Simulation of Prompt Gamma Imaging in Hadron Therapy

20 Sept 2021, 18:05
1h 55m
Poster report Section 8. Nuclear medicine. Poster session (Mixed)

Speaker

Sergei Nemnyugin (Saint Petersburg State University)

Description

Hadron therapy is efficient method of cancer treatment due to phenomenon of the Bragg peak which cause precise localization of the dose absorbed by biological tissues [1, 2]. It improves quality of life of a patient minimizing action of therapeutic beam on healthy part of body. Transversal scattering of the beam is less than that for other kinds of radiotherapy.
Hadron therapy has some shortcomings. It is highly sensitive to unavoidable errors of preparing the treatment plan and its realization. Influence of some kinds of errors or uncertainties cannot be accounted in simulation or theoretic considerations. So experimental or "online" techniques are absolutely required to control the hadron therapy treatment process and especially stopping region of protons or carbon ions from the therapeutic beam [3]. Positron emission and computer tomography methods may be used to control the treatment process. Prompt Gamma Imaging (PGI) method is relatively new and perspective technique, which may be very efficient. Our study consider dependence of the beam parameter, Bragg peak localization and distribution parameters of secondary particles in the PGI method. Reference points of distribution are defined which may be used to define Bragg peak position. Proton and carbon ions have been considered. FLUKA and GEANT4 packages are used for simulation.
Bibliography
1. R.R. Wilson., Radiology 47, p.487, (1946).
2. Radhe Mohan, David Grosshans., Advanced Drug Delivery Reviews 109, p.26 (2017).
3. Antje-Christin Knopf, Antony Lomax., Phys. Med. Biol. 58, p.131 (2013).

Primary authors

Dr Kirill Primak (Saint-Petersburg State University) Dr Polina Golubeva (Saint-Petersburg State University) Sergei Nemnyugin (Saint Petersburg State University)

Presentation materials