Workshop+panel discussion targeting NGI managers, related projects, Mediterranean and African partners eInfrastructures, and especially the Grid approach can be regarded (see for example the recommendations from the 2005 OECD Global Science Forum) as a strong catalyst for scientific and technological development in emerging countries. As a matter of fact, granting access to large resources with comparatively small investments in infrastructure is possible and Grids may effectively contribute to bridge digital divide and fight the drain brain in developing countries. Initiatives in line with this vision have been already established in several world regions. The workshop aims at discussing status and future strategies with special reference to Africa and the Middle East, including the extension of this approach to Sub-Saharan Africa. Open issues and specific problems of the region will be analyzed as well.