28–31 Aug 2018
EPFL
Europe/Zurich timezone

【934】 Microfabricated nanomotion detectors for ultra-rapid bacterial sensitivity tests

29 Aug 2018, 18:30
1h 30m
Salle polyvalente (EPFL)

Salle polyvalente

EPFL

Poster Biophysics, Medical Physics and Soft Matter Poster Session

Speaker

Mr Anton Malovichko

Description

With the misuse of antibiotics and the increasing number of multi-resistant
living organisms, antimicrobial resistance becomes a very serious public
health issue. Conventional techniques for antibiotic sensitivity
characterization requires 24 h to one month.
Our group developed a cantilever based nanomotion detector that provides the same result in less than one hour. The organism of interest is attached onto a cantilever and its nanoscale movements induce cantilever oscillations. If the organism is exposed to an antibiotic to which it is sensitive and that compromises its viability, the
oscillations stop.
This work proposes microfabricated device with an array of such nanomotion detectors. Miniaturization of the chip and integration with a microfluidic system will permit to monitor dozens of microorganisms simulatenously.

Authors

Mr Anton Malovichko Dr Sandor Kasas Dr Kamila Guérin Prof. Giovanni Dietler

Presentation materials

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