2-7 June 2019
Simon Fraser University
America/Vancouver timezone
Welcome to the 2019 CAP Congress Program website! / Bienvenue au siteweb du programme du Congrès de l'ACP 2019 !

90 - Atmospheric plume dynamics of a picosecond infrared laser with applications in surgery and biodiagnostics with mass spectrometry

4 Jun 2019, 16:53
2m
SWH 9082 + AQ South-East Corner / coin sud-est (Simon Fraser University)

SWH 9082 + AQ South-East Corner / coin sud-est

Simon Fraser University

Poster Competition (Undergraduate Student) / Compétition affiches (Étudiant(e) du 1er cycle) Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB) DPMB Poster Session & Student Poster Competition Finals (4) | Session d'affiches DPMB et finales du concours d'affiches étudiantes (4)

Speaker

Ms Esther Yung Huei Lin

Description

In principle, lasers allow surgery at the single cell limit. But in practice, shock waves and thermal damage still pose problems. We have employed a picosecond infrared laser lasing at the water absorption peak at 3um to excite water molecules under desorption by impulsive vibrational excitation, leading to ablation processes faster than thermal and acoustic energy transfers. This rapid process greatly reduces the amount of scar tissue when compared to incisions made with scalpels or conventional medical lasers. By selectively exciting the water molecules, intact functional biological entities can be extracted and used for biodiagnostics with mass spectrometry. The combination of rapid ablations and molecule extractions allow for real-time molecular feedback during surgery. The ablation process consists of shock front expansions and material ejections that result in a plume. These nanosecond-long dynamics are captured using bright-field microscopy, allowing us to extract the velocity of the shockwave through images captured at different timings. We observe and characterize plume shapes as a function of laser fluences and material, some of which are liquid water, ice, liquid acetone, and liquid toluene.

Primary author

Ms Esther Yung Huei Lin

Presentation Materials