Speaker
Prof.
Irena Malinowska
(Faculty of Chemistry, M. Curie-Skłodowska Univ.)
Description
In the last years development of technology based of superconducting is observed. In consequence a lot of devices created a strong magnetic field is constructed. The devices can be used in different fields of live: in industry, in medicine etc. In consequence a lot of living organism are exposed on influence of strong magnetic field - in intended or intended.
A lot of processes in nature carried out in interfacial boundary. The interfacial phenomena influenced on a lot of process in nature including living organism too. So the investigations how magnetic field influenced interfacial phenomena is very important. As an experimental method liquid chromatography in magnetic field (so called magnetochromatographya0 was used, as a chromatographic technique -thin-layer chromatography in magnetic field. Chromatography is an analytical method based on the interfacial interactions of separation solutes. Comparison retention data obtained in magnetic field and outside it can give us some information about influence of magnetic field on the interfacial phenomena. In living organism a very important phenomenon is transport of solutes through biological membranes. There are liquid chromatography systems (RP, MLC) imitated biological membranes. Comparison suitable retention parameters which are used as descriptors of biological activity can give us information about influence of magnetic field on transport of biological and pharmacological activity substances through biological membranes.
In case of the reversed phase experiment, the influence of the magnetic field on log kw – one of the crucial QSAR parameters - was investigated. Because log kW values of investigated compounds obtained in magnetic field and outside are different, it may suggest, that presence of external magnetic field may also amplify or otherwise modify biological activity of examined compounds
Primary author
Prof.
Irena Malinowska
(Faculty of Chemistry, M. Curie-Skłodowska Univ.)
Co-authors
Dr
Henryk Malinowski
(Vexler and Baldin Laboratory of High Energy Physics, Joint Institute for Nuclear Research, Dubna,)
Dr
Marek Studziński
(Faculty of Chemistry, M. Curie-Sklodowska Univ.)
