I present a viable two leptoquark model based on $SU(5)$ gauge symmetry that addresses the $B$-physics anomalies. The entire low-energy flavor structure of the set-up originates from two $SU(5)$ operators that relate Yukawa couplings of the two leptoquarks. The proposed scenario accommodates all measured lepton flavor universality ratios in $B$-meson decays, is consistent with related flavor observables, and is compatible with direct searches at the LHC. The model is self-consistently perturbative, provides gauge coupling unification, and predicts several yet-to-be-measured flavor observables. I also discuss prospects for future discoveries of the two leptoquarks at the LHC.