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This work presents the recent developments of the FLUKA [1,2,3] Particle Therapy Tool [4]. FLUKA is a general-purpose Monte Carlo (MC), particle transport code, used for an extended range of applications including medical physics. Together with the support of its graphical user interface Flair [5,6], an easy-to use platform was developed for MC simulations in particle therapy. It has already...
Characterization of commercial photo-devices as dose-rate sensors
M.A. Carvajal1, I. Ruiz-García1, J. Román-Raya2, J. Montes2, D. Guirado2, P. Escobedo1, A. Martínez-Olmos1, A.M. Lallena Rojo1 , A.J. Palma1
1 University of Granada, Granada, Spain
2 Universitary Hospital San Cecilio, Granada, Spain
Introduction. The main application of photodiodes, phototransistors is to measure...
Design study of a lightweight superconducting gantry applied to proton therapy was performed at HUST. By using alternating-gradient (AG) CCT magnets, the footprint and weight of the gantry can be significant reduced. Meanwhile, a large momentum acceptance avoids the requirement of fast magnetic field change of superconducting magnets during tumor treatment. We presented a beam optics design...
Recently, the superconducting gantry is gained more and more attentions due to the advantages on the reduction of the footprint and weight. Aiming at the light weight gantry beamline with a large momentum acceptance, we proposed a superconducting gantry scheme employing a fast degrader, combined-function AG-CCT magnets and downstream scanning nozzle. To reduce the secondary neutrons on the...
SC230 a 230 MeV superconducting cyclotron designed in JINR. It is intended to be developed as a joint project with ASIPP. The cyclotron is designed for proton therapy and biomedical research. This presentation focuses on the results of the conceptual design of the accelerator. In the process of physical design, simulations of the magnetic and RF systems were carried out, the main...
The Physikalisch-Technische Bundesanstalt (PTB), Germany's national primary standard laboratory, operates a custom-designed electron LINAC for the generation of high energy electron and photon radiation for research in the field of dosimetry for radiation therapy. The beam energy of this LINAC is variable in the range from 0.5 MeV up to 50 MeV.
The preparation of a beam at a LINAC is an...
Purpose: Since December 2016 at the MedAustron Ion Therapy center (MA) patients have been treated with protons. The synchrotron accelerator is also able to deliver carbon ions with energies between 120 and 402.8 MeV/u (ranges from 2.9 to 27 cm in water). In this work we report the results of dosimetric commissioning of the pencil beam algorithm PBv3.0 available in the treatment planning...
ABSTRACT
In radiotherapy, treating of cancer patients require the use of immobilizing devices such as thermoplastic masks. These masks increase the patient skin doses, but its effect is normally overlooked. This work is done to determine the thermoplastic mask factor to compensate for it just as applied to trays and wedges. Measurements are done at source-to-suface distance of 80 cm for...
Charged Particle Therapy (CPT) is a highly effective method for treating several types of solid tumours. However, in heavy ion therapy nuclear inelastic interactions of the incident beam with the patient tissues lead to the break-up of the incident ion. The produced fragments of projectile have a longer range with respect to the primaries and lead to an undesirable dose deposition beyond the...
Introduction: Cyclotron-based proton therapy facilities use an energy degrader of variable thickness to deliver the beam of the energy required by treatment plan. Together with the energy reduction, the transverse size and energy spread increase. The collimation and energy selection systems downstream of the degrader cut the beam to match the following beamline, that introduces...
The transparent polymer polyallyl-diglycol-carbonate (PADC), also known as CR-39, is widely used for ion detection in laser-plasma interactions. It allows for detection of single protons and ions via formation of microscopic tracks after etching in NaOH or KOH solutions. PADC combines a high sensitivity and high specificity with inertness towards electromagnetic noise.
We have developed...
PENH was initially developed as the extension of PENENELOPE (a code system for Monte Carlo simulation of electron and photon transport), which incorporated the electromagnetic transport of protons aiming to its application to protontherapy. Nevertheless, the absence of nuclear interactions prevented the accurate estimation of the dose deposition along the beam axis in protontherapy...
In particle therapy, an on-line treatment verification device is highly required to reduce the uncertainty of the actual particle range during the patient irradiation and interfractional morphological changes. The final aim is to improve the robustness and effectiveness of the treatment in terms of conformity of the dose released to the target.
The INSIDE bi-modal system is currently in the...
In proton therapy, in-vivo PET range verification requires a comparison of the measured and expected β$^{+}$ activity distribution produced by the proton beam by means of nuclear reactions on the most abundant elements in the body of the patient: C, O, N and, to a lesser extent, P and Ca. The accuracy of the expected activity distributions depends on the accuracy of the Monte Carlo...
FLASH radiotherapy is a novel treatment modality, which promises reduced normal tissue toxicity while keeping the same tumor control. This so-called "FLASH effect" can be observed when delivering high doses of radiation in very short time and was demonstrated by Favaudon et al. in 2014 using a 4.5 MeV electron beam to irradiate mouse lungs in vivo. Since then multiple other experiments...
Proton therapy for cancer treatment is a rapidly growing field as increasing evidence suggests it induces more complex damage in DNA than photons [1]. Accurate comparison between the two requires quantification of the damage caused, one method being the comet assay [2]. The program discussed here, based on neural network architecture, aims to speed up analysis of comet assay images and provide...
The secondary neutrons produced in Particle Therapy treatments can travel along the path inside the patient and contribute with additional dose in-and out-of-field. This unwanted dose increases the risk of developing secondary cancers: late insurgences are particularly crucial in paediatric patients where the closeness of the organs and the recurrence onset strongly impacts the life...
To fully exploit the advantages of therapeutic ion beams, on-line monitoring of the dose deposition would be highly desirable. At present, several methods have been proposed to determine the beam range using the secondary radiation originating from the interactions between the therapeutic beam and the tissues. Two main techniques are prompt gamma imaging (PGI) and positron emission tomography...
