Dr
Ignacio Blanquer
(UPV)
12/02/2008, 11:00
Application Porting and Deployment
Oral
Metagenomic analysis requires several iterations of alignment and phylogenic classification steps. Source samples reach several millions of sequences. These sequences are compared to the eukaryotic species of the "Non-redundant" database.
The deployment process involves three stages: First, public databases are copied in relevant SEs to reduce the access time by increase the geographic...
Dr
Christophe Blanchet
(CNRS IBCP)
12/02/2008, 11:20
Scientific Results Obtained Using Grid Technology
Oral
The nucleosome involves a complex of eight proteins (histones) binding to 147 base-pairs of DNA. Simulating a nucleosome core bound to a single DNA sequence would require treatment of roughly 250,000 atoms and many months of computer time. To understand selective binding we need to compare many potential binding sequences and hence perform many such simulations. Given that any of the four...
Mr
Alexandru Ionut Munteanu
(INSERM, UMR S 525, Faculté de Médicine Pitié-Salpêtrière, Paris, France)
12/02/2008, 11:40
Application Porting and Deployment
Oral
As part of the research conducted at the INSERM U525 laboratory, the THESIAS software was created in order to analyze statistically, associations between gene polymorphisms and diseases. Given a data set containing the genotypes of case and control individuals, THESIAS measures haplotype frequencies combining several polymorphisms and associations with the disease. Until now this kind of...
Dr
Andreas Gisel
(Istituto di Tecnologie Biomediche, CNR)
12/02/2008, 12:00
Scientific Results Obtained Using Grid Technology
Oral
To find correlation between genes within different experiments, clustering is a good and challenging analysis method for data sets of such size and complexity. We have chosen an unsupervised hierarchical clustering algorithm based on the cooperative behaviour of an inhomogeneous lattice of coupled chaotic maps, the Chaotic Map Clustering.
Analyzing data sets of 587 samples we were able to...