28–31 Aug 2018
EPFL
Europe/Zurich timezone

【935】 Ultrasensitive NMR and MRI with hyperpolarised radionuclei

29 Aug 2018, 18:30
1h 30m
Salle polyvalente (EPFL)

Salle polyvalente

EPFL

Poster Biophysics, Medical Physics and Soft Matter Poster Session

Speaker

Jared Croese (Universite de Geneve (CH))

Description

MRI is a versatile and widely used imaging technique, which is based on the principles of NMR. However, both techniques suffer from an inherent insensitivity due to very small levels of polarization. By combining hyperpolarization techniques with detection of the NMR signal through the asymmetry of radioactive beta or gamma decay an increase in NMR sensitivity by almost 10 orders of magnitude is achievable. This increase in sensitivity will drastically decrease NMR and MRI measurement times. First studies on 26Na in liquid samples were performed, with the aim to study Na interaction with biological samples. In addition MRI experiments using radioactive Xe isotopes (131m, 133m) are planned. These can be used in lung and brain imagining.

Authors

Abhilash Javaji (Universitaet Oldenburg (DE)) Dalibor Zakoucky (Acad. of Sciences of the Czech Rep. (CZ)) F Hofmann (University of Copenhagen) Frank Wienholtz (CERN) Fredrik Olof Andre Parnefjord Gustafsson (KU Leuven (BE)) Gerda Neyens (CERN) Hanne Heylen (CERN) J Wolak (Adam Mickiewicz University, Poznan, Poland) Prof. Janez Plavec (National Institute of Chemistry, Ljubljana, Slovenia) Jared Croese (Universite de Geneve (CH)) Prof. Jean-Noel Hyacinte (Haute Ecole Spécialisée de Suisse occidentale) Karolina Kulesz (Warsaw University of Technology (PL)) Dr Kosma Szutkowski (Adam Mickiewicz University, Poznan, Poland ) Lars Hemmingsen (University of Copenhagen (DK)) Mr Luca Cerato (Universite de Geneve (CH)) Prof. Maciej Kozak (Adam Mickiewicz University,Poznań, Poland) Magdalena Kowalska (CERN) Mr Marcus Jankowski (Universitaet Oldenburg (DE)) Mark Bissell (University of Manchester (GB)) Michal Walczak (Politechnika Poznan Uni Technology Faculty of Technical Physic) Miguel Madurga Flores (University of Tennessee (US)) Mikolaj Hubert Baranowski (University Adam Mickiewicz (PL)) Philipp Wagenknecht (Universitaet Oldenburg (DE)) Prof. Renaud Blaise Jolivet (CERN and University of Geneva) Robert Dale Harding (University of York (GB)) Robin Yoel Engel (Universitaet Oldenburg (DE)) Stavroula Pallada (CERN) Tassos Kanellakopoulos (KU Leuven (BE)) Thierry Stora (CERN) Victoria Isabel Araujo Escalona (KU Leuven (BE)) Dr Vojč Kocman (National Institute of Chemistry, Ljubljana, Slovenia) Prof. Walter Neu (Universitaet Oldenburg (DE)) Mr Wouter Anton M Gins (KU Leuven (BE)) X.F. Yang (Peking University of Technology)

Presentation materials

There are no materials yet.