IWORID 2025

Session

Medical Applications

9 Jul 2025, 09:00

Bratislava, Slovakia

Conveners

Medical Applications: Session 8

• Renata Longo (UNIVERSITY OF TRIESTE & INFN)

Medical Applications: Session 9

• Joaquim Marques Ferreira Dos Santos (Universidade de Coimbra (PT))

226. Timepix detectors for development of novel imaging techniques for ion beam radiotherapy

Maria Martisikova (German Cancer Research Center)

09/07/2025, 09:00

invited talk

Ion radiotherapy is used to treat tumors located close to critical structures such as the brainstem, spinal cord, or optic nerves. In these cases, it is crucial to deliver an adequate dose to the tumour to halt its progression, while minimizing exposure to adjacent healthy tissues. Even minor variations in dose distribution—on the order of several millime-ters—can have significant clinical...

193. Recent developments of helium-beam radiography (αRAD) aiming at image guidance in ion-beam therapy

Tim Gehrke (Heidelberg University Hospital, Radiation Oncology, Heidelberg, Germany)

09/07/2025, 09:30

talk

Ion-beam therapy can offer advantages over the standard radiotherapy with photons, especially for cancer treatments where organs at risk are in close proximity to the tumor to be treated. These advantages mainly result from the characteristic of delivering highly focused doses to the tumor. However, this potential can sometimes not be fully used in clinics, since the focused dose distribution...

130. Carbon-ion radiotherapy monitoring by tracking of charged nuclear fragments: recent clinical results

Rebekka Kirchgässner (Department of Medical Physics in Radiation Oncology , German Cancer Research Centre DKFZ, Heidelberg, Germany)

09/07/2025, 09:50

talk

Carbon-ion radiotherapy provides superior precision in targeting tumors, while significantly reducing the exposure of surrounding healthy tissue to radiation dose as compared to conventional X-ray radiotherapy. However, the same underlying principle increases the sensitivity of the dose distribution to variations of patient positioning and anatomical changes such as nasal cavity filling or...

163. Carbon-ion radiotherapy monitoring with secondary ions: exploiting multi-angle projections for 3D reconstruction of inter-fractional changes

Mr Patrice Schlegel (Department of Medical Physics in Radiation Oncology , German Cancer Research Centre DKFZ, Heidelberg, Germany)

09/07/2025, 10:10

talk

Introduction

Carbon-ion radiotherapy (CIRT) enables highly precise dose delivery through its highly localized dose deposition and enhanced biological effectiveness. However, current treatment guidelines generally do not include daily control imaging throughout the course of a multi-day therapy. As a result, anatomical changes that may occur between fractions cannot be considered due to the...

112. SiC Minipix Timepix3 Detectors for Radiation Research in Particle Therapy

Cristina Oancea

09/07/2025, 11:00

talk

Silicon carbide (SiC) detectors have become essential in advancing dosimetry for high-energy and high-dose rate radiotherapy. Achieving accurate dose tracking under high-dose-rate requires dosimeters that can withstand challenging environments and provide reliable measurements. Conventional silicon detectors, although sensitive, often experience degradation under such conditions due to...

181. Imaging and tracking of clinical proton beam delivery with miniaturized stack telescope Timepix3: Feasibility study of Quality Assurance for Medical Proton Therapy

Samuel Kurucz (Proton Therapy Center)

09/07/2025, 11:20

talk

In current particle radiotherapy practice, it is necessary to evaluate and monitor the beam delivery for the purposes of quality assurance [1]. The current approach at PTC utilizes a scintillator detector (IBA Lynx PT) for determining the accuracy of beam delivery. This detector, while being heavy and large, requires individual dedicated measurements. Additionally, it has a restricted surface...

84. Spatial resolution characteristics of a clinical Photon-Counting Computed Tomography scanner

Francesca Saveria Maddaloni (Università degli Studi di Milano, Dip. di Fisica 'Aldo Pontremoli, Milan (Italy))

09/07/2025, 11:40

talk

Introduction
Computed Tomography (CT) is an integral part of contemporary medicine. Conventional CT scanners are equipped with Energy Integrating Detectors (EID), which are based on indirect conversion of the incoming photons into electric signal for the image generation. EID-based CT shows limitations regarding tissue contrast and spatial resolution. A turning point of the actual CT...

39. Innovative Light Detection System for Rapid 3D Radiation Dose Monitoring

Bartosz Mindur (AGH University of Krakow (PL))

09/07/2025, 12:00

talk

Innovative Light Detection System for Rapid 3D Radiation Dose Monitoring

B. Mindur on behalf of Dose3D Future, AGH University of Krakow, Poland

Introduction

According to the World Health Organization (WHO), cancer remains one of the leading causes of death worldwide. Radiotherapy is often the primary or sole therapeutic approach used in treatment. Ensuring that each patient...

72. Validation of a µCT system simulation with a small-pixel photon-counting spectral detector

Andrew Coathup (INFN Trieste, University of Trieste)

09/07/2025, 12:20

talk

Photon-counting spectral detectors (PCD) have significantly advanced CT imaging by reducing image noise, enhancing contrast and spatial resolution, and enabling spectral imaging [1]. These benefits have extended to µCT imaging, where small-pixel (<100 µm) PCDs have allowed material-specific quantitative imaging at high spatial resolution [2]. Similarly, phase-contrast x-ray imaging (XPCI) has...