1st MEDICIS-Promed ESRs General Training, Manchester

6 Sept 2016, 09:00 → 9 Sept 2016, 17:00 Europe/London

3rd floor seminar room (National Graphene Institute)

This event is the first General Training of the MEDICIS-Promed network. It will be dedicated to two topics:

• Fundamentals of nuclear physics
• Advanced materials

The training will be completed with transferrable skills and presentations on each work package by the ESRs.

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MEDICIS-Promed is a Horizon2020 Marie Skłodowska-Curie Innovative Training Network dedicated to the production and research around novel medical radioisotopes.

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Event Organising Committee

• Sabina Hawthornthwaite, University of Manchester
• Charlotte Hooson-Sykes, University of Manchester
• Thomas Cocolios, KU Leuven
• Fiona Reid, University College London Consultants
• Cristina Ferrari, CERN

Manchester-CampusMap.pdf

Tuesday 6 September

09:00 → 09:30 Welcome

09:00 Welcome from the local host

Speaker: Mrs Sabina Hawthornthwaite (The University of Manchester)

09:15 Welcome from the Training Office

Speaker: Prof. Thomas Elias Cocolios (KU Leuven - IKS)

TrainingOfficeNews.pdf

09:30 → 10:30 Work package overview: 1: Isotope mass separation

The ESRs will present their work package to each other with 1 overview presentation and a series of fast-paced presentations.

NanoScale_Sanjib presentation.pdf

Presentation_Maddalena.pdf

Presentation_Nhât-Tân.pdf

Presentation_Vadim.pdf

09:30 Package overview

Overview of the work package

Speaker: Nhat-Tan Vuong (CERN)

Presentation_Nhât-Tân.pdf

Presentation_Nhât-Tân.pptx

09:50 3-min talk

3-minute talk by an ESR

Speaker: Mr Sanjib Chowdhury (IST, C2TN)

NanoScale_Sanjib presentation.pdf

09:55 3-min talk

3-minute talk by an ESR

Speaker: Mrs Marina Nazarova (The University of Manchester)

10:00 3-min talk

3-minute talk by an ESR

Speaker: Mr Vadim Gadelshin (Johannes Gutenberg University of Mainz)

10:05 3-min talk

3-minute talk by an ESR

Speaker: Maddalena Maietta (Centre National de la Recherche Scientifique (FR))

Presentation_Maddalena.pdf

10:30 → 10:45 Coffee break

10:45 → 12:00 Transferrable skills: Investment

Development into transferrable skills that had been identified as most interesting following the MEDICIS-PROMED kick-off meeting in February 2016:
INVESTMENT: how finance interacts with innovation
INSTITUTIONS: some policy, regulatory and organisational environments around innovation
INNOVATION: integration, partners and creating value

Convener: Ms Fiona Reid

10:45 Transferrable skills:Investement

Speaker: Ms Fiona Reid

12:00 → 13:00 Lunch

13:00 → 14:50 Advanced Materials: Part I

The new, exciting field of 2D materials has seen exponential growth since the isolation of graphene, a single atomic layer of carbon atoms, at The University of Manchester in 2004. In this session on Advanced Materials the team of Nobel Prize winner Prof Sir Kostya Novoselov, based at The National Graphene Institute in Manchester, will provide an introduction to advanced materials such as graphene, tungsten disulphide and a range of other 2D materials. ESRs will gain an understanding of the world of 2D atomic materials, including their properties and characteristics, how 2D materials are produced, and their potential applications. The session will cover:
1) Electronic and optical properties of graphene
2) Mechanical properties of graphene
3) Permeation properties of graphene membranes
4) Methods to grow graphene
5) Materials beyond graphene
6) Van der Waals heterostructures: physics and applications

Convener: Prof. Konstantin Novoselov

Presentation_Marina.pdf

14:50 → 15:10 Tea Break

15:10 → 17:00 Advanced Materials: Part II

The new, exciting field of 2D materials has seen exponential growth since the isolation of graphene, a single atomic layer of carbon atoms, at The University of Manchester in 2004. In this session on Advanced Materials the team of Nobel Prize winner Prof Sir Kostya Novoselov, based at The National Graphene Institute in Manchester, will provide an introduction to advanced materials such as graphene, tungsten disulphide and a range of other 2D materials. ESRs will gain an understanding of the world of 2D atomic materials, including their properties and characteristics, how 2D materials are produced, and their potential applications.

Convener: Prof. Konstantin Novoselov

Zheling Li (Bennie)-Graphene Composites-06092016.pdf

Wednesday 7 September

09:00 → 10:00 Work package overview: 2- PET-aided hadron therapy

The ESRs will present their work package to each other with 1 overview presentation and a series of fast-paced presentations.

Presentation_Fam.pdf

Presentation_Johanna.pdf

Presentation. KyungDoi.pdf

Presentation_Simon.pdf

09:00 Package overview

Overview of the work package

Speaker: Johanna Pitters (CERN)

Presentation_Johanna.pdf

09:20 3-min talk

3-minute talk on an ESR topic

Speaker: Mr Tkhe Kyong FAM (EPFL)

Presentation_Fam.pdf

09:25 3-min talk

3-minute talk on an ESR topic

Speaker: Kyung Don Choi

KyungDoi presentation.pdf

09:30 3-min talk

3-minute talk on an ESR topic

Speaker: Simon Thomas Stegemann (KU Leuven)

09:35 3-min talk

3-minute talk on an ESR topic

10:00 → 10:15 Coffee break

10:15 → 12:00 Transferrable skills: Institutions

Development into transferrable skills that had been identified as most interesting following the MEDICIS-PROMED kick-off meeting in February 2016:
INVESTMENT: how finance interacts with innovation
INSTITUTIONS: some policy, regulatory and organisational environments around innovation
INNOVATION: integration, partners and creating value

Convener: Ms Fiona Reid

12:00 → 13:00 Lunch

13:00 → 14:50 Fundamentals of nuclear physics: Lectures Part 1

The basics of radioactivity and the handling of radionuclides will be presented. This lecture and laboratory series is based upon the successful Nuclear Technology Education Consortium, a professional masters programme established in Manchester and lead by Prof. John Billowes.

Conveners: Prof. Jonathan Billowes (university of manchester), Dr Kieran Flanagan (University of Manchester (GB))

14:50 → 15:10 Tea break

15:10 → 17:00 Fundamentals of nuclear physics: Lectures Part 2

The basics of radioactivity and the handling of radionuclides will be presented. This lecture and laboratory series is based upon the successful Nuclear Technology Education Consortium, a professional masters programme established in Manchester and lead by Prof. John Billowes.

Thursday 8 September

09:00 → 10:00 Work package overview: 3- Radiopharmaceuticals for ovarian cancer

The ESRs will present their work package to each other with 1 overview presentation and a series of fast-paced presentations.

Presenation_Alice.pdf

Presentation_Annie.pdf

Presentation_Francesco.pdf

09:00 Work package overview

Overview of the work package

Speaker: Dr Cicone Francesco (CHUV)

09:20 3-min talk

3-minute talk on an ESR topic

Speaker: Mrs Alice D'Onofrio (Instituto Superior Tecnico, C2TN)

09:25 3-min talk

3-minute talk on an ESR topic

Speaker: Roberto Formento Cavaier (Centre National de la Recherche Scientifique (FR))

09:30 3-min talk

3-minute talk on an ESR topic

Speaker: Annie Julia Ringvall-Moberg

Presentation_Annie.pdf

09:35 3-min talk

3-minute talk on an ESR topic

10:00 → 10:15 Coffee break

10:15 → 12:00 Transferrable skills: Innovation

Development into transferrable skills that had been identified as most interesting following the MEDICIS-PROMED kick-off meeting in February 2016:
INVESTMENT: how finance interacts with innovation
INSTITUTIONS: some policy, regulatory and organisational environments around innovation
INNOVATION: integration, partners and creating value

Convener: Ms Fiona Reid

12:00 → 13:00 Lunch

13:00 → 17:00 Fundamentals of nuclear physics: Practical session

The basics of radioactivity and the handling of radionuclides will be presented. This lecture and laboratory series is based upon the successful Nuclear Technology Education Consortium, a professional masters programme established in Manchester and lead by Prof. John Billowes.

Conveners: Prof. Jonathan Billowes (university of manchester), Dr Kieran Flanagan (University of Manchester (GB))

Friday 9 September

09:00 → 10:30 Student presentations

Giving the opportunity to ESR and non-ESR to present their work to each other

09:00 PET scanning of ocular melanoma after proton therapy

The Proton Therapy Facility at TRIUMF is in routine operation treating ocular tumours using 74 MeV protons extracted from the 500 MeV H- cyclotron. Proton therapy results in the activation of the irradiated tissue and provides an opportunity for in-vivo verification via the measurement of irradiation induced activity. The activity distribution resulting from these irradiation induced positron emitters is measurable through post-therapeutic positron emission tomography (PET) scans. The feasibility of using PET as a verification tool for eye treatment is being investigated in this project. A lucite target and a 3-D printed eye were irradiated with a pristine/raw Bragg Peak (RBP) and a Spread-out Bragg peak (SOBP). The isotopic activity inside the targets was calculated with Monte Carlo codes GEANT4 and FLUKA and validated with data from PET scanners taken 15 minutes after end of beam (EOB).

Speaker: Tanjil Amin (University of Huddersfield)

09:20 ISOLTRAP the mass measurement tool of ISOLDE/CERN and its power to enhance the radio isotope production for medical purposes

The ISOLDE facility at CERN provides a wide choice (>1000 different radioisotopes) of mass-separated ion beams. These serve a variety of disciplines, including radiochemistry, radiobiology and preclinical studies for nuclear medicine. Recently the quadruplet of terbium (Tb) isotopes covering all modalities of nuclear medicine gained considerable interest [1]. Neutron-deficient lanthanide isotopes such as 149,152,155Tb are produced at ISOLDE by 1.4 GeV proton induced spallation of tantalum foil targets. The radionuclides diffuse out of the 2000 °C hot target and are surface or laser ionized, accelerated to 30-60 keV and mass separated. Due to the chemical similarity of the lanthanides the separated beam is not mono-isotopic but also contains isobars of the selected mass plus sidebands of oxide ions 16 mass units less. Most of these are radioactive with different half-lifes and a wealth of gamma rays which renders difficult a quick on-line assessment of the beam composition by gamma ray spectrometry.
We present a new tool for this purpose, the so called multi-reflection time-of-flight mass spectrometer (MR-ToF MS) [2] which is used at the high-resolution mass spectrometer ISOLTRAP [3]. With the support of the spectrometer it is possible to analyse the composition of the collected beam immediately and vary the production parameters in order to enhance even more the purity of the isotope of interest.

References:
[1] C. Müller et al., J. Nucl. Med. 53, 1951 (2012).
[2] R.N. Wolf et al. Int. J. Mass Spectrom. 349-350, 123–133 (2013).
[3] S. Kreim et al. Nucl. Instrum. Methods B 317, 492–500 (2013).

Speaker: Andree Welker (Technische Universitaet Dresden (DE))

Welker_ISOLTRAP_1st_promed_training_MEDICIS_2016.pdf

Welker_ISOLTRAP_1st_promed_training_MEDICIS_2016.pptx

09:40 TBA

TBA

Speaker: Yisel Martinez Palenzuela (KU Leuven (BE))

10:30 → 10:45 Coffee break

10:45 → 12:15 Maximising Impact: Expert panel

Panel discussion with Manchester experts in creating impact from fundamental research, featuring Dr Alick Deacon (Technology Translation Fellow) and Dr Emma Nichols (Ogden Science Officer)

Conveners: Dr Alick Deacon, Mr Dee-Ann Johnson, Dr Emma Nichols

12:15 → 12:45 Present and future work on graphene at CERN ISOLDE

This includes ongoing work on the interaction between graphene and adatoms/admolecules, future work on direct doping of graphene by substitution of C atoms with impurities etc.

Speaker: Lino Miguel Da Costa Pereira (KU Leuven (BE))

12:45 → 13:00 Visit NGI

Visit of the facilities at the National Graphene Institute

13:00 → 14:00 Lunch

14:00 → 15:00 Graphene/2D group Seminar

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