Description
The present demonstration shows the integration of existing data sources towards a global surveillance network for molecular epidemiology, based on Service Oriented Architecture and Grid technologies. Its relevance is being tested through the current H1N1 outbreak. The idea is to dynamically analyze the molecular biology data, made available on public databases (such as IVR, IVDB, or EpiFlu), using computing, storage and automatic updating services offered by Grid. Bioinformatics methods of sequence alignment will highlight mutations on virus genome. Phylogenetic analyzes will characterize evolutionary history, key point to understand the geographic and molecular source of this outbreak where the virus seems to be a reassortant from avian and human forms. Dynamical database management and deployment of phylogenic workflow on EGEE and EUAsiaGrid resources will be presented using the interoperable WISDOM production environment. The goal is to be ready to impact the next pandemics.
