Speaker
Description
Lab rats and rabbits are irrepleceable models for study of the ortopedic pathologies.
Traditional analysis of these pathologies is based on postmortem histological analysis or X-
ray or invasive sampling, however modern monitoring of orthopedic pathology and
regeneration needs the smart and noninvasive methods for quantification of the motility of
the limbs and organism. Advances in imaging technologies have enhanced our posibilities to
quantify the typical movement of the organism.
Lab animals were hold in typical lab cage. We developed an autonomous optical setup which
recorded animal position and displayed the trajectory and typical characteristic of the
movement (speed, acceleration, shading of the walls of cage, rocognition of biorhytmic
period).
The system was based on the HD 10 fps camera. Export of the frames was commited to
OpenCV and mathematical conversion of motion to x-y coodinates was curbed by set of
Python utlilities.
Comparison of animals with deffects and healthy animals gives basic criterion for automatic
recognition of patholgical state and basic criterion for evaluation of regeneration process.
Upgrade of these biometric system should be used also for clinical and home rehabilitation in
the future.
Supported by the Ministry of Education, Youth and Sports project “FIT” (Pharmacology,
Immunotherapy, nanoToxicology) CZ.02.1.01/0.0/0.0/15 003/0000495