PET (Positron Emission Tomography) is an advanced imaging technique that uses radiotracers to target a specific biological or pathological process. This process produces radiotracers because the active/targeting compound labeled with the radioisotope is present at trace levels. These radiotracers are used to study biochemical processes in humans and animals. Performing PET on certain oncologic cases such as paediatric applications pose certain unique challenges. Children have an increased risk of harm when exposed to radiation, hence the study of low activity sources was proposed to identify the most effective geometry of the PET scanner for paediatric applications.
This study aims to investigate a set of scintillation crystals including BGO, LSO, LYSO and GAG, and explore their ability to detect the most amount of counts at low activity in order to construct an image with a good resolution and compare the results with high activity for validation purposes. Extensive simulation has been conducted and results will be shown and discussed. This study is significant for paediatric oncologic patients who repeatedly go for check-up sessions.