25–29 Jun 2023
Ole-Johan Dahls Hus
Europe/Oslo timezone

Design and characterisation of a treatment monitoring system for carbon-ion radiotherapy based on 28 Timepix3 detectors

27 Jun 2023, 11:40
20m
Simula Auditorium (Ole-Johan Dahls Hus)

Simula Auditorium

Ole-Johan Dahls Hus

Oslo Science Park Gaustadalléen 23B, 0373 Oslo
Oral Detector systems Detector Systems

Speaker

Dr Laurent Kelleter (German Cancer Research Centre DKFZ)

Description

Compared with conventional X-ray radiation therapy, carbon-ion beam radiotherapy reduces the dose to the healthy tissue around a tumor thanks to the escalating dose at the Bragg peak. We developed a tracking system for secondary radiation from carbon-ion beams based on seven modules of four Timepix3 detectors (“quad module”). The tracking system measures the secondary radiation of different treatment fractions delivered on consecutive days, and thus detects undesired treatment variations. In this contribution, the design and characterisation of the tracking system will be presented. The characterisation focused on the detection, localisation and identification of internal density changes in human head models. A clinical study focusing on monitoring the treatment of tumors of the head and neck region has been started.

Primary author

Dr Laurent Kelleter (German Cancer Research Centre DKFZ)

Co-authors

Mr Gernot Echner (German Cancer Research Centre DKFZ) Dr Jan Jakubek (ADVACAM s.r.o.) Prof. Juergen Debus (Heidelberg University Hospital) Mrs Luisa Schweins (German Cancer Research Centre DKFZ) Mr Lukas Marek (ADVACAM s.r.o.) Dr Malte Ellerbrock (Heidelberg Ion Beam Therapy Center) Dr Marcus Winter (Heidelberg Ion Beam Therapy Center HIT) Dr Maria Martisikova (German Cancer Research Centre DKFZ) Mr Martin Jakubek (ADAVCAM s.r.o.) Prof. Oliver Jaekel (German Cancer Research Centre DKFZ) Mrs Pamela Ochoa Parra (German Cancer Research Centre DKFZ) Mrs Rebekka Kirchgaessner (German Cancer Research Centre DKFZ) Dr Renato Felix Bautista (German Cancer Research Centre DKFZ) Dr Semi Harrabi (Heidelberg Ion Beam Therapy Center HIT) Mr Stefan Schmidt (German Cancerr Research Center) Dr Tim Gehrke (German Cancer Research Centre DKFZ)

Presentation materials

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