Since June 2006 the PAMELA satellite-borne experiment has presented fundamental results on various aspects of cosmic-ray physics. Above all, PAMELA investigated the features present in the antiparticle component of galactic cosmic rays, which have been interpreted in terms of DM annihilation or pulsar contribution. The combination of a permanent magnet with a silicon-strip spectrometer and a imaging calorimeter allows also precision measurements of the entire charged cosmic radiation. In the last ten years PAMELA studied light nuclei and their isotopes, the propagation of particles inside the eliosphere, the short/long variations of the cosmic ray flux due to the Sun’s activity (solar flares, Forbush decrease, solar modulation…), the interactions between galactic particles with the Earth’s magnetosphere and so on. This talk illustrates the most recent scientific results obtained by the PAMELA experiment.