21-25 September 2009
Hotel Barcelo Sants
Europe/Zurich timezone

Grid enabling framework for population SNPs genetic linkage analysis.

Not scheduled
Hotel Barcelo Sants

Hotel Barcelo Sants

Barcelona
Poster

Speaker

Dr Luciano Milanesi (National Research Council - Institute of Biomedical Technologies)

Project(s) or EGEE activity presenting the demo or poster (project or activity names only)

EGEE-III NA4

Abstract

The genetic linkage analysis of Single Nucleotide Polymorphism (SNP) markers has recently become a very popular approach for genetic epidemiology and population studies, aiming to discover the genetic correlation in complex diseases. The high computational cost and memory requirements of the major algorithms proposed in literature make analyses of medium/large data sets very hard on a single CPU. The genotyping technologies have greatly facilitated the study of DNA variations in large size samples, allowing the association of the genetic patterns to different clinical phenotypes. We present a performance analysis of a distributed approach for large genetic SNP and mutation studies on high throughput genotyping data based on EGEE Grid platform.

Special requirements other than the set up mentioned in the CfA text.

none

Primary author

Dr Luciano Milanesi (National Research Council - Institute of Biomedical Technologies)

Co-authors

Dr Alessandro Orro (National Research Council - Institute of Biomedical Technologies) Dr Andrea Calabria (National Research Council - Institute of Biomedical Technologies) Dr Davide Di Pasquale (National Research Council - Institute of Biomedical Technologies) Dr Gabriele Trombetti (National Research Council - Institute of Biomedical Technologies) Dr Matteo Gnocchi (National Research Council - Institute of Biomedical Technologies)

Presentation Materials