Dear Colleagues, The 5th RD51 Collaboration meeting will take place in Freiburg, Germany from May 24th to May 27th, 2010. The program will consist of plenary sessions and parallel working group (WG) meetings on techniques, detector physics issues, simulations, applications, electronics, and common production and test facilities. The opening plenary session will take place on Monday, May 24th in the afternoon. Based on your feedback and experience from the previous meetings there will be only two WG parallel sessions scheduled at the same time on Tuesday and on Wednesday. On Thursday morning, May 27th there will be closing plenary sessions with the reports from the working group conveners, short presentations of industrial companies and Collaboration Board news. If you are planning to attend the meeting and present your work please contact the corresponding working group convener and register. We are looking forward to see you in Freiburg ! Best regards, Ulrich, Leszek and Maxim.