The focus of the School is on the most advanced technologies in the fields of semiconductors, very deep submicron and 3D technologies, nanotechnology, advanced packaging and interconnects, telecommunications, real-time signal processing, filtering and massively parallel computing and on the Physics motivations that require confronting these technogical challenges for building the needed new instruments. These Physics motivations are reviewed both in dedicated lectures as well as in all the more technology-based lectures. The school will provide lectures and Lab work in a variety of cross-disciplinary example applications drawn from the exploration of distant Universe, through Medical imaging of the human body, to exploration of the elementary particle world. Lectures on technical developments and science overviews will be given by experts from Academia and Industry, alongside with hands-on Lab sessions with demonstrators and subject specific master-classes on science & technology. Two Public Lectures are scheduled that will take place in different locations in Paris. The morning sessions from 9 am to 1pm will be dedicated to the lectures held in the BioPark main auditorium The afternoon sessions will be devoted to the Lab sessions from 2 to 5pm held in the Physics Department, Building Condorcet. From 5 to 6.30 pm there will be science overview lectures (BioPark Auditorium). All the days (except Sunday July 20) will follow this basic schedule (see present timetable). The school will be held from July 15 to Friday 25 (end of the afternoon), with a break on Sunday where people will enjoy a day free in Paris or surroundings as they like. The program of the Computing and Practical Labs can be find in a booklett format here attached as paper.pdf file. The paper.pdf file includes the tittle of the Labs, the authors'names and an abstract describing them.