results obtained with a 60MeV proton beam are presented and discussed

Summary

The proton therapy is a good clinical treatment for cancer as it permits to obtain a dose distribution extremely conform to the target volume. In order to fully exploit the potential of proton dose release, the dose calculation should be performed with high accuracy. This issue requires the knowledge of proton stopping power inside the tissues. Up to now this information is deduced from X-Rays Computed Tomography, but the error related to this procedure is relevant. To overcome this problem, proton imaging can be used as a direct method for stopping power determination. Moreover, the same imaging system can be useful in the patient positioning verification. The aim of the project is to develop a proton imaging system with density and spatial resolution less than 1% and 1 mm respectively. The apparatus that will be presented reconstructs the map of the electron density by tracking the single proton through the traversed tissue and by measuring its residual energy. In order to cross the entire patient thickness, proton energy must be 200-250MeV . The need for tracking the single particle derives from the Coulomb multiple scattering of protons inside the matter. In order to acquire an image in a fraction of a second, following clinical requirements, the system should be able to sustain 1MHz proton beam. Our apparatus includes a tracker with eight x-y planes based on position sensitive microstrip detectors to determine particle entry and exit point and direction. Downstream the tracker, a calorimeter is used for residual energy measurement. Each tracker plane consists of two module with sensors positioned at 90° to each other. The tracker module includes a front-end board and a digital board. The microstrip silicon detector, positioned in the front-end board, is coupled with eight ASICs each serving 32 front-end channels. The integrated circuit, developed by the collaboration, via a charge sensitive amplifier, a shaper and a comparator, converts the fast current signal from the microstrip crossed by the particle, in a digital pulse of 300-800ns. The duration of the pulse depends on the amount of energy released by the proton and on the threshold value used. So, for fixed threshold value, by the Time Over Threshold (TOT) technique it is possible also to measure the charge released into the silicon detector. The outputs signals are sent in parallel to an FPGA located on the digital board which performs zero suppression and moves data to a buffer memory. An Ethernet commercial module is use both for data transfer to the central acquisition PC and to control the tracker module DAQ parameters. Results about a single plane test performed at Laboratori Nazionali del Sud (LNS) with 60MeV proton beam will be presented. The calorimeter consists of four YAG:Ce scintillating crystals, coupled with commercial photodiodes. The read-out system acquires the information about the residual energy of the particle and generates the trigger signal and the system global event number. Thanks to the fast scintillating light decay constant the YAG:Ce crystal is able to sustain 1MHz proton rate. This apparatus was tested with 60MeV and 200MeV proton beams at LNS and Loma Linda University Medical Center (LLMC) respectively. Data analysis shows that this crystal meets high and spatially-uniform efficiency and energy resolution requirements.

Primary author

Dr Valeria Sipala (Dipartimento di Fisica - Università degli Studi di Catania & INFN sez Catania)

Co-authors

Dr Carlo Civinini (INFN sez Firenze) Dr Cinzia Talamonti (Dipartimento di Fisiopatologia Clinica - Università degli Studi di Firenze & INFN sez Firenze) Ms Concetta Stancampiano (Dipartimento di Fisica - Università degli Studi di Catania & INFN sez Catania) Dr David Menichelli (Dipartimento di Energetica - Università degli Studi di Firenze & INFN sez Firenze) Dr Domenico Lo Presti (Dipartimento di Fisica - Università degli Studi di Catania & INFN sez Catania) Dr Enrico Mazzaglia (INFN - Laboratori Nazionali del Sud) Dr Giacomo Cuttone (INFN - Laboratori Nazionali del Sud) Dr Giuliana Candiano (INFN - Laboratori Nazionali del Sud) Dr Giuseppe Antonio Pablo Cirrone (INFN - Laboratori Nazionali del Sud) Dr Livia Marrazzo (Dipartimento di Fisiopatologia Clinica - Università degli Studi di Firenze & INFN sez Firenze) Prof. Lorenzo Capineri (Dipartimento di Elettronica e Telecomunicazioni - Università degli Studi di Firenze) Prof. Mara Bruzzi (Dipartimento di Energetica - Università degli Studi di Firenze & INFN sez Firenze) Prof. Marta Bucciolini (Dipartimento di Fisiopatologia Clinica - Università degli Studi di Firenze & INFN sez Firenze) Mr Mauro Tesi (Dipartimento di Energetica - Università degli Studi di Firenze) Dr Nunzio Randazzo (INFN sez Catania) Dr Samuela Valentini (Dipartimento di Elettronica e Telecomunicazioni - Università degli Studi di Firenze & INFN sez Firenze) Dr Stefano Pieri (Dipartimento di Energetica - Università degli Studi di Firenze & INFN sez Firenze)

Presentation materials