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24–28 Jun 2018
Sundsvall
Europe/Zurich timezone

Low dose single shot two-dimensional phase contrast imaging

27 Jun 2018, 09:00
20m
Quality Hotel, Folkets Hus (Sundsvall)

Quality Hotel, Folkets Hus

Sundsvall

Esplanaden 29 Sundsvall, Sweden
Oral general Oral

Speaker

Mr Erik Schou Dreier (Niels Bohr Institute, University of Copenhagen)

Description

X-ray phase contrast imaging provides a method to distinguish materials with similar density and effective atomic number, which otherwise would be difficult using conventional X-ray absorption [1]. In the recent decade, multiple methods have been developed to acquire X-ray phase contrast images using incoherent laboratory sources. One of these is the Double Masked Edge Illumination (DM-EI) method. DM-EI enables a large field of view and makes it possible to utilize the full energy range of conventional X-ray laboratory sources [2]. However, the method needs a minimum of two image acquisitions to do a full phase retrieval, and it requires relatively complicated mask apertures or even additional sample exposures to make a two-dimensional phase contrast image.

We have developed, and experimentally tested, a low dose, single mask, edge illumination method that enables two-dimensional phase contrast images in a single shot (Figure 1). The method is based on the technique originally proposed by F. Krejci et al. [3], and uses a micro focus source, a two-dimensional mask, and an Advapix detector, which contains the Timepix3 chip developed by the Medipix consortium. By using a highly absorbing, pre sample tungsten mask, our single shot method is capable of producing phase contrast images at low sample radiation dose and is applicable for both hard and soft X-rays. In addition to this, the method shows great potential for further development by using the Timepix3’s fast time of arrival information.

Primary author

Mr Erik Schou Dreier (Niels Bohr Institute, University of Copenhagen)

Co-authors

Mrs Chantal Silvestre (Department of Micro- and Nanotechnology, DTU Nanotech,Technical University of Denmark, ) Dr Jan Kehres (Department of Physics, DTU Physics, Technical University of Denmark) Dr Jan Jakubek (ADVACAM s.r.o.) Ms Mohamad Khalil (Department of Physics, DTU Physics, Technical University of Denmark) Dr Robert Feidenhans'l (European XFEL GmbH) Dr Ulrik Lund Olsen (Department of Physics, DTU Physics, Technical University of Denmark)

Presentation materials