ICTR-PHE 2014

10 Feb 2014, 12:00 → 14 Feb 2014, 16:30 Europe/Zurich

Centre International de Conferences de Geneve (CICG)

Jacques BERNIER, Manjit Dosanjh

A conference that brings together the International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe.




Journalists can check the accreditation procedure

Please check the ICTR-PHE 2014 main website for more information on the conference itself (venue, committees, sponsorship)

Monday 10 February ¶

12:00 Lunch

1 Welcome addresses¶

Speakers: Jacques Bernier, Manjit Dosanjh, Representative of the Geneva state, Rolf Heuer

The Higgs boson and our life¶

Conveners: Jacques Bernier, Rolf-Dieter Heuer

2 The Higgs boson and our life¶

Speaker: Fabiola Gianotti

Slides 01_FabiolaGianotti.pdf

Radiobiology¶

Conveners: Kevin Prise, Marco Durante

3 Ion Beam Radiobiology: From the Lab to the Clinic¶

Speaker: Eleanor Blakely

Slides 02_EleanorBlakely.pdf

4 International Cancer Expert Corps (ICEC)¶

Speaker: Norman Coleman

5 New challenges for biologically adapted ion beam treatment planning: single and multi-ion approaches¶

Speaker: Emanuele Scifoni

Slides Scifoni-ICTR-PHE2014-OK.pdf

6 RBE and DNA damage variation along monoenergetic and modulated Bragg peaks of a 62 MeV therapeutic protons beam¶

Speaker: Kevin Prise

Slides 04_KevinPrise.pdf

7 Influences of aberrant mitochondrial DNA in cancer and cancer therapy¶

Speaker: Marike van Gisbergen

8 Hpv Status and Effect on Radiosensitivity in Head and Neck Cancer Tumor Xenografts¶

Speaker: Brita S Sørensen

16:00 Coffee

Radiobiology¶

Conveners: Kevin Prise, Marco Durante

9 Rectal cancer and fractionation sensitivity in the neo-adjuvant radiation therapy setting: a project of meta-analysis and radiobiological modeling from individual patient data in randomized and observational data-sets¶

Speaker: Raymond Miralbell

10 A Biomedical Research Facility at CERN based on the Low Energy Ion Ring¶

Speaker: Adriano Garonna

Slides 02_AdrianoGaronna.pdf

Nuclear Medicine¶

Conveners: Irene Virgolini, Ulli Koster

11 Radiochemical aspects of radionuclide therapies¶

Speaker: Helmut Maecke

12 ²¹²Pb-labeled mAbs targeting CEA or HER2 during α-RIT of small peritoneal carcinomatosis – Dose effect relationship?¶

Speaker: Jean-Pierre Pouget

13 152/161Tb-DOTA-RM6 biodistribution studies in prostate cancer bearing SCID mice and 149Tb sources from CERN-MEDICIS¶

Speaker: Thierry Stora

14 A radionuclide generator of Erbium-165, an isotope for Auger Therapy¶

Speaker: Gregory Severin

Tuesday 11 February ¶

Nuclear Medicine¶

Conveners: Thomas Beyer, Ulli Koster

15 Clinical experience with radionuclide therapies¶

Speaker: Irene Virgolini

16 From bench to bedside: development and early clinical results of 188Re-SSS/Lipiodol for HCC treatment¶

Speaker: Nicolas Lepareur

17 PIP: a compact recirculating accelerator for the production of medical isotopes¶

Speaker: Adina Toader

18 Gamma Probe Based on Scintillation Crystal and Silicon Photomultiplier¶

Speaker: Konstantin Zhukov

19 Preclinical studies and radiopharmaceutical developments with 64Cu produced by ARRONAX facility¶

Speaker: Mickael Bourgeois

10:00 Coffee Break

Detectors & Imaging¶

Conveners: Alberto Del Guerra, Denis Dauvergne

20 From CERN to PET/MR¶

Speaker: David Townsend

Slides 01_DavidTownsend.pdf

21 Software challenges and opportunities for multidisciplinary PET/CT and PET/MR imaging¶

Speaker: Dimitris Visvikis

Slides 02_DimitrisVisvikis.pdf

22 Prompt gamma imaging of proton pencil beams at clinical beam current¶

Speaker: Julien Smeets

23 Prediction of β+-activity distributions from PT-PET by means of a yield approach¶

Speaker: Stephan Helmbrecht

24 ProXY – High performance monolithic pixel tracker for proton tomography¶

Speaker: Piero Giubilato

25 The recent developments of the FLUKA Monte Carlo code oriented to its applications in Hadrontherapy¶

Speaker: Paola Sala

12:30 Lunch

Detectors & Imaging¶

Conveners: Alberto Del Guerra, Denis Dauvergne

26 Different detector concepts for several imaging scenarios: from hadrontherapy monitoring to clinical imaging¶

Speaker: Paola Solevi

27 An integrated monitoring system for the on-line assessment of particle therapy treatment accuracy¶

Speaker: Vincenzo Patera

Slides 02_VincenzoPatera.pdf

28 Development of Advanced Quality Assurance Instrumentation for Hadrontherapy¶

Speaker: David Watts

Slides 03_DavidWatts.pdf

New Technologies¶

Conveners: Anthony Lomax, Wolfgang Enghardt

29 Novel detectors for range assessment in particle therapy¶

Speaker: Peter Thirolf

Slides 01_PeterThirolf.pdf

30 The ELIMED (Multidisciplinary and Medical applications at the ELI-Beams) network perspectives for laser driven beam applications¶

Speaker: Andrea Attili

31 Harnessing laser-plasma accelerated ion beams for applications using Gabor lenses¶

Speaker: Christopher Hughes

32 Positron emission tomography (PET) isotope production from laser-driven proton¶

Speakers: John Wong, Kai Ding

33 A novel TOF-PET detector based on organic scintillators¶

Speaker: Pawel Moskal

15:45 Coffee Break

New Technologies¶

Conveners: Anthony Lomax, Wolfgang Enghardt

34 Requirements from Oncology to Imaging Technologies¶

Speaker: Heinz-Peter Schlemmer

35 Potential of Detection of fast Cherenkov Photons for Improved Time of Flight Positron Emission Tomography¶

Speaker: Stefan Brunner

36 Experimental characterization of acoustic detection and imaging for Bragg peak localization in proton therapy¶

Speaker: Katia Parodi

37 A new elastic image fusion model for lung deformation simulation in 4D dose calculations¶

Speaker: Stefan Milz

38 Physics is beautiful and useful¶

Speaker: Ugo Amaldi (TERA Foundation (IT))

Slides UgoAmaldi-publictalk.pdf

Video in CDS Video in CDS

20:00 Cocktail

Wednesday 12 February ¶

ESTRO lecture¶

Convener: Jean Bourhis

39 Individualized Radiation Oncology – harnessing clinics, biology and high technology¶

Speaker: Michael Baumann

Plenary session¶

Conveners: Jacques Bernier, Manjit Dosanjh

40 Health implications and applications in space¶

Speaker: Christer Fuglesang

41 The convergence of science - the way to develop novel radiation oncology technologies for the future¶

Speaker: Dag Rune Olsen

10:00 Coffee Break

Plenary session¶

Conveners: Jacques Bernier, Manjit Dosanjh

42 Current status of Carbon Ion Radiotherapy at NIRS¶

Speaker: Hirohiko Tsujii

43 Radioisotopes - the "fuel" for nuclear medicine¶

Speaker: Ulli Koster

44 Medical applications at CERN¶

Speaker: Steve Myers

12:00 Lunch

New Insights into molecular mechanisms of radio-curability¶

Convener: Conchita Vens

45 New insights into the complexities of NHEJ and HR repair¶

Speaker: Simon Powell

46 Homologous recombination deficiency and radio-curability in mouse models for BRCA1/2-deficient breast cancer¶

Speaker: Sven Rottenberg

47 Mechanism of HR dysfunction in single dose radiotherapy¶

Speaker: Zvi Fuks

Optimizing treatment planning and delivery¶

Convener: Rahde Mohan

48 New insights in IGRT for prostate cancer¶

Speaker: Marcel Van Herk

Slides 01_MarcelVanHerk.pdf

49 Adaptive radiotherapy¶

Speaker: Vincent Gregoire

50 New health technologies and evidence-based medicine¶

Speaker: Soren Bentzen

14:15 Coffee Break

Hadrons¶

Conveners: Manjit Dosanjh, Norman Coleman

51 Carbon Ion Therapy: Actual and Future Strategies at HIT¶

Speaker: Jurgen Debus

52 Present status of CNAO¶

Speaker: Roberto Orecchia

53 Proton Radiation Therapy: Current Status of Clinical Trials¶

Speaker: Thomas Delaney

Slides 03_ThomasDeLaney.pdf

54 France HADRON: national infrastructure for hadrontherapy research including ETOILE, ARCHADE and protontherapy centers¶

Speaker: Jacques Balosso

Slides 04_JacquesBalosso.pdf

Proffered papers - Physics I¶

Conveners: David Townsend, Thomas Beyer

55 The development of a low energy facility for clinical trials of Boron Neutron Capture Therapy¶

Speaker: Rob Edgecock

56 Interstitial Detectors for Synchronized Radiation Quality¶

Speaker: Giulio Magrin

Slides 02_GulioMagrin.pdf

57 An innovative on-line beam-monitoring detector based on the emission of secondary electrons¶

Speaker: Saverio Braccini

58 Radiotherapy Dose Monitoring to Low-Dose Morphologic Imaging with Scanned Megavoltage X-rays¶

Speaker: Paulo Crespo

59 Data models for the Compton camera acquisition and their influence on the reconstructed images¶

Speaker: Voichita Maxim

Slides 05_VoichitaMaxim.pdf

60 Detection of ionizing radiation by intrinsic optical fiber sensors: preliminary results¶

Speaker: Laura Cella

Slides 06_LauraCella.pdf

61 First investigations of Ultra-Thin 3D silicon detectors as microdosimeters¶

Speaker: Celeste Fleta

62 Frequency difference electrical impedance tomography for imaging lung tumour¶

Speaker: Chuan Li Yang

63 A novel dual-modality optical tomography and x-ray system for small animal radiation research platform¶

Speaker: Ken Kang Hsin Wang

64 Digital Image Processing Techniques for Application in a Microbeam End-Station Microscopy¶

Speaker: Antonios Georgantzoglou

Proffered papers - Biology I¶

Conveners: Bleddyn Jones, Kevin Prise

65 DCE-MRI and DCE-US quantification in CWR22 prostate tumour xenografts¶

Speaker: Natalia Arteaga-Marrero

66 Antitumor activity of combination therapy with TH-302 and irradiation in a rat rhabdomyosarcoma model¶

Speaker: Sarah Peeters

67 Development of a novel ELISA for detecting inducible Hsp70 in serum¶

Speaker: Stephanie Ertl

68 Advancing the small animal radiation research platform for pre-clinical radiation research¶

Speaker: John Wong

69 Evaluation of Late Toxicity Risk for RT Patients through Geant 4 Simulation of X-Ray Dose Deposition¶

Speaker: Frederic Brochu

70 Log file based dose calculations as a quality assurance tool in scanned beam proton radiotherapy¶

Speaker: Gabriel Meier

71 A Novel Radioguided Surgery Technique Exploiting - decays¶

Speaker: Riccardo Faccini

72 Investigation of irregular motion influence for future 4D In-beam PET imaging¶

Speaker: Yuan Tian

73 Ongoing investigations on ion-based radiography and tomography¶

Speaker: Lorena Magallanes

Proffered papers - Physics II (Hadrons)¶

Conveners: Guido Baroni, Katia Parodi

74 Initial Qualification of the Irradiation Uncertainties in Ion Beam Therapy of Prostate Cancer¶

Speaker: Antoni Rucinski

75 Can particle beam therapy be improved using helium ions? - A treatment planning study focusing on pediatric patients¶

Speaker: Barbara Knaeusl

76 MCTP: a new Monte Carlo-based treatment planning tool for hadrontherapy¶

Speaker: Giusseppe Battistoni

Slides 03_GiusseppeBattistoni.pdf

77 PlanIt: Planning Ion therapy open platform for treatment plans testing and comparing¶

Speaker: Faiza Bourhaleb

78 Robustness of range prediction in proton therapy using prompt gamma emission¶

Speaker: Fiere Janssen

79 Simulation of Hadrontherapy In-beam monitoring at CNAO with the INSIDE detector¶

Speaker: Piergiorgio Cerello

Slides 06PieriorgioCerello.pdf

80 Evaluation of existing ripple filter designs for clinical use at the MedAustron ion beam therapy facility¶

Speaker: Loic Grevillot

81 The (non-) detectability of failures in motion mitigated ion beam delivery by means of in-beam PET¶

Speaker: Kristin Stützer

82 Assessment and improvements of Geant4 models in the context of prompt-gamma hadrontherapy monitoring¶

Speaker: George Dedes

83 Monte Carlo modelling of whole-body secondary cancer risk for conventional and emergent radiotherapy¶

Speaker: Richard Hugtenburg

19:00 Gala Dinner

Thursday 13 February ¶

GH Fletcher Lecture¶

Convener: Ritsuko Komaki

84 Host and Tumor Immunity: Local and Systemic Opportunities to Enhance Tumor Curability by Radiotherapy¶

Speaker: Ralph Weichselbaum

From new therapeutic targets to personalized treatment¶

Convener: Søren Bentzen

85 Identification of new therapeutic targets¶

Speaker: Conchita Vens

86 Single-dose radiotherapy: from learning curve to long-term clinical outcome¶

Speaker: Carlo Greco

87 From bench to bedside: experience of the glioblastoma model for the optimization of radiosensitization¶

Speaker: Elizabeth Moyal

Radiotherapy - Hypoxic modification of radiotherapy¶

Convener: Marianne Nordsmark

88 Hypoxia-induced gene expression¶

Speaker: Marianne Koritzinsky

89 Impact of tumor autophagy on solid tumors response to IR: role of the tumor stroma¶

Speaker: Eric Deutsch

90 Hypoxia: where to go from here?¶

Speaker: Jens Overgaard

10:05 Coffee Break

EORTC symposium¶

Conveners: Philippe Maingon, Sofia Rivera

91 The new business model of the EORTC¶

Speaker: Emad Shash

92 The Radiation Oncology Group of the EORTC: from the past to the future¶

Speaker: Philippe Maingon

93 The new drug and radiotherapy working party¶

Speaker: Conchita Vens

94 An example of the integrated model: the EORTC DAHANCA-1219 trial¶

Speaker: Vincent Gregoire

Proffered papers - Biology II¶

Conveners: Raj Jena, Wolfgang Dörr

95 Enhanced RBE of sub-micrometer focused low-LET protons¶

Speaker: Thomas Schmid

96 Expression of common or species specific DNA damage-repair pathway related genes in thymus of low-dose-rate irradiated AKR/J and ICR mice¶

Speaker: Hee Sun Kim

97 [18F] HX4 PET imaging of tumour hypoxia in HNSCC patients¶

Speaker: Karen Zegers

98 Inhibition of tumour growth using the small molecule Cathepsin L inhibitor, KGP94¶

Speaker: Thomas Wittenborn

99 Delayed and Persistent Response of Human Mitochondria after Single Exposure to 0.5 to 4 Gy of Gamma Radiation¶

Speaker: Winnie Kam

100 Dosimetric considerations to determine the optimal technique for localized prostate cancer¶

Speaker: Peter Kuess

Slides 06_PeterKuess.pdf

101 Auger electron emitters labeled to monoclonal antibodies trigger cell membrane-mediated bystander effects¶

Speaker: Jean-Pierre Pouget

102 Comparing Ion Computed Tomography under clinical constraints¶

Speaker: David Hansen

Proffered papers - Physics III¶

Conveners: Denis Dauvergne, Ken Peach

103 Ultimate Time Resolution in Time-of-Flight PET¶

Speaker: Paul Lecoq

104 Ultrafast PET Detectors Based on Digital SiPMs and Their Use in In-Situ PET and Prompt Gamma Ray Imaging¶

Speaker: Dennis Schaart

Slides 02_DennisSchaart.pdf

105 4D Dose calculations and 4D PET image reconstruction using deformable tetrahedral models of moving organs¶

Speaker: Petre Manescu

106 Motion compensated reconstructions in PET-based ion beam treatment verification for moving target¶

Speaker: Chiara Gianoli

107 Usage of long axial crystals for PET applications: the AX-PET demonstrator and beyond¶

Speaker: Chiara Casella

Slides 05_ChiaraCasella.pdf

108 Realistic on-the-fly dose calculation for low energy X-rays Intra-Operative Radiation Therapy¶

Speaker: Marie Vidal

109 A single device for mechanical and radiation Quality Assurance measurements of medical accelerators¶

Speakers: Ernesto Valverde, John Wong

110 A combined electrical impedance tomography and cone beam CT for radiation therapy monitoring¶

Speaker: Manuchehr Soleimani

Proffered papers - Biology III¶

Conveners: Raj Jena, Wolfgang Dörr

111 Oxygen ions achieve better tumour control probability in hypoxic tumours than carbon ions do¶

Speaker: Niels Bassler

112 Direct evaluation of ion beam radiobiological parameters from clinical data: an alternative approach to the RBE¶

Speaker: Andrea Attili

113 Equivalent uniform dose (EUD) based biological optimization for carbon ion therapy¶

Speaker: Sarah Brüningk

Slides 03_SarahBrüningk.pdf

114 Variance Based Sensitivity Analysis of Biological Uncertainties in Carbon Ion Therapy¶

Speaker: Florian Kamp

Slides 04_FlorianKamp.pdf

Proffered papers - Physics IV (Hadrons)¶

Convener: Sandro Rossi

115 TOF-PET scanner configurations for quality assurance in proton therapy: a patient case study¶

Speaker: Peter Dendooven

Slides 01_Dendooven.pdf

116 Implementation of a GPU Monte Carlo protons transport code for dose calculations: methods and challenges¶

Speaker: Daniel Maneval

Slides 02_DanielManeval.pdf

117 Fast pencil beam dose calculation for hadron therapy on GPU¶

Speaker: Joakim Da Silva

118 Parameterization of lateral dose profiles for proton therapy application at CNAO¶

Speaker: Martina Mori

Profferred papers - Radiotherapy I¶

Convener: Marcel Verheij

119 Modelling acute urinary toxicity after radiotherapy for prostate cancer¶

Speakers: Tiziana Rancati, Viviana Caillo

120 Mediators associated to the inflammatory response in prostate cancer patients undergoing RT: preliminary results¶

Speaker: Bedini Nice

121 Daily variation in rectal size and position during prostate radiotherapy measured from helical tomotherapy CT scans¶

Speaker: Jessica Scaife

122 Clinical experience with adaptive radiotherapy for muscle invasive bladder cancer¶

Speaker: Anne Vestergaard

Slides Vestergaard_ICTR2014.pdf

12:30 Lunch

ESO Session - E. van der Schueren Award¶

Convener: Alberto Costa

123 The ART of translation¶

Speaker: Marcel Verheij

Symposium in honour of Prof. Kian K. Ang- Translational research: the example of head and neck cancer¶

Convener: Ritsuko Komaki

124 Eulogy of Professor Kian K. Ang¶

Speaker: James Cox

Slides 01_JamesCox.pdf

125 Milestones of Pr Kian Ang’s scientific contribution¶

Speaker: Jacques Bernier

126 Molecular biology of head and neck carcinomas: old challenges, new insights¶

Speaker: Kevin Harrington

15:15 Coffee Break

Proffered papers - Biology IV¶

Conveners: Kevin McMullen, Manjit Dosanjh

127 Vimentin (EMT Marker Protein) Score As One of Predictors Resistance to Erlotinib and Radiotherapy for Patients with Stage III Non-Small Cell Lung Cancer on A Prospective Phase II Trial¶

Speaker: Ritsuko Komaki

Slides 01_RitsukoKomaki.pdf

128 Towards simpler and better prediction of relative biological effect (RBE)¶

Speaker: Bleddyn Jones

129 Combined Radiochemotherapeutical Strategies for Microtubule Stabilizing Agent (MSA)-Resistant Tumors¶

Speaker: Angela Broggini-Tenzer

130 Preclinical Assessment of Efficacy of Radiation Dose Redistribution Based on Intratumoral FDG-PET Uptake¶

Speaker: Ludwig Dubois

Slides 04_LudwigDubois.pdf

131 Fat percentage and hand grip strength in lung cancer: the influence on survival and toxicity¶

Speaker: Kim Smits

Slides 05_KimSmits.pdf

Proffered papers - Physics V (Detectors)¶

Conveners: Paul Lecoq, Ulli Köster

132 Verification of dynamictrajectory radiotherapy based on Monte Carlo¶

Speaker: Michael Fix

133 Development of a transparent photon detector for the online monitoring of IMRT beams¶

Speaker: Rachel Delorme

Slides 02_RachelDelorme.pdf

134 An Intensity Modulated Radiotherapy Beam Monitoring System using a Monolithic Active Pixel Sensor¶

Speaker: Johannes Velthuis

135 Geant4 simulation of a dedicated beam line at the CNAO facility for the study of uveal melanomas¶

Speaker: Edoardo Farina

Slides 04_EdoardoFarina.pdf

136 EndoTOFPET-US: A multimodal ultrasound and time of flight PET endoscope for developing new biomarkers for the prostate and pancreatic cancers¶

Speaker: Etiennette Auffray

Proffered papers - Radiotherapy II¶

Convener: David Brizel

137 The REQUITE project: validating predictive models and biomarkers of radiotherapy toxicity to reduce side-effects¶

Speaker: Tiziana Rancati

Slides 01_TizianaRancati.pdf

138 Potentiation of radiation response by a novel EGFR/DNA targeting molecule in a triple negative breast cancer model¶

Speaker: Beatrice Fournier

139 Studying inter- and intrafraction motion mitigation with sequential 4D CTs of lung tumor patients¶

Speaker: Romain Brevet

Slides 03_RomainBrevet.pdf

140 Time resolved portal dosimetry for Volumetric Modulated Arc Therapy (VMAT) in lung cancer patients with atelectasis¶

Speaker: Mark Podesta

141 Spot-scanning Proton Therapy for Pediatric Parameningeal Rhabdomyosarcomas: Clinical Outcome of 39 Patients Treated at PSI¶

Speaker: Carmen Ares

16:45 CERN visit

19:00 Cocktail in Globe

Friday 14 February ¶

Panel discussion - Clinical trials in particle therapy¶

Conveners: Manjit Dosanjh, Vikram Bhadrasain

slides JamesCox.pdf

142 Panel discussion¶

Speakers: Hirohiko Tsujii, James Cox, Jürgen Debus, Roberto Orecchia

Radiosensitivity modulation - new angles of attack¶

Convener: Richard Kolesnick

143 Growth factor and integrin receptor targeting - there is more to it than just inhibition¶

Speaker: Nils Cordes

144 Notch and radiotherapy: does it matter?¶

Speaker: Marc Vooijs

145 Head-and-neck cancers: towards new, intriguing fractionation schedules¶

Speaker: Jean Bourhis

09:45 Coffee Break

Proffered papers - Biology V¶

Conveners: Tim Maughan, Vikram Bhadrasain

146 Radiosensitization of Non–Small Cell Lung Cancers by Targeting Ionizing Radiation-Induced Activation of ADAM17¶

Speaker: Martin Pruschy

147 Do physiological relevant doses of biguanides have any role in cancer treatment?¶

Speaker: Morten Busk

148 Oral mucosal radiation response (mouse) - relevance of ceramide-induced apoptosis?¶

Speaker: Wolfgang Dörr

149 A phase I/II study of proton and hyperthermia in primary unresectable and recurrent adult soft tissue sarcoma¶

Speaker: Niloy Datta

Slides 04_NiloyDatta.pdf

Proffered papers - Biology VI¶

Conveners: Kevin Prise, Norman Coleman

150 Radiobiological Considerations for Retreatment of Central Nervous System Tumours¶

Speaker: Bleddyn Jones

151 Gadolinium based nanoparticles for radiosensitization of head and neck squamous cell carcinoma¶

Speaker: Lucie Sancey

152 Noninvasive Imaging of Radiation-Induced Lung Inflammation with Positron Emission Tomography (PET) in a Murine Model¶

Speakers: Jin Zhang, Ken Kang Hsin Wang

153 The use of ‘planned overshoot’ for reducing dose to healthy tissue and improve treatments robustness for scanned proton beams¶

Speaker: Francesca Albertini

Slides 04_FrancescaAlbertini.pdf

154 Clinical testing of an in-room imaging system for patient setup verification in particle therapy¶

Speaker: Guido Baroni

155 Reduced side effects by proton microchannel radiotherapy – study in a human skin model¶

Speaker: Stefanie Girst

Slides Girst_ICTR-PHE_2014_pub.pdf

156 Entervision Wp4. Biological Dosimetric Phantom. Proof Of Concept Preliminary Results¶

Speaker: Thiago Viana Miranda Lima

157 A knowledge exchange case study: computational radiotherapy at Cambridge¶

Speaker: Michael Simmons

Proffered papers - Physics VI (Hadrons)¶

Conveners: Hirohiko Tsujii, Ugo Amaldi

158 Intra-fraction tumor tracking based on a surrogate-driven 4D CT motion model in particle radiation therapy¶

Speaker: Guido Baroni

159 Prompt Gamma Imaging at MGH with LaBr3 Scintillating Crystals¶

Speaker: Joao Seco

160 Nanoparticles and protontherapy: disentangling possible physical effects¶

Speaker: Yolanda Prezado

161 95 MeV/A carbon fragmentation studies for hadrontherapy: measurements and comparisons with GEANT4 simulations¶

Speaker: Marc Labalme

162 Properties of therapeutic He, Li and O beams studied with Geant4¶

Speaker: Lucas Burigo

163 Automatic beam dose profiler for scanned pencil beams (protons and carbon ions) at the CNAO hadrontherapy facility¶

Speaker: Aurora Tamborini

164 Proton Interaction Vertex Imaging for carbon therapy quality control¶

Speaker: Regina Rescigno

165 Dual energy CT to reduce range uncertainties in hadrontherapy¶

Speaker: Guillaume Landry

166 Research and development of a TOF-based multi-slit collimated camera for online hadrontherapy monitoring¶

Speaker: Marco Pinto

11:45 Lunch

Symposium - Hadrons¶

Convener: Roberto Orecchia

167 Evolution of technology to optimize the delivery of proton therapy: the third generation¶

Speaker: Thomas Bortfeld

168 Robust optimization of IMPT dose distributions¶

Speaker: Radhe Mohan

Slides 02_RadheMohan.pdf

169 Proton clinical correlates of patient throughput and cyclotron availability¶

Speaker: Kevin McMullen

Slides 03_KevinMcMullen.pdf

Symposium - Imaging¶

Convener: Philippe Lambin

170 Hypoxia Imaging¶

Speaker: Marianne Nordsmark

171 Functional image-based target definition¶

Speaker: Robert Jeraj

Slides 02_RobertJeraj.pdf

172 Predictive and prognostic role of functional imaging of head and neck squamous cell carcinomas¶

Speaker: David Brizel

Symposium - Tumor vascularization¶

Convener: Jens Overgaard

173 Hypoxia modification in experimental tumours¶

Speaker: Daniel Zips

174 The vascular supply and microenvironment of tumours and their significance for cancer therapy¶

Speaker: Michael Horsman

175 Targeting hypoxia through autophagy¶

Speaker: Kasper Rouschop

Symposium - Biomarker driven individualization of radiotherapy - from preclinical validation to clinical trials?¶

Convener: Michael Baumann

176 Biomarker for stratification in radiotherapy - preclinical and early clinical models¶

Speaker: Mechthild Krause

177 Imaging for prescription function¶

Speaker: Daniela Thorwarth

178 How will we develop the evidence base for biologically individualized radiotherapy?¶

Speaker: Tim Maughan

Symposium - Modulation of tumor and normal tissue response to radiation¶

Convener: Simon Powell

179 Carbonic Anhydrase IX inhibitors: a new class of targeted agents¶

Speaker: Philippe Lambin

Slides 01_PhilippeLambin.pdf

180 Immunosensitization by radiotherapy: the example of immunocytokines¶

Speaker: Ludwig Dubois

181 Novel strategies to spare normal tissues from radiation damage¶

Speaker: Marie-Catherine Vozenin

182 Intestinal Stem Cells are Radiation Resistant¶

Speaker: Richard Kolesnick

183 Concluding remarks¶

Speakers: Jacques Bernier, Manjit Dosanjh (CERN)