4–6 Sept 2019
CNA Seville
Europe/Madrid timezone

Spectrum and flux measurements of secondary ultra-fast neutrons produced in Particle Therapy treatments using the innovative MONDO tracker.

Not scheduled
1h 30m
Salón de Actos (CNA Seville)

Salón de Actos

CNA Seville

Venida Thomas Alva Edison n º 7 Parque Tecnológico Cartuja '93 E‐41092 Seville – Spain

Speaker

Mrs Micol De Simoni (Università di Roma "La Sapienza", Fisica, Rome, Italy)

Description

The secondary neutrons produced in Particle Therapy treatments can travel along the path inside the patient and contribute with additional dose in-and out-of-field. This unwanted dose increases the risk of developing secondary cancers: late insurgences are particularly crucial in paediatric patients where the closeness of the organs and the recurrence onset strongly impacts the life expectation and quality [1].
A precise measurements of neutron flux, spectra and angular distributions is eagerly needed so to predict the normal tissue toxicity in the target region and the risk of late complications in the whole body.
Nowadays, no existing detector is able to separate efficiently the secondary neutrons from the ternary neutral component generated in the iterative interactions of fragmentation products with the treatment room (walls, nozzle, etc…) and the patient itself.
MONDO is a tracker tailored for the ultra-fast neutron detection in the [20-400] MeV energy range [2]. The detector, based on the reconstruction of the recoil protons produced in two consecutive (n,p) elastic scattering interactions (DES events), is a matrix of thin scintillating fibers (~250 µm side), arranged in layers orthogonally oriented, for a total size of 16x16x20 cm$^3$.
An innovative silicon SPAD based sensor with integrated electronics has been designed for the detector readout (SBAM sensor [3]) in collaboration with Fondazione Bruno Kessler. The MONDO performance has been evaluated by means of a Monte Carlo simulation developed in FLUKA: a detection efficiency of 10$^{-2}$ -10$^{-3}$ is expected for single and double elastic scattering respectively. The achievable relative energy resolution for the reconstructed neutrons is ~8% and the expected back-pointing resolution is < 1 cm (for a neutron source placed at 20 cm from the detector).
The MONDO detector, its expected performance and the readout calibration results with a matrix prototype will be presented.

[1] W. Newhauser and M. Durante, “Assessing the risk of second malignancies after modern radiotherapy” Nat. Rev. Cancer. 11 (2011) 438

[2] M. Marafini et al., “MONDO: a neutron tracker for Particle Therapy secondary emission characterization” Phys. Med. Biol. 62 (2017)

[3] R. Mirabelli et al., “The MONDO detector prototype development and test: steps towards a SPAD-CMOS based integrated readout (SBAM sensor)” Trans. on Nucl. Science 65 (2018)

Authors

Riccardo Mirabelli (INFN) Giuseppe Battistoni (Università degli Studi e INFN Milano (IT)) Mrs Micol De Simoni (Università di Roma "La Sapienza", Fisica, Rome, Italy) Yunsheng Dong (INFN - National Institute for Nuclear Physics) Marta Fischetti (INFN - National Institute for Nuclear Physics) Dr Leonardo Gasparini (Fondazione Bruno Kessler) Eliana Gioscio ILARIA MATTEI (INFN - National Institute for Nuclear Physics) Mr Enrico Manuzzato (Fondazione Bruno Kessler) Mr Luca Parmesan (Fondazione Bruno Kessler) Vincenzo Patera (University of Rome Sapienza) Dr Matteo Perenzoni (Fondazione Bruno Kessler) Alessio Sarti (INFN e Laboratori Nazionali di Frascati (IT)) Angelo Schiavi (Università di Roma "La Sapienza") Adalberto Sciubba (Sapienza Universita e INFN, Roma I (IT)) Marco Toppi (INFN e Laboratori Nazionali di Frascati (IT)) Giacomo Traini Serena Marta Valle (University of Milan & INFN Sezione di Milano) Yu Zou (Fondazione Bruno Kessler) Michela Marafini (INFN Roma1 - Centro Fermi)

Presentation materials