Very High Energy Electron Radiotherapy Workshop (VHEE'2020)

Europe/Zurich
CERN

CERN

Angeles Faus-Golfe (Université Paris-Saclay (FR)) , Manjit Dosanjh, Roberto Corsini (CERN)
Description

VHEE2020

Establishing innovative treatment modalities for cancer is a major 21st century health challenge. Although accelerated electrons are widely used to generate X-rays for radiotherapy, electrons are less frequently used directly because low energy electrons have limited penetration range and are  mostly for the treatment of superficial tumours and thus limiting their clinical applicability.

Recently, studies involving ultra-high dose rate (mean dose rate above 100 Gy/s) delivery of ionizing radiation, termed FLASH radiotherapy (FLASH-RT), have uncovered some unexpected but possible therapeutic benefits caused tremendous excitement in the radio-oncology fieldData appear to show that FLASH-RT affords significant normal tissue sparing without compromising tumour control.

In addition, the idea of investigating the use of very high-energy (50-250 MeV) electron (VHEE) beams for RT has gained interest, since electrons with higher energies can travel deeper into the patient. The advantages of this very high-energy electron therapy (VHEE) are that the depth – dose profile from the electrons is flatter than the quasi-exponential dose given by X-rays, and in addition – in principle – the delivered electrons (which are charged) may be focused and steered in ways that are not possible for X-rays. The challenge until recently has been the difficulty in obtaining high-energy electrons using compact machines. This can now be overcome either with high-gradient cavities or by using laser-based acceleration.

Therefore, it is highly timely to have a follow up meeting to VHEE 2017 https://www.cockcroft.ac.uk/events/VHEE17/

The list of topics to be explored are:

  • State of the Art;
  • Mechanism and Innovation for FLASH RT;
  • New indications and hot topics;
  • Facilities  description: current and planned, e.g. exploitation and use of the existing facilities CLEAR, CLARA, ELBE, PITZ;
  • Demonstrate capability of conventional RF acceleration techniques including SC for VHEE RT applications;
  • Overall VHEE compact machine design including costing;
  • Dosimetry and Detectors;
  • Treatment Planning, Modelling and Imaging;
  • Accelerators R&D and Technologies for medical treatment, e.g. novel acceleration techniques;
  • Industrial panel for medical technologies and plans;
  • Where are we going? Which experiments/facilities are needed?

The sessions will be fully remote. The video details will be communicated one week before the meeting. 

For organisational purposes, you are kindly requested to REGISTER to this event using the form on the left menu.

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Participants
  • ABDELKRIM EL HASSINI
  • Abdessamad AMINE
  • Achim Weidemann
  • Adam Harrington
  • Ahmet Ayan
  • Ahmet Serdar MUTLUER
  • Alberto Degiovanni
  • Alejandro Castilla Loeza
  • Alessandro Cianchi
  • Alessandro Gallo
  • Alessia Ciccotelli
  • Alessia Gasparini
  • Alessio Sarti
  • Alessio Sarti
  • Alexander Cahill
  • Alexander Gerbershagen
  • Alexander Jenkins
  • Alexandra Bourgouin
  • Alexey Lyapin
  • Alexia Augier
  • Alireza Ehtesham
  • Amanda Diez Fernandez
  • Amélia Maia Leite
  • Ana Carolina Correia da Silva Padua
  • Anastasiya Magazinik
  • Anders Brahme
  • Andrea Calandra
  • Andrea Latina
  • Andrea Mostacci
  • ANDREAS SCHÖNFELD
  • Andreas Schüller
  • Andrew Minchinton
  • Andrew Poynter
  • Andrew Rosenstrom
  • andrew wibawa
  • Anna Giribono
  • Anna Grebinyk
  • Anna Subiel
  • Anna Vnuchenko
  • Annalisa Patriarca
  • Anne Oppelt
  • Annika Gabriel
  • Anouk Sesink
  • Anthony Bonfrate
  • Antonio Gilardi
  • Anusorn Lueangaramwong
  • Arnaud Pin
  • Arnd Ernst Specka
  • Arthur BONGRAND
  • Arun Ganguly
  • Ashley Ong
  • Audrey Bouchet
  • AUDREY-ANNE OEI
  • Aymeric Almeida
  • Benito Gimeno Martínez
  • Benjamin Frisch
  • Benjamin Graffel
  • Benjamin Hornberger
  • Benjamin Williams
  • Benoit Petit
  • Berardino De Bari
  • Bill Loo
  • Blerina Gkotse
  • Boris Militsyn
  • Brendan Whelan
  • Brian Pogue
  • Bruni Christelle
  • Bryan Muir
  • Cairo Caplan
  • Cameron Robertson
  • Carlo Rossi
  • Carlos Hidalgo
  • Cecilia Cuitino
  • Ceferino Obcemea
  • Celeste Fleta
  • Charbel Koumeir
  • Charles Limoli
  • Chiara De Lucia
  • Chloé Lahaye
  • Christophe Thiebaux
  • Christopher Barty
  • Christopher Barty
  • Chunguang Jing
  • Cinzia De Angelis
  • Claude Bailat
  • Claudio Serpico
  • claudio zucchetti
  • Colleen DesRosiers
  • Concepción Oliver Amorós
  • concetta ronsivalle
  • Consuelo Guardiola
  • Corey Lehmann
  • Cristina Balan
  • Cristina Oancea
  • Cynthia Aristei
  • Cécile Rimbault
  • Dai Wu
  • Daiki Hayakawa
  • Daniel Berger
  • Daniel Esperante Pereira
  • Daniela Poppinga
  • David Alesini
  • David Bradley
  • David Gladstone
  • David Horvath
  • David Menichelli
  • David Pavel Juarez Lopez
  • Davide Gamba
  • Debasish Das
  • Deepa ANGAL-KALININ
  • Denis Dauvergne
  • Derek DeScioli
  • Diana Bachiller Perea
  • Dirk Bartkoski
  • Dirk Verellen
  • Domenico Vicinanza
  • Dragos Constantin
  • Dukagjin Blakaj
  • Elaine Seddon
  • Elena Benedetto
  • Elke Beyreuther
  • Ellina Macaeva
  • Emil Schueler
  • Emilie BAYART
  • Emilio Nanni
  • emily bo yan chan
  • Emma Snively
  • Emmanuel Rio
  • Eric Abel
  • Erik Traneus
  • Eugene Tan
  • Eva Bogaerts
  • Evangelos Gazis
  • Evaristo Cisbani
  • Faustino Gomez
  • Faya Wang
  • Federico Colecchia
  • Federico Keszti
  • Federico Ravotti
  • Fenompanirina Andrianala
  • Florian Burkart
  • Florian Kroll
  • Francesca Bisello
  • Francesco Romano
  • Francisco Torrens
  • Frank Stephan
  • François Vander Stappen
  • Frederic Zenhausern
  • G M
  • Gabriele Maria Grittani
  • Gabriele Parisi
  • Gabriella Mifsud
  • Gerard McMonagle
  • Gerardo D'Auria
  • Gianluca Ingrosso
  • Gilberto Nakamura
  • Giulia Bazzano
  • Giuliana Tromba
  • Giuseppe D'Avenio
  • Giuseppe Felici
  • Giuseppe Pezzullo
  • Giuseppe Schettino
  • Gohar Tsakanova
  • Gregor Loisch
  • Grigori Feofilov
  • Guan Shu
  • Guangjun Li
  • Guillaume Martinet
  • Hannah Wanstall
  • Hannes Dinter
  • Hans Priem
  • Harold Swartz
  • Harris Targovnik
  • Hayo Zutz
  • Hendrik Jansen
  • Hermann Kolanoski
  • Hikmet Bursali
  • Houda Kacem
  • Houjun Qian
  • hugo marroux
  • Igor Syratchev
  • Immaculada Martínez-Rovira
  • Inga Pfeffer
  • Ioannis Petridis
  • Iuliana Toma-Dasu
  • Jacinta Yap
  • Jack Kasahara
  • Jacob Van Dyk
  • James Clayton
  • James Good
  • James Renaud
  • Jan Knoll
  • Jan-Hendrik Arling
  • Javier Barranco
  • Jean Bourhis
  • Jean-François Germond
  • Jeannette Jansen
  • Jeffrey Tuan
  • Jeffrey Woollard
  • Jens Knobloch
  • Jeremy Brison
  • Jessica Fleming
  • Jessica Perez
  • Jessica Scifo
  • Jhonnatan Osorio
  • Jia-Ling Ruan
  • Jiahang Shao
  • Jiaru Shi
  • Jim Clarke
  • Joao Seco
  • Johannes Bernhard
  • John Allen
  • Jolyon Hendry
  • jose lopez torrecilla
  • Josefine Metzkes-Ng
  • Joseph Bateman
  • Joshua McNeur
  • José Paz Martín
  • Juan Pablo Cruz Bastida
  • Judith Meza
  • JUIMEI HSU
  • Julien Forthomme
  • juliette thariat
  • Jun Hao Phua
  • Jérémie Bauche
  • Jürgen Roth
  • Karolina Kokurewicz
  • Kenneth Brooks
  • Kevin Cassou
  • Kimberly Mahler
  • Kiran Beera
  • Kirk Bertsche
  • Klaus Floettmann
  • Kristi Glover
  • Kristina Small
  • Kristjan Poder
  • Kristoffer Petersson
  • Kwangzoo Chung
  • Lasitha Senadheera
  • Laurence Wroe
  • Leonello Servoli
  • Leonida Antonio Gizzi
  • Lianliang Ma
  • Linda Kadi
  • Louie Hancock
  • Luca Labate
  • Luca Piersanti
  • lucia giuliano
  • Lucian Hotoiu
  • Lucie Portier
  • Lucy Whitmore
  • Ludovic De Marzi
  • Luigi Faillace
  • Luiz Fernando Albuquerque Barbosa
  • Luke Aidan Dyks
  • Luyao Xu
  • Magdalena Bazalova-Carter
  • Mahbubur Rahman
  • Mahsa Servati
  • Manish Bagre
  • Manjit Dosanjh
  • Maram Othman
  • Marc Verderi
  • Marcel van Herk
  • Marco Bellaveglia
  • Marco Borghesi
  • Marco Schwarz
  • Maria Antonella Tabocchini
  • maria bisogni
  • Maria de los Angeles Faus-Golfe
  • Maria Trachsel
  • marie dutreix
  • Marie-Catherine Vozenin
  • Marie-Laure Gallin-Martel
  • Mariusz Sapinski
  • Marjorie Juchaux
  • Markus Aicheler
  • Matteo Volpi
  • Matthias Gross
  • Melvin Chew
  • Michael Fix
  • Michael Lafky
  • Michael Lerch
  • Michael McManus
  • Michael Taylor
  • Michele Siggel-King
  • Micol De Simoni
  • Miguel Cámara
  • Miguel Pretelli
  • Mikhail Krasilnikov
  • Mimoza Ristova
  • Ming Tsuey Chew
  • Ming Tsuey Chew
  • Moeava Tehei
  • Mohammad Salehpour
  • Mohammed Abujami
  • Monia Vadrucci
  • Namra Aftab
  • Nathan Roche
  • Natthawut Chaisueb
  • Navrit Johan Singh Bal
  • Nawin Juntong
  • NICOLAE VERGA
  • Nicolas Rosuel
  • Nilendu Gupta
  • Norbert Tesch
  • Nuria Fuster-Martínez
  • Oliver Hupe
  • Olivia Drayson
  • Olivian Savencu
  • Osip Lishilin
  • Othmane Bouhali
  • Ourania Sidiropoulou
  • Oznur Apsimon
  • P. Jack Hoopes
  • Pablo Martinez Reviriego
  • Pascal Girault
  • Patricia Pina
  • Patrik Jorge
  • Patrizia De Maria
  • Paul Barghouth
  • Paul Bennetto
  • Paul Smith
  • Paula Barrera Gomez
  • Pedro Morales Sanchez
  • Peregrin van den Elzen
  • Peter Gruebling
  • Peter Maxim
  • Peter Peier
  • Peter Ratoff
  • Petya Georgieva
  • Philip Nicholas Burrows
  • Philippe THOUVENIN
  • Pierre Everaere
  • Pierre Montay-Gruel
  • Pooneh Saidi Bidokhti
  • Prach Boonpornprasert
  • Rachel Delorme
  • Radu Alin Vasilache
  • Rafael Colmenares
  • Raffael Niemczyk
  • Raffaella Geometrante
  • Rakesh Manjappa
  • Ralf Dreindl
  • Ralf-Peter Kapsch
  • Ralph Young
  • Ramish Ashraf
  • Ran Mackay
  • raphael serduc
  • Raphaël Moecki
  • Raquel Muñoz Horta
  • Rebecca Auchettl
  • Reem Ahmad
  • Regina Alexandra Rochow
  • Remy Kinj
  • Richard Amos
  • Ricky Sharma
  • Rob Edgecock
  • Robert Miller
  • Roberto Corsini
  • Roger Cashmore
  • Roger Jones
  • Roger Ruber
  • Rohan Dowd
  • Ron Leavitt
  • Rongxiao Zhang
  • Roxana Tarkeshian
  • Rudi Labarbe
  • Saba Hussain
  • Sam Flynn
  • Sami Tantawi
  • Sandro Rossi
  • Sara Morales Vigo
  • Sebastian Adamczyk
  • Serena Psoroulas
  • Sergei Nemnyugin
  • Sergey Antipov
  • Shadike Saitiniyazi
  • Shankar Lal
  • Simeon Chinedu Aruah
  • Simon Busold
  • Simon Jolly
  • Sofiia Forostenko
  • Sonali Bhatnagar
  • Sonali Bhatnagar
  • Song FENG
  • Sophie Chance
  • sophie Chiavassa
  • Sophie Heinrich
  • Stavros Melemenidis
  • Stefan Choroba
  • Steinar Stapnes
  • Stephanie Corde
  • Stevan Vrbaski
  • Steven Worm
  • Sung Yong Park
  • Susan Leech O'Neale
  • Suzie Sheehy
  • Séverine Rossomme
  • Tanjil Amin
  • Tessa Charles
  • Till Böhlen
  • Tobias Weilbach
  • Ugur Akgun
  • Ulrich Schramm
  • Valentina Malconi
  • VALERIA ROSSO
  • Valery Dolgashev
  • Veljko Grilj
  • Vera Korchevnyuk
  • Verdi Vanreusel
  • victor malka
  • VIKTORIA MESKOVA
  • Vincent Ehrhardt
  • Vincent Favaudon
  • Vincenzo Patera
  • Virginia Marin Anaya
  • Vladimir Zherebchevsky
  • Walter Wuensch
  • Warren Kilby
  • Wei Meng
  • Wencheng Fang
  • Whitney Curtis
  • Wilfrid Farabolini
  • Willi Kuropka
  • William Shields
  • Wim Leemans
  • Woo-Yoon Park
  • Xiangkun Li
  • Xiaowei Wu
  • Xueying Lu
  • Yahya Tayalati
  • Yana Gurimskaya
  • Yannick Arnoud
  • Yasar Onel
  • Ye Chen
  • Ye Zou
  • yolanda prezado
  • Yoonwoo Hwang
  • Yuliang Jiang
  • Zhen Liu
  • Zhiling Chen
CLIC Project Office
    • 3:00 PM 4:15 PM
      State of the Art
      Convener: Roberto Corsini (CERN)
      • 3:00 PM
        Clinical perspectives for FLASH therapy 20m
        Speaker: Jean Bourhis (CHUV)
      • 3:25 PM
        Novel high-gradient accelerators for radiotherapy and imaging 20m
        Speaker: Emilio Nanni (SLAC)
      • 3:50 PM
        Dosimetry of electron beams - challenges and possible solutions for VHEE and FLASH 20m
        Speaker: Andreas Schüller (PTB)
    • 4:15 PM 4:25 PM
      Welcome Speech 10m
      Speaker: Roberto Corsini (CERN)
    • 4:25 PM 4:35 PM
      Break & Group photo 10m
    • 4:35 PM 5:35 PM
      Mechanism and Innovation for FLASH RT
      Convener: Manjit Dosanjh
      • 4:35 PM
        Neuroprotective effects of FLASH-RT in the juvenile and adult brain 15m
        Speaker: Charles Limoli (University of California, Irvine)
      • 4:55 PM
        Tumor response to FLASH-RT 15m
        Speaker: Marie-Catherine Vozenin (CHUV)
      • 5:15 PM
        Electron dose rate and oxygen depletion protect zebrafish embryo from radiation damage 15m
        Speaker: Elke Beyreuther (Helmholtz-Zentrum Dresden - Rossendorf)
    • 5:35 PM 5:45 PM
      Break 10m
    • 5:45 PM 6:45 PM
      New indications and hot topics
      Convener: Angeles Faus-Golfe (Université Paris-Saclay (FR))
    • 6:45 PM 6:50 PM
      Closing 5m
    • 3:00 PM 4:00 PM
      Facilities description, current and planned ones (Chaired by Claude Bailat)
      Convener: Claude Bailat (CHUV)
      • 3:00 PM
        CLEAR for Radiotherapy Research 15m
        Speaker: Wilfrid Farabolini (Université Paris-Saclay (FR))
      • 3:20 PM
        Full energy beam exploitation possibilities on CLARA at Daresbury Laboratory 15m
        Speaker: Deepa Angal-Kalinin (STFC)
      • 3:40 PM
        High-gradient RF systems for compact accelerators 15m
        Speaker: Walter Wuensch (CERN)
    • 4:00 PM 4:10 PM
      Break & Group Photo 10m
    • 4:10 PM 5:10 PM
      Facilities description, current and planned ones (Chaired by Charles Limoli)
      • 4:10 PM
        New FLASH radiation therapy R&D options at PITZ 15m
        Speaker: Frank Stephan (DESY)
      • 4:30 PM
        Radiation biology with laser-accelerated electrons at LOA 15m
        Speaker: Alessandro Flacco (ENSTA)
      • 4:50 PM
        Novel high-gradient accelerators for radiotherapy and imaging 15m
        Speaker: Bill Loo (Stanford University)
    • 5:10 PM 5:20 PM
      Break 10m
    • 5:20 PM 6:20 PM
      Dosimetry and Detectors (Chaired by Marie-Catherine Vozenin)
      • 5:20 PM
        Diamond-based detector development for pulsed beam monitoring for medical applications 15m
        Speaker: Marie-Laure Gallin-Martel (CNRS)
      • 5:40 PM
        Dosimetry of particle beams with ultra-high pulse dose rates 15m
        Speaker: Anna Subiel (NPL)
      • 6:00 PM
        The challenges of Ultra high dose rate dosimetry for preclinical irradiation 15m
        Speaker: Claude Bailat (CHUV)
    • 6:20 PM 6:30 PM
      Break 10m
    • 6:30 PM 7:30 PM
      Treatment Planning, Modelling and Imaging (Chaired by Roger Jones)
    • 7:30 PM 7:35 PM
      Closing 5m
    • 3:00 PM 4:10 PM
      Accelerators R&D and Technologies for medical (Chaired by Frank Stephan)
      • 3:00 PM
        Compact high-energy electron accelerator at Tsinghua University 15m
        Speaker: Jiaru Shi
      • 3:20 PM
        Sources for high dose rate electron and proton irradiation at the ELBE center Dresden 15m
        Speaker: Ulrich Schramm
      • 3:40 PM
        Research and Development of High Efficiency, High Gradient Accelerator Systems for VHEE at SLAC 15m
        Speaker: Emma Snively (SLAC)
      • 4:00 PM
        Experience with electron linear accelerators for low-energy FLASH Intraoperative RT with perspectives on VHEE beams 10m
        Speaker: Luigi Faillace (University di Roma)
    • 4:15 PM 4:25 PM
      Break 10m
    • 4:25 PM 6:02 PM
      Industries for medical (Chaired by Gerardo D'Auria and Sami Tantawi)
      • 4:25 PM
        Outline of the roadmap involved in taking a working design through to something that is approved to treat clinical 5m
        Speaker: John Allen (ELEKTA)
      • 4:35 PM
        Perspectives for industrial superconducting accelerators for isotope production and radiation therapy 5m
        Speaker: Claudio Serpico
      • 4:45 PM
        Progress status for the 40 MeV Rhodotron and the new very high dose rate 10 MeV Flash platform at Aérial/Feerix 5m
        Speaker: Jeremy Brison (IBA)
      • 4:55 PM
        Inverse Compton scattering X-ray source optimized for radiotherapy 5m
        Speaker: Benjamin Hornberger (Lynceantech)
      • 5:05 PM
        Compact linac design for FLASH radiation therapy 5m
        Speaker: Arundhuti Ganguly (TiBaRay)
      • 5:15 PM
        High Frequencry (12 GHz) RF generated electrons (100 MeV) 5m
        Speaker: Christopher Barty (Lawrence Livermore National Laboratory)
      • 5:25 PM
        The challenge of high dose rate for ionisation chambers 10m
        Speaker: Daniela Poppinga (PTW)
      • 5:35 PM
        Capabilites of the AWA facility for potental medical applications 7m
        Speaker: Jing Chunguang
      • 5:45 PM
        Single electron imaging of samples using multiple coulomb scattering 7m
        Speaker: Hendrick Jansen
      • 5:55 PM
        Plans for growth in accelerator physics in Australia: medical and VHEE applications 7m
        Speaker: Suzie Sheehy (University of Melbourne)
    • 6:05 PM 6:15 PM
      Break 10m
    • 6:15 PM 7:30 PM
      Where are we going? Which experiments/facilities are needed? (Chaired by Jean Bourhis)
      Convener: Manjit Dosanjh
      • 6:15 PM
        Main topics 15m
        Speakers: Manjit Dosanjh, Angeles Faus-Golfe
      • 6:30 PM
        Roundtable discussion 45m
        Speakers: Manjit Dosanjh, Angeles Faus-Golfe
      • 7:15 PM
        Concluding remarks 15m
        Speakers: Manjit Dosanjh, Angeles Faus-Golfe