ICTR-PHE 2016

15 Feb 2016, 12:00 → 19 Feb 2016, 15:40 Europe/Zurich

Centre International de Conferences de Geneve (CICG)

Jacques BERNIER, Manjit Dosanjh

A conference that brings together the International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe.




Journalists can check the accreditation procedure

Please check the ICTR-PHE 2016 main website for more information on the conference itself (venue, committees, sponsorship)

Monday 15 February

13:00 → 13:30 Welcome address and opening

Speakers: Eckhard Elsen (CERN), Jacques Bernier (GSMN), Manjit Dosanjh (CERN)

13:30 → 16:45 Radiobiology

Conveners: Kevin Prise, Marco Durante

13:30 A comprehensive omics approach for development of prognostic or predictive biomarkers in squamous cell carcinoma of the head and neck treated with radiation

Speaker: Michael Story

14:00 What are the Dominant Radiobiological Mechanisms at Play in Stereotactic Radiotherapy?

Speaker: David Brenner

2_David Brenner.pdf

14:30 The symbiosis of science of radiation biology with immunology: Impact on basic and translational research

Speaker: Ahmed Mansoor

3_Ahmed Mansoor.pdf

14:45 The relevance of DNA damage clustering on the nanometer and micrometer scale for the quantitative prediction of radiation effects

Speaker: Michael Scholz

4_Michael Scholz.pdf

15:00 Correlation of Particle Traversals with Clonogenic Survival Using Cell-Fluorescent Ion Track Hybrid Detector

Speaker: Ivana Dokic

5_Ivana Dokic.pdf

15:15 Radiation induced DNA damage in human uveal melanoma cells

Speaker: Katarzyna Jasińska

6_Katarzyna Jasińska.pdf

15:30 Coffee break

16:00 Quantum dots imaging tests on SPAD for nanodosimetric applications

Speaker: Alberto Quaranta

1_Alberto Quaranta.pdf

16:15 Disruption of telomere equilibrium sensitises human cancer cells to DNA repair inhibition and radiation

Speaker: Prakash Hande

ICTR_PHE_Hande_2016_Publication.pdf

16:30 Investigating the impact of a variable RBE on proton dose fractionation across an actively scanned spread-out Bragg peak

Speaker: Kevin Prise

3_Kevin Prise.pdf

16:45 → 18:00 Nuclear Medicine

Conveners: Osman Ratib, Thomas Beyer

16:45 Molecular imaging for theranostics

Speaker: Wim Oyen

17:15 Early variation of FDG-PET radiomics features in NSCLC is related to overall survival - the “delta radiomics” concept

Speaker: Ralph Leijenaar

2_Ralph Leijenaar.pdf

17:30 How to produce scandium-44 and scandium-43 efficiently?

Speakers: Charlotte Duchemin, Jerzy Jastrzębski, Katharina Domnanich

3_Charlotte Duchemin.pdf

5_Jerzy Jastrzebski.pdf

Tuesday 16 February

08:30 → 10:00 Nuclear Medicine

Conveners: Osman Ratib, Thomas Beyer

08:30 Quantitative Theranostics in Nuclear Medicine

Speaker: Michael Lassmann

Geneva_2016_mla_2_short.pdf

09:00 Manufacturing and Nuclear Medicine Applications of the Novel Isotope Sn-117m

Speaker: Nigel Stevenson

2_Nigel Stevenson.pdf

09:15 Contribution of direct and bystander effects to therapeutic efficacy of alpha-RIT using ²¹²Pb-labeled mAbs

Speaker: Jean-Pierre Pouget

09:30 64Cu-Labeled Folate Radioconjugate for PET Imaging of Folate Receptor-Positive Tumors

Speaker: Renata Farkas

09:45 Radiolabeled Acridine Orange (AO) Derivatives as DNA-Targeted Probes for Auger Therapy

Speaker: Antonio Paulo

5_Antonio Paulo.pdf

10:00 → 10:30 Coffee break

10:30 → 14:15 Detectors & Imaging

Conveners: Alberto Del Guerra, Denis Dauvergne

10:30 Imaging for online control of particle therapy

Speaker: Thomas Bortfeld

1_Thomas Bortfeld.pdf

11:00 First clinical application of a prompt gamma based in vivo proton range verification using a knife-edge slit camera

Speaker: Christian Richter

ICTR2016_Richter.pdf

11:30 New Results with Monolithic Scintillators for Time-of-Flight PET

Speaker: Dennis Schaart

11:45 Development of a High Resolution Module for PET scanners

Speaker: Gianluca Stringhini

4_Gianluca Stringhini.pdf

12:00 J-PET: a novel TOF-PET scanner based on plastic scintillators

Speaker: Pawel Moskal

2016_Moskal_ICTRPHE2016.pdf

12:15 Development of a radioguided surgery technique with beta- decays in brain tumor resection

Speaker: Riccardo Faccini

6_Riccardo Faccini.pdf

12:30 Lunch

13:30 Range Verification with Ionoacoustics: simulations and measurements at a clinical proton synchro-cyclotron

Speaker: Sebastian Lehrack

Sebastian Lehrack.pdf

13:45 Measurement of Acoustic Emissions Generated by a Pulsed Proton Beam from a Hospital-Based Clinical Cyclotron

Speaker: Kevin Jones

KevinJones02162016_v2.pdf

14:00 Fast Beam Profile Monitors for Microbeam Radiation Therapy

Speaker: Bjarne Stugu

14:15 → 15:45 New Technologies

Conveners: Hans-Peter Meinzer, Wolfgang Enghardt

14:15 MRI for external beam radiotherapy guidance

Speaker: Jan Lagendijk

14:45 MRI Guided Proton Therapy: pencil beam scanning in an MRI fringe field

Speaker: Brad Oborn

pbs_in_mrpt.pdf

15:00 Nanoparticle Enhanced MRI-Guided Radiation Therapy: Final proof of concept before phase I trial

Speaker: Shady Kotb

3_Shady Kotb.pdf

15:15 Hadron minibeam radiation therapy: feasibility study at the Heidelberg IonBeam Therapy Center (HIT)

Speaker: Immaculada Martínez-Rovira

Immaculada Martínez-Rovira.pdf

15:30 Evaluation of long-term effects of synchrotron-generated microbeams on rat hippocampal neurogenesis

Speaker: Alberto Bravin

15:45 → 16:15 Coffee Break

16:15 → 17:30 New Technologies

Conveners: Hans-Peter Meinzer, Wolfgang Enghardt

16:15 Big Data in Radiation Oncology: data gathering, data processing, algorithms and clinical impact

Speaker: Klaus Maier-Hein

ICTR-PHE2016-pub.pdf

16:45 Expert knowledge and data-driven Bayesian Networks to predict post-RT dyspnea and 2-year survival

Speaker: Timo Deist

2_Timo Deist.pdf

17:00 Dosimetry of ultra high dose rate irradiation for studies on the biological effect induced in normal brain and GBM

Speaker: Kristoffer Petersson

Dosimetry of ultra high dose rate irradiation.pdf

Dosimetry of ultra high dose rate irradiation.pptx

17:15 Geant4 coupled with Comsol heat transfer simulations to determine correction factors of a novel micro-calorimeter

Speaker: Kamran Fathi

4_Kamran Fathi.pdf

18:30 → 19:30 Public talk - Sound for Health - Domenico Vicinanza

Speaker: Domenico Vicinanza

Wednesday 17 February

08:30 → 09:00 ESTRO lecture

Convener: Yolande Lievens

08:30 How emerging trends in basic research & technology will shape clinical research?

Speaker: Eric Deutsch

1_Eric Deutsch.pdf

09:00 → 10:00 Plenary

Conveners: Norman Coleman, Ugo Amaldi

09:00 Is Distributed learning the solution for Rapid Learning Health Care?

Speaker: Philippe Lambin

BigData ICTR Lambin Feb16-ppt.pdf

09:30 Biological stratification in times of highly conformal radiotherapy - status and perspectives

Speaker: Michael Baumann

10:00 → 11:00 Coffee and poster viewing

11:00 → 12:00 Plenary

Conveners: Norman Coleman, Ugo Amaldi

11:00 Biological issues and their clinical implications in proton therapy

Speaker: Radhe Mohan

1_Radhe Mohan.pdf

11:30 Single particle detection for spectroscopic CT and tracking in hadron therapy using Medipix chips

Speaker: Michael Campbell

2_Michael Campbell.pdf

12:00 → 13:00 Lunch & Exhibitor presentations

13:00 → 14:15 Novel approaches in imaging

Convener: Philippe Lambin

13:00 New hypoxia probe development based on mass spectrometry

Speaker: Brad Wouters

13:25 The role of functional imaging for radiation oncology – The whole translational chain from animals to clinics

Speaker: Esther Troost

13:50 Is dual energy CT the next standard imaging modality for radiotherapy?

Speaker: Wouter van Elmpt

vanElmpt ICTR forDistribution.pdf

13:00 → 14:15 Particle therapy (I)

Session sponsored by Enlight

Conveners: Hirohiko Tsujii, Jürgen Debus

13:00 Proton Radiation Therapy: Current Status at Massachusetts General Hospital

Speaker: Thomas DeLaney

1_Thomas DeLaney.pdf

13:25 MedAustron - status and vision

Speaker: Eugen Hug

2_Eugen Hug.pdf

13:50 Particle therapy centre in Shanghai

Speaker: Zhen Zhang

Geneva 2016-Zhen Zhang modified.pdf

13:00 → 14:15 Proffered papers- clinical

Convener: Carlo Greco

13:00 Urethra-sparing SBRT for prostate cancer: dosimetric optimization with VMAT vs. IMRT and the learning curve effect

Speaker: Thomas Zilli

1_Thomas Zilli.pdf

13:15 A novel method to predict a priori the toxicity reduction of a prostate-rectum spacer: Virtual Rectum Spacer

Speaker: Ben Vanneste

2_Ben Vanneste.pdf

13:30 Local Tumor Flare Following Radiosurgery and Ipilimumab (Ipi) for Melanoma Brain Metastases: Increased Immune Response?

Speaker: Caroline Chung

3_Caroline Chung.pdf

13:45 Response-based Bayesian Network Approaches for Adaptive Radiotherapy of Non-Small Cell Lung Cancer (NSCLC)

Speaker: Randall Ten Haken

4_Randall Ten Haken.pdf

14:00 Further Development of Spinal Tissue Radiotherapy Re-treatment Modelling, with inclusion of Hadrontherapy

Speaker: Bleddyn Jones

5_Bleddyn Jones.pdf

14:15 → 15:45 Oral poster presentation- Physics/Biology

Convener: Dag-Rune Olsen

14:15 Proton Minibeam Radiation Therapy (pMBRT): implementation at a clinical center

Speaker: Cécile Peucelle

1_Cécile Peucelle_Proton Minibeam Radiation Therapy (pMBRT)- implementation at a clinical center.pdf

14:25 Investigation of the use of inhomogeneous fractional dose distributions in IMPT to improve the therapeutic index

Speaker: Lorenzo Manganaro

2_Lorenzo Manganaro.pdf

14:35 Accuracy of portal dosimetry in hybrid IMRT and VMAT treatment of the prostate

Speaker: James Bedford

3_James Bedford_Accuracy of portal dosimetry in hybrid IMRT and VMAT treatment of the prostate.pdf

14:45 ODSH as a countermeasure for radiation-induced thrombocytopenia: Dosimetric studies

Speaker: Stephen Avery

4_Stephen Avery.pdf

14:55 Measurements of Reactive Oxygen Species production induced by Gold Nanoparticles in Radiotherapy protoco

Speaker: Piergiorgio Cerello

5_Piergiorgio Cerello.pdf

15:05 NanoxTM: A new multiscale theoretical framework to predict cell survival in the context of particle therapy

Speaker: Micaela Cunha

6_Micaela Cunha.pdf

15:15 Simulation of cell survival for proton broad and minibeam radiotherapy with hexagonal and square minibeam alignment

Speaker: Matthias Sammer

7_Matthias Sammer.pdf

15:25 Microbeam Radiation Therapy (MRT): achievements and future perspectives

Speaker: Elke Bräuer-Krisch

8_Elke Bräuer-Krisch.pdf

15:35 The role of adipose stromal cells for reversal of radiation fibrosis

Speaker: Fei-Fei Liu

9_Fei-Fei Liu.pdf

14:15 → 15:55 Panel discussion: Optimizing treatment planning and delivery

Conveners: Hans Langendijk, Søren Bentzen

14:15 Current and future strategies developed at Paul Scherrer Institute

Speaker: Alessandra Bolsi

1_Alessandra Bolsi.pdf

14:40 Optimizing prostate cancer irradiation: from technology to fractionation

Speaker: Raymond Miralbell

2_Raymond Miralbell.pdf

15:05 Technological advancement in radiation oncology

Speaker: Hak Choy

Geneva.pdf

15:30 Main challenges in adaptive radiotherapy

Speaker: Jan-Jakob Sonke

Sonke ICTR 2016.pdf

14:15 → 15:55 Panel discussion: Therapeutic targets: towards the cutting edge

Convener: Karin Haustermans

14:15 The Biology of Single Dose Radiotherapy

Speaker: Zvi Fuks

1_Zvi Fuks.pdf

14:40 Are there common signaling pathways among highly radioresistant tumors? The examples of high grade gliomas and sarcomas

Speaker: Elizabeth Moyal

2_Elizabeth Moyal.pdf

15:05 HIF-related therapeutic windows

Speaker: Amato Giaccia

3_Amato Giaccia.pdf

15:30 Vascular disrupting agents: a new avenue of research

Speaker: Michael Horsman

4_Michael Horsman.pdf

15:55 → 16:30 Coffee break

16:30 → 17:45 Novel strategies to overcome cancer (I): Immunology-based attacks

Convener: Marce Verheij

16:30 Oncolytic viruses

Speaker: Kevin Harrington

1_Kevin Harrington.pdf

16:55 Synergy of radiotherapy and cancer vaccines in HPV-positive tumors

Speaker: Eric Deutsch

2_Eric Deutsch.pdf

17:20 Radiotherapy and the immunocytokine L19-IL2: a perfect match for an abscopal effect with long-lasting memory

Speaker: Ludwig Dubois

3_Ludwig Dubois.pdf

16:30 → 17:45 Novel strategies to overcome cancer (II): Enhancing the ratio between tumor cell killing and normal tissue protection

Convener: Raymond Miralbell

16:30 Pelvic tumor irradiation: new tools to reduce toxicity: from technology to drugs

Speaker: Karin Haustermans

1_Karin Haustermans.pdf

16:55 Towards a new type of irradiation

Speaker: Jean Bourhis

Toward new types of irradiation.pdf

17:20 Treatment outcome in patients treated with single-dose irradiation (SDRT) for oligometastatic disease

Speaker: Carlo Greco

3_Carlo Greco.pdf

16:30 → 17:45 Proffered papers - Emerging technologies

Conveners: Marco Silari, Vincenzo Patera

16:30 Geometrical interpretation of TOF PET raw data in commercial PET-CT scanner for SNR optimization

Speaker: Chiara Gianoli

1_Chiara Gianoli.pdf

16:45 Characterization and test beam results of a LaBr3 Compton Telescope for treatment monitoring

Speaker: Gabriela Llosá

2_Gabriela Llosá.pdf

17:00 Small Large Momentum Acceptance Gantries for Proton and Carbon Cancer Therapy

Speaker: Dejan Trbojevic

3_Dejan Trbojevic.pdf

17:15 X-Ray Phase contrast micro-imaging in neuroscience

Speaker: Giacomo Barbone

ICTR-PHE_Barbone_Presentation.pdf

17:30 Water based 3D optical dose imaging for particle therapy

Speaker: Oksana Kavatsyuk

5_Oksana Kavatsyuk.pdf

19:00 → 21:00 Gala dinner with Keynote by Vytenis Andriukaitis, EC Health Commissioner

Thursday 18 February

08:15 → 08:50 GH Fletcher Lecture

Convener: James Cox

08:15 Multimodality Precision Medicine

Speaker: Søren Bentzen

08:50 → 10:05 Genomics

Convener: Simon Powell

08:50 The search for genetic predictors of radiotherapy response

Speaker: Dirk De Ruysscher

1_Dirk De Ruysscher_Genetic predictors of radiation response.pdf

09:15 RSI: A genomic signature of radiosensitivity

Speaker: Peter A. Johnstone

2016 PHE ICTR Geneva releasable.pdf

2016 PHE ICTR Geneva releasable.pdf

09:40 Radiomics in Liquid Biopsies

Speaker: Frederic Zenhausern

08:50 → 10:05 Panel discussion: Clinical Trials for particle therapy

Conveners: Roberto Orecchia, Vikram Bhadrasain

08:50 Trials in USA

Speaker: James Cox

1_James Cox.pdf

09:15 Trials in Germany

Speaker: Jürgen Debus

2_Jürgen Debus.pdf

09:40 Clinical trials for carbon-ion radiotherapy in Japan

Speaker: Hirohiko Tsujii

3_Hirohiko Tsujii.pdf

10:05 → 10:30 Coffee break

10:30 → 12:10 EORTC session

Conveners: Sofia Rivera, Wilfried Budach

10:30 Radiotherapy quality assurance platform of the EORTC

Speaker: Damien Weber

1_Damien Weber.pdf

10:52 Radiotherapy quality assurance platform of the EORTC

Speaker: André Branquinho

2_André Branquinho.pdf

11:02 Synergy of targeted agents and radiotherapy

Speaker: Sofia Rivera

3_Sofia Rivera.pdf

11:24 Lessons from translational research in EORTC Glioma trials

Speaker: Monika Hegi

4_Monika Hegi.pdf

11:46 Data from the EORTC Cancer Survivorship Task Force

Speaker: Conny Vrieling

5_Conny Vrieling.pdf

10:30 → 11:45 Proffered papers - Detectors and Imaging

Conveners: Katia Parodi, Paul Lecoq

10:30 Study of the radiation produced by therapeutic He, C and O ion beams impinging on a PMMA target

Speaker: Alessio Sarti

1_Alessio Sarti.pdf

10:45 Short-lived Positron Emitters in Beam-on PET ImagingDuring Proton Therapy

Speaker: Tom Buitenhuis

2_Tom Buitenhuis.pdf

11:00 DoPET: an in-treatment monitoring system for particle therapy

Speaker: Valeria Rosso

3_Valeria Rosso.pdf

11:15 Commissioning of a Compton camera for ion beam range verification via prompt gamma detection using low-energy and clinical particle beams

Speaker: Saad Aldawood

4_Saad Aldawood.pdf

11:30 Prompt Gamma-ray Timing experiment during different modalities of proton beam delivery

Speaker: Thomas Kormoll

5_Thomas Kormoll.pdf

10:30 → 12:00 Proffered papers - Radiobiology

Conveners: Mechthild Krause, Ulli Köster

10:30 The effect of fractionated administration of thalidomide at γ-ray irradiation on tumor response and lung metastasis

Speaker: Shin-ichiro Masunaga

1_Shin-ichiro Masunaga.pdf

10:45 Predictive Biomarkers for Improving Radiation Therapy

Speaker: Pataje Prasanna

Pataje Prasanna.pdf

11:00 Targeted Radionuclide Therapy with 161Tb: Investigation of Anti-Tumor Effects and Undesired Side Effects

Speaker: Cristina Müller

11:15 The relationship between absorbed dose and DNA Damage in Lymphocytes after radionuclide therapy

Speaker: Uta Eberlein

4_Uta Eberlein.pdf

11:30 Modeling the effect of symmetrical division of cancer stem cells on tumour response to radiation

Speaker: Loredana Marcu

5_Loredana Marcu.pdf

11:45 A dose response analysis of the patients treated with Boron Neutron Capture Therapy (BNCT) in Finland in 1999 to 2011

Speaker: Hanna Koivunoro

6_Hanna Koivunoro.pdf

12:00 → 13:00 Lunch & Start-up presentations

13:00 → 13:30 European School of Oncology - E. van der Schueren Award

Convener: Fedro Peccatori

13:00 Tackling Phenotypic Diversity to Increase Cures

Speaker: Brad Wouters

13:30 → 14:45 Novel strategies to overcome cancer: Tumor cell radiosensitivity modulation

Conveners: Jacques Bernier, Jean Bourhis

13:30 Novel anti-tumor agents targeting cell membrane

Speaker: Marcel Verheij

Verheij ICTR2016final.pdf

13:55 Stroma mediated wound healing signals and cell response to radiation

Speaker: Marie-Catherine Vozenin

14:20 Targeting tumor heterogeneity

Speaker: Gerben Borst

13:30 → 14:45 Proffered papers - Physics

Convener: Thomas Bortfeld

13:30 Towards analytic dose calculation for MR guided particle beam therapy

Speaker: Hermann Fuchs

1_Hermann Fuchs.pdf

13:45 Experimental dosimetric comparisons of protons, helium, carbon and oxygen ion beams

Speaker: Thomas Tessonnier

2_Thomas Tessonnier.pdf

14:00 Implementation of an analytical solution to lateral dose prediction in a proton therapy treatment planning system

Speaker: Valentina Elettra Bellinzona

3_Valentina Elettra Bellinzona.pdf

14:15 Utilizing CBCT data for dose calculation in adaptive IMPT

Speaker: Christopher Kurz

4_Christopher Kurz.pdf

14:30 Can we replace high quality simulation CT by simple kV-cone-beam CT images to extract an externally validated radiomics signature?

Speaker: Janita van Timmeren

5_Janita van Timmeren.pdf

13:30 → 14:45 Revisiting RBE

Convener: Jens Overgaard

13:30 In-vitro RBE

Speaker: Marco Durante

1_Marco Durante.pdf

13:55 Carbon ion radiotherapy: do we understand each other? How to compare differentt RBE-weighted dose systems in the clinical setting

Speaker: Piero Fossati

2_Piero Fossati.pdf

14:20 Physics and RBE

Speaker: Tony Lomax

3_Tony Lomax.pdf

14:45 → 16:15 Coffee and poster viewing

Coffee break sponsored by RaySearch

16:15 → 17:30 Emerging challenges in combating cancer

Convener: Vincent Grégoire

16:15 Emerging challenges in combating cancer

Speaker: Norman Coleman

1_Norman Coleman.pdf

16:40 Targeted Treatment for the Non- Small Cell Lung Cancer

Speaker: Ritsuko Komaki

2_Ritsuko Komaki.pdf

17:05 Magnetic resonance temperature imaging in clinical hyperthermia: past experience and prospects

Speaker: Peter Wust

16:15 → 17:30 Particle therapy (II)

Conveners: Damien Weber, Jacques Balosso

16:15 Current status of particle therapy at CNAO

Speaker: Roberto Orecchia

1_Roberto Orecchia.pdf

16:40 Integration of economic data in clinical trials

Speaker: Yolande Lievens

2_Yolande Lievens.pdf

17:05 Current status of particle therapy in The Netherlands

Speaker: Hans Langendijk

3_Hans Langendijk.pdf

16:15 → 17:30 Proffered papers -Biology

Conveners: Amato Giaccia, Michael Horsman

16:15 Radiation treatment monitoring using multifunctional imaging in prostate tumour xenografts

Speaker: Natalia Arteaga-Marrero

1_Natalia Arteaga-Marrero.pdf

16:30 Robustness and reliability of PET-based identification and quantification of tumor hypoxia, using simple static or more complex scan acquisitions

Speaker: Morten Busk

ICTR_2016_MB.pdf

16:45 Variable RBE in proton therapy: comparison of model predictions and their impact on clinical-like cranial lesions

Speaker: Julia Bauer

3_Julia Bauer.pdf

17:00 Inhibiting the actions of cathepsin L effects both tumour initiation and metastasis formation

Speaker: Thomas Wittenborn

4_Thomas Wittenborn.pdf

17:15 Plerixafor Improves Local Control and Reduces Metastases in Cervical Cancer Treated with Radiotherapy and Chemotherapy

Speaker: Michael Milosevic

5_Michael Milosevic.pdf

Friday 19 February

08:30 → 09:45 Biomolecular mechanisms driving modulation of tumor cell sensitivity

Conveners: Martin Pruschy, Zvi Fuks

08:30 Genetic and pharmacological inhibition of autophagy after irradiation

Speaker: Kasper Rouschop

1_Kasper Rouschop.pdf

08:55 Oncometabolite lactate promotes tumour growth

Speaker: Pierre Sonveaux

09:20 Determining cell radiosensitivity using assays in ex vivo irradiated tumour specimens

Speaker: Daniel Zips

3_Daniel Zips.pdf

08:30 → 09:45 MEDICIS - PROMED program

Conveners: Osman Ratib, Thierry Stora

08:30 MEDICIS-PROMED : a ITN Marie-Curie network on nuclear medicine and 11C-based hadron-therapy

Speaker: Johanna Pitters

1_Johanna Pitters.pdf

08:40 MEDICIS-PROMED: MEDICIS-Produced Radioisotope Beams for Medicine an Innovative Training Network

Speaker: John Prior

09:05 Recurrent glioblastoma multiforme – targeted alpha therapy with 213Bi-DOTA-Substance P

Speaker: Frank Bruchertseifer

3_Frank Bruchertseifer.pdf

09:25 Medical isotope production at TRIUMF and future collaboration with MEDICIS-PROMED

Speaker: Yann Seimbille

4_Yann Seimbille.pdf

08:30 → 09:40 Oral poster presentation- Detectors and Imaging

Conveners: Michael Campbell, Mike Waligórski

08:30 Comparison of Arterial Input Functions by Magnitude and Phase Signal Measurement in DCE MRI of brain cancer patients

Speaker: Catherine Coolens

1_Catherine Coolens.pdf

08:40 Fast calibration of the range of Carbon ionswith in-beam PET of Boron-8 nuclei

Speaker: Caterina Cuccagna

2_Caterina Cuccagna.pdf

08:50 An online beam monitor detector for medical applications of ion beams

Speaker: Saverio Braccini

3_Saverio Braccini.pdf

09:00 The GEMPIX detector for energy deposition measurements in Hadrontherapy

Speaker: Fabrizio Murtas

4_Fabrizio Murtas.pdf

09:10 GPU based iterative CBCT for prospective motion compensated algorithm for radiation therapy

Speaker: Ander Biguri

5_Ander Biguri.pdf

09:20 Measurements and simulations of in-phantom neutron dose from a proton pencil beam

Speaker: Kristian Ytre-Hauge

6_Kristian Ytre-Hauge.pdf

09:30 CHIC – A Multi-scale Modelling Platform for in-silico Oncology

Speaker: Daniel Abler

7_Daniel Abler.pdf

09:45 → 10:15 Coffee break

10:15 → 11:25 Oral poster presentation - Miscellaneous

Conveners: Alessandra Bolsi, Jan Alsner

10:15 Clinical validation of the M5L lung Computer-Assisted Detection system

Speaker: Piergiorgio Cerello

1_Piergiorgio Cerello.pdf

10:25 Tuning of a 4D ML reconstruction strategy for treatment verification in ion beam radiotherapy

Speaker: Katia Parodi

2_Katia Parodi given by Chiara Giannoli.pdf

10:35 Differential cross sections measurements for hadrontherapy: 50 MeV/n 12C reactions on H, C, Al, O and natTi targets

Speaker: Clovis Divay

3_Divay Clovis.pdf

10:45 Metal implanted multi-functional nanovectors for targeted radiotherapy and diagnostics of cancer

Speaker: Asénath Etilé

4_Asénath Etilé.pdf

10:55 The Malthus Project - updated predictions of national radiotherapy demand to 2030

Speaker: Thomas Mee

Talk-MKF-HO.pdf

11:05 The use of radiobiological TCP and NTCP models to validate the dose calculation algorithm and readjust the prescribed dose

Speaker: Jacques Balosso

6_Jacques Balosso.pdf

11:15 Status of the CaLIPSO High-Resolution PET Project

Speaker: Xavier Mancardi

7_Xavier Mancardi.pdf

10:15 → 11:25 Oral poster presentation- Clinics

Convener: Esther Troost

10:15 The use of 149Tb and 152Tb in preclinical investigations: an update on its mass separation and subsequent application for imaging and therapy

Speaker: Nicholas van der Meulen

10:25 Design of electronic data processing system for radiotherapy study: lessons learned from VoxTox

Speaker: Marina Romanchikova

2_Marina Romanchikova.pdf

10:35 Assessment tool to quantify and visualize treatment plan robustness regarding patient setup

Speaker: Michael Fix

Talk-MKF-HO.pdf

10:45 A Hypercellular Component of Glioblastoma Identified by High b-value Diffusion Weighted Imaging

Speaker: Yue Cao

4_Yue Cao.pdf

10:55 Treatment of moving targets with active scanning carbon ion beams

Speaker: Piero Fossati

5_Piero Fossati.pdf

11:05 Distributed learning: predictive models based on data from multiple hospitals without data leaving the hospital

Speaker: Arthur Jochems

6_Arthur Jochems.pdf

11:15 A clinical protocol for Simultaneous Integrated Boost for proton treatment of Head and Neck carcinoma

Speaker: Francesca Belosi

7_Francesca Belosi.pdf

10:15 → 11:30 Panel discussion: OPENMED

Conveners: Jens Overgaard, Manjit Dosanjh

10:15 Conceptual Design report for OpenMED

Speaker: Ghislain Roy

1_Ghislain Roy.pdf

10:40 OPENMED: Topics, Issues and Wishes

Speaker: Mike Waligórski

2_Mike Waligórski.pdf

11:05 Role of the CERN International Strategy Committee in the LEIR initiative: Biology

Speaker: Philippe Lambin

3_Philippe Lambin.pdf

11:30 → 12:00 Poster viewing

12:00 → 12:45 Lunch

12:45 → 14:00 Panel discussion: Panel discussionTargeting Strategies

Convener: Daniel Zips

12:45 Multimodal approach to assess tumour vasculature and potential treatment effect

Speaker: Dag Rune Olsen

1_Dag Rune Olsen.pdf

13:10 Hypoxia-guided adaptive radiation dose escalation in head and neck carcinoma

Speaker: Vincent Gregoire

2_Vincent Gregoire.pdf

13:35 Microtubule-stabilizing agents with inhibitors of angiogenesis to overcome resistance

Speaker: Martin Pruschy

Pruschy 2016 PHE ICTR Geneva releasable.pdf

12:45 → 14:00 Preclinical models

Convener: Richard Kolesnick

12:45 Orthotopic tumor models for glioma and NSCLC

Speaker: Jan Theys

1_Jan Theys.pdf

13:10 High Performance Preclinical Irradiation Through Optimized Dual Focal Spot Dose Painting and Online Virtual Isocenter Radiation Field Targeting

Speaker: David Jaffray

2_David Jaffray.pdf

13:35 Studying radiotherapy resistance of BRCA1-mutated mammary tumors

Speaker: Sven Rottenberg

3_Sven Rottenberg.pdf

12:45 → 14:00 Winning posters

Conveners: Jacques Bernier, Manjit Dosanjh

Olga Sokol.pdf

14:00 → 15:15 Modulating response to radiation

Convener: Elizabeth Moyal

14:00 Balanced checkpoint activation: genomic stability and cell response to radiation

Speaker: Simon Powell

1_Simon Powell.pdf

14:25 Macrophage reprogramming for anticancer therapy

Speaker: Michele De Palma

14:50 Focal adhesion signaling and therapy resistance in cancer

Speaker: Anne Vehlow

14:00 → 15:15 Research seminar:Overcoming cancer radioresistance

Convener: Brad Wouters

14:00 Factors of radioresistance in prostate cancer

Speaker: Mechthild Krause

14:25 Targeting NOTCH pathway in Glioblastoma

Speaker: Marc Vooijs

2_Jan Theys_Marc Vooijs.pdf

14:50 Human Sphingolipid Biomarkers of Single Dose Radiotherapy: A Clinical trial

Speaker: Richard Kolesnick

15:15 → 15:40 Concluding remarks

Conveners: Jacques Bernier, Manjit Dosanjh